Abstract
Radiation-induced oral mucositis is a restricting factor while treating head and neck cancers. It is well known that radiation therapy (R/T) often been interruped while oral mucositis aggravated. To study if Beclomethasone dipropionate an effective drug in the suppression of radiation mucositis. Fifty untreated nasopharyngeal cancer (NPC) patients were randomized into experimental group: (25 NPC patients used Salcoat Cap 50 μg QD) and controlled group (25 NPC patients use Dexaltin l20μg QD). Local treatment have been applied to all patients since the 6th time of R/T. The efficacy was evaluated by 1. Onset and degree of pain sensation of mucositis. 2. Onset and sites of mucositis. 3. Onset and degree of mucositis. 4. Disappearance time of pain sensation and mucositis.
Salcoat is superior to Dexaltin for relief the degree of pain sensation (P＜0.05), time for relief of pain sensation (P＜0.01) and time for recovery of mucositis (P＜0.001).
Salcoat is superior to Dexaltin for relief the degree of pain sensation (P＜0.05), time for relief of pain sensation (P＜0.01) and time for recovery of mucositis (P＜0.001).
| Translated title of the contribution | Suppression of Radiation Mucositis in Nasopharyngeal Cancer Patients: A Randomized Study of Local Application-Salcoat Versus Dexaltin |
|---|---|
| Original language | Chinese (Traditional) |
| Pages (from-to) | 101-104 |
| Number of pages | 4 |
| Journal | 放射治療與腫瘤學 |
| Volume | 3 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1996 |
| Externally published | Yes |
Keywords
- Salcoat
- Nasopharyngeal cancers
- Radiation therapy
- Mucositis