Abstract
Pain severity and sleep are associated with cognitive performance in patients with fibromyalgia. This study examined whether sleep mediates the relationships of pain severity with psychomotor vigilance and attention in patients with fibromyalgia by analysing 80 patients with fibromyalgia. Cognitive performance, pain severity and sleep parameters were determined using the Psychomotor Vigilance Task, Brief Pain Inventory–Short Form and sleep diaries of seven consecutive nights, respectively. The patients’ demographic data were analysed for potential confounding factors. After adjustment for these confounders, a series of regression analyses was performed to examine the mediating role of sleep. The results indicated that higher pain severity was strongly associated with poorer sustained attention and lower sleep quality, the total effects of pain severity on psychomotor vigilance and attention were significant (c path: β = 0.23, p = 0.04), and pain severity was a significant sleep quality predictor (a path: β = −0.33, p < 0.01). When sleep quality was entered into the regression model (a × b path), the effects of pain severity on psychomotor vigilance and attention became non-significant (c′ path: β = 0.15, p = 0.20) after adjustment of age, indicating a complete mediating effect of sleep quality in the pain severity–cognitive performance relationship. In conclusion, sleep quality mediates the pain severity–cognitive performance relationship: pain affects sleep quality, which in turn impairs sustained attention. Our findings provide further insight into the processes underlying the relationship between pain and poor cognitive function. Improved sleep quality may offset the detrimental effects of pain on sustained attention.
| Original language | English |
|---|---|
| Article number | e12843 |
| Journal | Journal of Sleep Research |
| DOIs | |
| Publication status | Published - Mar 28 2019 |
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Keywords
- cognitive performance
- fibromyalgia
- pain severity
- sleep quality
ASJC Scopus subject areas
- Cognitive Neuroscience
- Behavioral Neuroscience
Cite this
Subjective sleep quality as a mediator in the relationship between pain severity and sustained attention performance in patients with fibromyalgia. / Fang, Su Chen; Wu, Yu Lin; Chen, Shih Ching; Teng, Hao Wen; Tsai, Pei Shan.
In: Journal of Sleep Research, 28.03.2019.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Subjective sleep quality as a mediator in the relationship between pain severity and sustained attention performance in patients with fibromyalgia
AU - Fang, Su Chen
AU - Wu, Yu Lin
AU - Chen, Shih Ching
AU - Teng, Hao Wen
AU - Tsai, Pei Shan
PY - 2019/3/28
Y1 - 2019/3/28
N2 - Pain severity and sleep are associated with cognitive performance in patients with fibromyalgia. This study examined whether sleep mediates the relationships of pain severity with psychomotor vigilance and attention in patients with fibromyalgia by analysing 80 patients with fibromyalgia. Cognitive performance, pain severity and sleep parameters were determined using the Psychomotor Vigilance Task, Brief Pain Inventory–Short Form and sleep diaries of seven consecutive nights, respectively. The patients’ demographic data were analysed for potential confounding factors. After adjustment for these confounders, a series of regression analyses was performed to examine the mediating role of sleep. The results indicated that higher pain severity was strongly associated with poorer sustained attention and lower sleep quality, the total effects of pain severity on psychomotor vigilance and attention were significant (c path: β = 0.23, p = 0.04), and pain severity was a significant sleep quality predictor (a path: β = −0.33, p < 0.01). When sleep quality was entered into the regression model (a × b path), the effects of pain severity on psychomotor vigilance and attention became non-significant (c′ path: β = 0.15, p = 0.20) after adjustment of age, indicating a complete mediating effect of sleep quality in the pain severity–cognitive performance relationship. In conclusion, sleep quality mediates the pain severity–cognitive performance relationship: pain affects sleep quality, which in turn impairs sustained attention. Our findings provide further insight into the processes underlying the relationship between pain and poor cognitive function. Improved sleep quality may offset the detrimental effects of pain on sustained attention.
AB - Pain severity and sleep are associated with cognitive performance in patients with fibromyalgia. This study examined whether sleep mediates the relationships of pain severity with psychomotor vigilance and attention in patients with fibromyalgia by analysing 80 patients with fibromyalgia. Cognitive performance, pain severity and sleep parameters were determined using the Psychomotor Vigilance Task, Brief Pain Inventory–Short Form and sleep diaries of seven consecutive nights, respectively. The patients’ demographic data were analysed for potential confounding factors. After adjustment for these confounders, a series of regression analyses was performed to examine the mediating role of sleep. The results indicated that higher pain severity was strongly associated with poorer sustained attention and lower sleep quality, the total effects of pain severity on psychomotor vigilance and attention were significant (c path: β = 0.23, p = 0.04), and pain severity was a significant sleep quality predictor (a path: β = −0.33, p < 0.01). When sleep quality was entered into the regression model (a × b path), the effects of pain severity on psychomotor vigilance and attention became non-significant (c′ path: β = 0.15, p = 0.20) after adjustment of age, indicating a complete mediating effect of sleep quality in the pain severity–cognitive performance relationship. In conclusion, sleep quality mediates the pain severity–cognitive performance relationship: pain affects sleep quality, which in turn impairs sustained attention. Our findings provide further insight into the processes underlying the relationship between pain and poor cognitive function. Improved sleep quality may offset the detrimental effects of pain on sustained attention.
KW - cognitive performance
KW - fibromyalgia
KW - pain severity
KW - sleep quality
UR - http://www.scopus.com/inward/record.url?scp=85063611003&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85063611003&partnerID=8YFLogxK
U2 - 10.1111/jsr.12843
DO - 10.1111/jsr.12843
M3 - Article
JO - Journal of Sleep Research
JF - Journal of Sleep Research
SN - 0962-1105
M1 - e12843
ER -