Surface characterization and thermomechanical behavior of nanostructured-gold layer for biomedical applications

Chi Ming Wu, Yi Jung Lu, Shyuan Yow Chen, Shih Cheng Wen, Chia Hung Wu, Pei Bang Liao, Keng Liang Ou, Hsin Hua Chou

Research output: Contribution to journalArticle

Abstract

The microstructure and surface properties of the optimal nanostructured-gold (ONG) film were characterized using scanning electron microscopy, transmission electron microscopy, X-ray diffraction, nanoindentation and static contact angle evaluation in the present study. A three-dimensional model of human liver was reconstructed using magnetic resonance imaging to simulate the thermomechanical performance of the ONG film by means of finite element model analysis. Moreover, a monopolar electrosurgical unit equipped with needle type uncoated stainless steel (U-SS) and ONG film coated stainless steel (ONG-SS) electrodes was used to investigate the thermal distribution in the liver of rats. Experimental results showed that the temperature decreased significantly when using the ONG-SS electrode. The ONG-SS electrode also created a relatively small thermal injury area and lateral thermal effect. Furthermore, thermography indicated that the ONG-SS electrode exhibited a significantly lower surgical temperature as compared with the U-SS electrode during electrosurgery process in rats. Therefore, it could be demonstrated that the ONG-SS electrode is a promising biomedical device for reducing excessive thermal injury and decreasing adherence tissue in electrosurgery.

Original languageEnglish
Pages (from-to)1114-1120
Number of pages7
JournalJournal of Alloys and Compounds
Volume782
DOIs
Publication statusPublished - Apr 25 2019

Keywords

  • Finite element model analysis
  • Microstructure
  • Nanostructured-gold coating
  • Surface modification

ASJC Scopus subject areas

  • Mechanics of Materials
  • Mechanical Engineering
  • Metals and Alloys
  • Materials Chemistry

Fingerprint Dive into the research topics of 'Surface characterization and thermomechanical behavior of nanostructured-gold layer for biomedical applications'. Together they form a unique fingerprint.

  • Cite this