Surgical results of squamous cell carcinoma of the esophagus in young patients

Chien H. Tsai, Han Shui Hsu, Liang Shun Wang, Hao W. Wang, Yu Chung Wu, Chih Cheng Hsieh, Biing Shiun Huang, Wen H. Hsu, Min Hsiung Huang

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background. Squamous cell carcinoma of the esophagus (ESCC) is one of the ten most common cancers in Taiwan. Surgical resection is the mainstay of the treatment. Young patients with ESCC are reported to have poor surgical outcome. This retrospective and comparative study is to evaluate the clinicopathologic difference and survival between young and elderly patients. Methods. From January 1985 to December 2000, totally 797 patients with esophageal cancer received esophagectomy with reconstruction at our institution. Among them, 12 patients who received neoadjuvant concurrent chemo-radiotherapy followed by esophagectomy were excluded from this study. The other 785 patients were divided into two groups. Group I included 67 patients aged 50 or younger (8.5%) and group II included 718 patients aged over 50 years (91.5%). The clinical data were collected by chart review and follow-up data were collected through outpatient department record or telephone contact. These two groups were analyzed and compared regarding sex ratio, exposure to tobacco or alcohol, surgical mortality rate and 5-year survival rate. Results. There was no difference in gender distribution between young and old patients groups. More patients in the young patients group had the habits of alcohol and tobacco consumption than in the elder patients group. The surgical (30-day) mortality was 2.98% in the young patient group, and 5.43% in the elder group. The 5-year survival rate was better in young patients group than in elder patients group but there was no statistical significance. Survival in young patients group was significantly related to TNM staging system. Conclusions. More young patients with ESCC had the habit of smoking and drinking. There was no statistical difference between the groups in clinical variables, surgical mortality and survival. The survival rate was significantly related to the TNM tumor stage.

Original languageEnglish
Pages (from-to)288-293
Number of pages6
JournalJournal of the Chinese Medical Association
Volume66
Issue number5
Publication statusPublished - May 1 2003
Externally publishedYes

Fingerprint

Esophagus
Squamous Cell Carcinoma
Esophagectomy
Survival Rate
Habits
Survival
Mortality
Neoplasm Staging
Sex Ratio
Tobacco Use
Esophageal Neoplasms
Taiwan
Telephone
Alcohol Drinking
Drinking
Tobacco
Neoplasms
Outpatients
Radiotherapy
Retrospective Studies

Keywords

  • Esophagus
  • Squamous cell carcinoma
  • Young

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Tsai, C. H., Hsu, H. S., Wang, L. S., Wang, H. W., Wu, Y. C., Hsieh, C. C., ... Huang, M. H. (2003). Surgical results of squamous cell carcinoma of the esophagus in young patients. Journal of the Chinese Medical Association, 66(5), 288-293.

Surgical results of squamous cell carcinoma of the esophagus in young patients. / Tsai, Chien H.; Hsu, Han Shui; Wang, Liang Shun; Wang, Hao W.; Wu, Yu Chung; Hsieh, Chih Cheng; Huang, Biing Shiun; Hsu, Wen H.; Huang, Min Hsiung.

In: Journal of the Chinese Medical Association, Vol. 66, No. 5, 01.05.2003, p. 288-293.

Research output: Contribution to journalArticle

Tsai, CH, Hsu, HS, Wang, LS, Wang, HW, Wu, YC, Hsieh, CC, Huang, BS, Hsu, WH & Huang, MH 2003, 'Surgical results of squamous cell carcinoma of the esophagus in young patients', Journal of the Chinese Medical Association, vol. 66, no. 5, pp. 288-293.
Tsai CH, Hsu HS, Wang LS, Wang HW, Wu YC, Hsieh CC et al. Surgical results of squamous cell carcinoma of the esophagus in young patients. Journal of the Chinese Medical Association. 2003 May 1;66(5):288-293.
Tsai, Chien H. ; Hsu, Han Shui ; Wang, Liang Shun ; Wang, Hao W. ; Wu, Yu Chung ; Hsieh, Chih Cheng ; Huang, Biing Shiun ; Hsu, Wen H. ; Huang, Min Hsiung. / Surgical results of squamous cell carcinoma of the esophagus in young patients. In: Journal of the Chinese Medical Association. 2003 ; Vol. 66, No. 5. pp. 288-293.
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abstract = "Background. Squamous cell carcinoma of the esophagus (ESCC) is one of the ten most common cancers in Taiwan. Surgical resection is the mainstay of the treatment. Young patients with ESCC are reported to have poor surgical outcome. This retrospective and comparative study is to evaluate the clinicopathologic difference and survival between young and elderly patients. Methods. From January 1985 to December 2000, totally 797 patients with esophageal cancer received esophagectomy with reconstruction at our institution. Among them, 12 patients who received neoadjuvant concurrent chemo-radiotherapy followed by esophagectomy were excluded from this study. The other 785 patients were divided into two groups. Group I included 67 patients aged 50 or younger (8.5{\%}) and group II included 718 patients aged over 50 years (91.5{\%}). The clinical data were collected by chart review and follow-up data were collected through outpatient department record or telephone contact. These two groups were analyzed and compared regarding sex ratio, exposure to tobacco or alcohol, surgical mortality rate and 5-year survival rate. Results. There was no difference in gender distribution between young and old patients groups. More patients in the young patients group had the habits of alcohol and tobacco consumption than in the elder patients group. The surgical (30-day) mortality was 2.98{\%} in the young patient group, and 5.43{\%} in the elder group. The 5-year survival rate was better in young patients group than in elder patients group but there was no statistical significance. Survival in young patients group was significantly related to TNM staging system. Conclusions. More young patients with ESCC had the habit of smoking and drinking. There was no statistical difference between the groups in clinical variables, surgical mortality and survival. The survival rate was significantly related to the TNM tumor stage.",
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AU - Hsu, Han Shui

AU - Wang, Liang Shun

AU - Wang, Hao W.

AU - Wu, Yu Chung

AU - Hsieh, Chih Cheng

AU - Huang, Biing Shiun

AU - Hsu, Wen H.

AU - Huang, Min Hsiung

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N2 - Background. Squamous cell carcinoma of the esophagus (ESCC) is one of the ten most common cancers in Taiwan. Surgical resection is the mainstay of the treatment. Young patients with ESCC are reported to have poor surgical outcome. This retrospective and comparative study is to evaluate the clinicopathologic difference and survival between young and elderly patients. Methods. From January 1985 to December 2000, totally 797 patients with esophageal cancer received esophagectomy with reconstruction at our institution. Among them, 12 patients who received neoadjuvant concurrent chemo-radiotherapy followed by esophagectomy were excluded from this study. The other 785 patients were divided into two groups. Group I included 67 patients aged 50 or younger (8.5%) and group II included 718 patients aged over 50 years (91.5%). The clinical data were collected by chart review and follow-up data were collected through outpatient department record or telephone contact. These two groups were analyzed and compared regarding sex ratio, exposure to tobacco or alcohol, surgical mortality rate and 5-year survival rate. Results. There was no difference in gender distribution between young and old patients groups. More patients in the young patients group had the habits of alcohol and tobacco consumption than in the elder patients group. The surgical (30-day) mortality was 2.98% in the young patient group, and 5.43% in the elder group. The 5-year survival rate was better in young patients group than in elder patients group but there was no statistical significance. Survival in young patients group was significantly related to TNM staging system. Conclusions. More young patients with ESCC had the habit of smoking and drinking. There was no statistical difference between the groups in clinical variables, surgical mortality and survival. The survival rate was significantly related to the TNM tumor stage.

AB - Background. Squamous cell carcinoma of the esophagus (ESCC) is one of the ten most common cancers in Taiwan. Surgical resection is the mainstay of the treatment. Young patients with ESCC are reported to have poor surgical outcome. This retrospective and comparative study is to evaluate the clinicopathologic difference and survival between young and elderly patients. Methods. From January 1985 to December 2000, totally 797 patients with esophageal cancer received esophagectomy with reconstruction at our institution. Among them, 12 patients who received neoadjuvant concurrent chemo-radiotherapy followed by esophagectomy were excluded from this study. The other 785 patients were divided into two groups. Group I included 67 patients aged 50 or younger (8.5%) and group II included 718 patients aged over 50 years (91.5%). The clinical data were collected by chart review and follow-up data were collected through outpatient department record or telephone contact. These two groups were analyzed and compared regarding sex ratio, exposure to tobacco or alcohol, surgical mortality rate and 5-year survival rate. Results. There was no difference in gender distribution between young and old patients groups. More patients in the young patients group had the habits of alcohol and tobacco consumption than in the elder patients group. The surgical (30-day) mortality was 2.98% in the young patient group, and 5.43% in the elder group. The 5-year survival rate was better in young patients group than in elder patients group but there was no statistical significance. Survival in young patients group was significantly related to TNM staging system. Conclusions. More young patients with ESCC had the habit of smoking and drinking. There was no statistical difference between the groups in clinical variables, surgical mortality and survival. The survival rate was significantly related to the TNM tumor stage.

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KW - Squamous cell carcinoma

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