Supraclavicular lymph node metastases in cervical cancer

J. T. Qiu, K. C. Ho, C. H. Lai, T. C. Yen, Y. T. Huang, A. Chao, T. C. Chang

Research output: Contribution to journalReview articlepeer-review

29 Citations (Scopus)

Abstract

Purpose of investigation: To evaluate the outcome and prognostic factors of patients with supraclavicular lymph node (SCLN) involvement at primary diagnosis. Methods: We reviewed the medical records of cervical cancer patients primarily treated at Chang Gung Memorial Hospital between 1987 and 2005. Thirty-three patients with histologically confirmed SCLN metastasis at primary diagnosis were eligible for analysis. Clinical and pathological features were analyzed for association with outcome. Results: The 3- and 5-year survival rates of patients with SCLN metastasis were 16.5% and 16.5%, respectively. Multivariate analysis showed the serum level of squamous cell carcinoma antigen (SCC-Ag) < 15 ng/ml at initial diagnosis (p = 0.021) and staging/restaging including [18F] fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) (p = 0.006) to be associated with a better prognosis. Conclusion: Primary SCLN metastasis in cervical cancer is not incurable. The benefit from PET findings might help in selecting appropriate patients for curative primary and/or salvage treatment.

Original languageEnglish
Pages (from-to)33-38
Number of pages6
JournalEuropean Journal of Gynaecological Oncology
Volume28
Issue number1
Publication statusPublished - 2007
Externally publishedYes

Keywords

  • Cervical cancer
  • FDG-PET
  • Prognostic factor
  • Supraclavicular lymph node

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynaecology

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