18F-fluorodeoxyglucose positron emission tomography for the initial evaluation and monitoring of therapeutic response in bilateral adrenal histoplasmosis

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18F-fluorodeoxyglucose positron emission tomography (FDG-PET) of a 74-year-old man showed high FDG uptake in bilateral adrenal histoplasmosis. Four months after the administration of an appropriate antifungal treatment, we observed a significant decrease in FDG uptake into the lesions, with a 40% reduction in activity (maximal standardized uptake value). This imaging result indicated partial resolution of the disease and was consistent with clinical outcome. Our study results suggest that FDG-PET is a useful modality for initial whole-body evaluation, selection of an appropriate antifungal treatment regimen, and monitoring of therapeutic response in bilateral adrenal histoplasmosis.

Original languageEnglish
Pages (from-to)791-793
Number of pages3
JournalClinical Imaging
Issue number4
Publication statusPublished - Jul 2013



  • Adrenal gland
  • Histoplasmosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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