Synchronous multifocal necrotizing fasciitis prognostic factors: a retrospective case series study in a single center

Ching Yu Lee, Yen Yao Li, Tsan Wen Huang, Tsung Yu Huang, Wei Hsiu Hsu, Yao Hung Tsai, Jou Chen Huang, Kuo Chin Huang

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Purpose: No reports have been published on synchronous multifocal necrotizing fasciitis (SMNF), a multifocal presence of necrotizing fasciitis in different extremities. We evaluated the clinical characteristics and outcomes of SMNF. Methods: Eighteen patients (14 men, 4 women; mean age: 59 years) diagnosed with SMNF of the extremities between January 2004 to December 2012 were enrolled and evaluated. Results: Vibrio species were the most commonly (78%; n = 14) isolated; others were two cases (11%) of Aeromonas spp., one case (6%) of group A β-hemolytic streptococcus, and one case of coagulase-negative staphylococcus. SMNF was in the bilateral lower limbs (72%; n = 13), bilateral upper limbs (17%; n = 3), and one patient with one upper and one lower limb (11%). Non-surviving patients had more bilateral lower limb involvement and thrombocytopenia. Conclusions: Most patients with SMNF were male and had bilateral lower limb and marine Gram-negative bacteria involvement. The mortality of SMNF remained extremely high in patients with involvement of bilateral lower limb and initial thrombocytopenia.

Original languageEnglish
Pages (from-to)757-763
Number of pages7
JournalInfection
Volume44
Issue number6
DOIs
Publication statusPublished - Dec 1 2016

Keywords

  • Multifocal
  • Necrotizing fasciitis
  • Prognostic factors
  • Synchronous

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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