Sudden sensorineural hearing loss associated with chronic periodontitis

A population-based study

Chuan Song Wu, Tzong Hann Yang, Herng Ching Lin, Jau Jiuan Sheu, Dachen Chu

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective: Although plenty of researchers have reported systemic effects originating from chronic periodontitis (CP) on potentially distal inflammatory processes, such as those leading to coronary heart disease, cerebrovascular disease, and cancer, no study has reported the association between CP and sudden sensorineural hearing loss (SSNHL). The present study explored the association between CP and SSNHL using a large, population-based dataset in Taiwan. Study Design: A case-control study. Setting: Taiwan. Patients: We used administrative claims data from the Taiwan National Health Insurance program to identify 2,436 subjects with SSNHL and to randomly select 7,308 controls. MAIN OUTCOME MEASURES: A conditional logistic regression analysis was conducted to calculate the odds ratio (OR) for having been previously diagnosed with CP between cases and controls. Results: In total, 1,663 (17.1%) of the 9,744 sampled subjects had received a CP diagnosis before the index date; 520 (21.4%) were cases and 1143 (15.6%) were controls. The χ test suggested that there was a significant difference in the prevalence of previous SSNHL between cases and controls (p <0.001). The conditional logistic regression revealed after adjusting for hypertension, diabetes, hyperlipidemia, renal disease, coronary heart disease, obesity, and stroke, the OR of having previously received a CP diagnosis among cases was 1.44 (95% CI = 1.29∼1.63) that of controls. Conclusion: This study found that SSNHL was significantly associated with a previous diagnosis of CP. Further prospective studies are warranted to confirm our findings and clarify the underlying pathomechanism.

Original languageEnglish
Pages (from-to)1380-1384
Number of pages5
JournalOtology and Neurotology
Volume34
Issue number8
DOIs
Publication statusPublished - Oct 2013

Fingerprint

Sudden Hearing Loss
Chronic Periodontitis
Sensorineural Hearing Loss
Population
Taiwan
National Health Programs
Coronary Disease
Logistic Models
Odds Ratio
Cerebrovascular Disorders
Hyperlipidemias
Case-Control Studies
Obesity
Stroke
Regression Analysis
Research Personnel
Prospective Studies
Hypertension
Kidney

Keywords

  • Acute myocardial infarction
  • Epidemiology
  • Sudden sensorineural hearing loss

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Clinical Neurology
  • Sensory Systems
  • Medicine(all)

Cite this

Sudden sensorineural hearing loss associated with chronic periodontitis : A population-based study. / Wu, Chuan Song; Yang, Tzong Hann; Lin, Herng Ching; Sheu, Jau Jiuan; Chu, Dachen.

In: Otology and Neurotology, Vol. 34, No. 8, 10.2013, p. 1380-1384.

Research output: Contribution to journalArticle

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