Symptoms concern and quality of life in hepatobiliary cancers

Virginia Sun, Betty Ferrell, Gloria Juarez, Lawrence D. Wagman, Yun Yen, Vincent Chung

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Purpose/Objectives: To describe the symptoms concern of patients with hepatocellular carcinoma (HCC) and pancreatic cancer and explore the affect of symptoms on patients' quality of life (QOL). Design: Descriptive, longitudinal study. Setting: Ambulatory clinics of a comprehensive cancer center. Sample: 45 patients actively receiving treatment for either HCC or pancreatic cancer. Methods: Patients were followed from baseline for three months, with outcome measures repeated monthly. Outcome measures included the Functional Assessment of Cancer Therapy - Hepatobiliary (FACT-Hep) and the Functional Assessment of Chronic Illness Therapy - Spirituality Subscale (FACIT-Sp-12). Descriptive analysis of demographic, treatment, and symptom data was conducted, followed by two-way repeated measures analysis of variance of FACT-Hep and FACIT-Sp-12 scale scores by diagnosis and type of treatment. Main Research Variables: Symptoms, QOL. Findings: Overall QOL is poor in patients with hepatobiliary cancer, and this trend continues over time. Symptoms such as abdominal pain, fatigue, weight loss, and poor appetite commonly are reported in this population. Conclusions: Patients with hepatobiliary cancer suffer from multiple symptoms that may have a negative affect on overall QOL. Specific QOL domains, such as physical and functional well-being, are of particular concern for patients. Implications for Nursing: The identification of specific symptom and QOL concerns in hepatobiliary cancers will enhance clinical care and aid in the future development of multidisciplinary interventions for this understudied cancer population.

Original languageEnglish
Pages (from-to)357
Number of pages1
JournalOncology Nursing Forum
Volume35
Issue number3
DOIs
Publication statusPublished - May 2008
Externally publishedYes

Fingerprint

Quality of Life
Neoplasms
Liver Neoplasms
Pancreatic Neoplasms
Hepatocellular Carcinoma
Therapeutics
Outcome Assessment (Health Care)
Spirituality
Appetite
Abdominal Pain
Population
Fatigue
Longitudinal Studies
Weight Loss
Analysis of Variance
Nursing
Chronic Disease
Demography
Research

ASJC Scopus subject areas

  • Oncology(nursing)

Cite this

Symptoms concern and quality of life in hepatobiliary cancers. / Sun, Virginia; Ferrell, Betty; Juarez, Gloria; Wagman, Lawrence D.; Yen, Yun; Chung, Vincent.

In: Oncology Nursing Forum, Vol. 35, No. 3, 05.2008, p. 357.

Research output: Contribution to journalArticle

Sun, V, Ferrell, B, Juarez, G, Wagman, LD, Yen, Y & Chung, V 2008, 'Symptoms concern and quality of life in hepatobiliary cancers', Oncology Nursing Forum, vol. 35, no. 3, pp. 357. https://doi.org/10.1188/08.ONF.E45-E52
Sun, Virginia ; Ferrell, Betty ; Juarez, Gloria ; Wagman, Lawrence D. ; Yen, Yun ; Chung, Vincent. / Symptoms concern and quality of life in hepatobiliary cancers. In: Oncology Nursing Forum. 2008 ; Vol. 35, No. 3. pp. 357.
@article{9b9ef8fc71ee441d86d26faf54d861d0,
title = "Symptoms concern and quality of life in hepatobiliary cancers",
abstract = "Purpose/Objectives: To describe the symptoms concern of patients with hepatocellular carcinoma (HCC) and pancreatic cancer and explore the affect of symptoms on patients' quality of life (QOL). Design: Descriptive, longitudinal study. Setting: Ambulatory clinics of a comprehensive cancer center. Sample: 45 patients actively receiving treatment for either HCC or pancreatic cancer. Methods: Patients were followed from baseline for three months, with outcome measures repeated monthly. Outcome measures included the Functional Assessment of Cancer Therapy - Hepatobiliary (FACT-Hep) and the Functional Assessment of Chronic Illness Therapy - Spirituality Subscale (FACIT-Sp-12). Descriptive analysis of demographic, treatment, and symptom data was conducted, followed by two-way repeated measures analysis of variance of FACT-Hep and FACIT-Sp-12 scale scores by diagnosis and type of treatment. Main Research Variables: Symptoms, QOL. Findings: Overall QOL is poor in patients with hepatobiliary cancer, and this trend continues over time. Symptoms such as abdominal pain, fatigue, weight loss, and poor appetite commonly are reported in this population. Conclusions: Patients with hepatobiliary cancer suffer from multiple symptoms that may have a negative affect on overall QOL. Specific QOL domains, such as physical and functional well-being, are of particular concern for patients. Implications for Nursing: The identification of specific symptom and QOL concerns in hepatobiliary cancers will enhance clinical care and aid in the future development of multidisciplinary interventions for this understudied cancer population.",
author = "Virginia Sun and Betty Ferrell and Gloria Juarez and Wagman, {Lawrence D.} and Yun Yen and Vincent Chung",
year = "2008",
month = "5",
doi = "10.1188/08.ONF.E45-E52",
language = "English",
volume = "35",
pages = "357",
journal = "Oncology Nursing Forum",
issn = "0190-535X",
publisher = "Oncology Nursing Society",
number = "3",

}

TY - JOUR

T1 - Symptoms concern and quality of life in hepatobiliary cancers

AU - Sun, Virginia

AU - Ferrell, Betty

AU - Juarez, Gloria

AU - Wagman, Lawrence D.

AU - Yen, Yun

AU - Chung, Vincent

PY - 2008/5

Y1 - 2008/5

N2 - Purpose/Objectives: To describe the symptoms concern of patients with hepatocellular carcinoma (HCC) and pancreatic cancer and explore the affect of symptoms on patients' quality of life (QOL). Design: Descriptive, longitudinal study. Setting: Ambulatory clinics of a comprehensive cancer center. Sample: 45 patients actively receiving treatment for either HCC or pancreatic cancer. Methods: Patients were followed from baseline for three months, with outcome measures repeated monthly. Outcome measures included the Functional Assessment of Cancer Therapy - Hepatobiliary (FACT-Hep) and the Functional Assessment of Chronic Illness Therapy - Spirituality Subscale (FACIT-Sp-12). Descriptive analysis of demographic, treatment, and symptom data was conducted, followed by two-way repeated measures analysis of variance of FACT-Hep and FACIT-Sp-12 scale scores by diagnosis and type of treatment. Main Research Variables: Symptoms, QOL. Findings: Overall QOL is poor in patients with hepatobiliary cancer, and this trend continues over time. Symptoms such as abdominal pain, fatigue, weight loss, and poor appetite commonly are reported in this population. Conclusions: Patients with hepatobiliary cancer suffer from multiple symptoms that may have a negative affect on overall QOL. Specific QOL domains, such as physical and functional well-being, are of particular concern for patients. Implications for Nursing: The identification of specific symptom and QOL concerns in hepatobiliary cancers will enhance clinical care and aid in the future development of multidisciplinary interventions for this understudied cancer population.

AB - Purpose/Objectives: To describe the symptoms concern of patients with hepatocellular carcinoma (HCC) and pancreatic cancer and explore the affect of symptoms on patients' quality of life (QOL). Design: Descriptive, longitudinal study. Setting: Ambulatory clinics of a comprehensive cancer center. Sample: 45 patients actively receiving treatment for either HCC or pancreatic cancer. Methods: Patients were followed from baseline for three months, with outcome measures repeated monthly. Outcome measures included the Functional Assessment of Cancer Therapy - Hepatobiliary (FACT-Hep) and the Functional Assessment of Chronic Illness Therapy - Spirituality Subscale (FACIT-Sp-12). Descriptive analysis of demographic, treatment, and symptom data was conducted, followed by two-way repeated measures analysis of variance of FACT-Hep and FACIT-Sp-12 scale scores by diagnosis and type of treatment. Main Research Variables: Symptoms, QOL. Findings: Overall QOL is poor in patients with hepatobiliary cancer, and this trend continues over time. Symptoms such as abdominal pain, fatigue, weight loss, and poor appetite commonly are reported in this population. Conclusions: Patients with hepatobiliary cancer suffer from multiple symptoms that may have a negative affect on overall QOL. Specific QOL domains, such as physical and functional well-being, are of particular concern for patients. Implications for Nursing: The identification of specific symptom and QOL concerns in hepatobiliary cancers will enhance clinical care and aid in the future development of multidisciplinary interventions for this understudied cancer population.

UR - http://www.scopus.com/inward/record.url?scp=48249111339&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48249111339&partnerID=8YFLogxK

U2 - 10.1188/08.ONF.E45-E52

DO - 10.1188/08.ONF.E45-E52

M3 - Article

VL - 35

SP - 357

JO - Oncology Nursing Forum

JF - Oncology Nursing Forum

SN - 0190-535X

IS - 3

ER -