Suitability of Fetal Tissues From Spontaneous Abortions and From Ectopic Pregnancies for Transplantation

D. Ware Branch, Lee Ducat, Alan Fantel, Walter C. Low, Feng C. Zhou, Delbert H. Dayton, Thomas J. Gill, Sharon Bledsoe, Yung Hsiao Chiang, Sonny K. Chong, Bryan E. Hainline, Stephen A. Heifetz, Debra Kahlenbeck, Qinyuan Low, Lillie Mae Padilla, Catherine Palmer, Daniel Peavy, Bruce Blazer, Jeff Blount, Judy ChristiansonGayl Chrysler, John Conrad, Laura Coultrip, Peter D'ascoli, Ted Eastlund, Jeanne Forbes, Tom Gasser, Mark Hirschel, Warren Kearney, Takeshi Kondoh, Ying Jie, Sandy Maynard, Jeff Miller, Beverly Norris, Takashi Okagaki, Anne Peterson, Lisa Pundt, Ranjita Sengupta, Catherine Verfaillie, Beth Virnig, Kathy Weese, Preston Williams, Kelly Feil, Alberto Hayek, Virginia Lee, Michael K. Mccormack, F. Arthur Mcmorris, Susan Shen Schwarz, John Q. Trojanowski, Janice L B Byrne, Kenneth Ward, Sharon Hillier, Molly Hogan, Raj Kapur, Marijane Krohn, Kathy Leppig, Julie Mason, Beth Mueller, Helen Newman Gage, Thomas Norwood, Ted Rigley, Soe Soe Thwin, Tara Vick

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Abstract

To assess the potential availability and utility of fetal tissues obtained from spontaneous abortions and from ectopic pregnancies for human transplantation therapy. —Tissue collection and analysis by personnel skilled in tissue banking. —Procurement programs in five tissue banks located in diverse geographical areas that are funded by the National Institutes of Health. —All women entering obstetric clinics during 1993 who consented to participate in the study. —None. —Evaluation of the products of conception by standard developmental, histological, microbiological, and cytogenetic criteria. —From 22235 obstetric admissions, 1250 spontaneously aborted embryos and 247 products of ectopic pregnancies were obtained. Of these, seven embryos (0.5%) were potentially useful for human transplantation therapy. —Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy.

Original languageEnglish
Pages (from-to)66-68
Number of pages3
JournalJournal of the American Medical Association
Volume273
Issue number1
DOIs
Publication statusPublished - 1995
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ware Branch, D., Ducat, L., Fantel, A., Low, W. C., Zhou, F. C., Dayton, D. H., Gill, T. J., Bledsoe, S., Chiang, Y. H., Chong, S. K., Hainline, B. E., Heifetz, S. A., Kahlenbeck, D., Low, Q., Padilla, L. M., Palmer, C., Peavy, D., Blazer, B., Blount, J., ... Vick, T. (1995). Suitability of Fetal Tissues From Spontaneous Abortions and From Ectopic Pregnancies for Transplantation. Journal of the American Medical Association, 273(1), 66-68. https://doi.org/10.1001/jama.1995.03520250082038