Studies on antiulcer Chinese herbs (1)

Ming Hsuan Lin, Shih Yuan Hsu, Ming Jer Sheih, Tzeng Fu Chen, Chau Yang Chen

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Abstract

We systematically investigated the effects of five Chinese herbal drugs (Atractylodes macrocephala Koidz, Paeonia lactiflora Pall., Citrus aurantium L., Alpinia officinarum Hance and Magnolia officinalis Rehd. et Wils.) available in Taiwan on experimental gastric ulcers. Crude water extracts were tested against five experimental acute ulcers (stress ulcers, Shay's ulcers, aspirin- induced gastric ulcers, mepirizole- induced duodenal lesions and cysteamine- induced duodenal lesions) and two experimental chronic ulcers (acetic acid- induced and thermocautery ulcers). Atractylodes macrocephala possessed significant protective effects against acute and chronic experimental ulcers in male Wistar rats. Alpinia officinarum and the other extracts also displayed statistically significant activities. These Chinese herbal drugs therefore possess antisecretory and anti-ulcer activities.

Original languageEnglish
Pages (from-to)55-66
Number of pages12
JournalChinese Pharmaceutical Journal
Volume50
Issue number1
Publication statusPublished - Feb 1998

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Keywords

  • Antiulcer agent
  • Experimental gastric ulcers
  • Ulcer protective effects

ASJC Scopus subject areas

  • Bioengineering
  • Pharmaceutical Science

Cite this

Lin, M. H., Hsu, S. Y., Sheih, M. J., Chen, T. F., & Chen, C. Y. (1998). Studies on antiulcer Chinese herbs (1). Chinese Pharmaceutical Journal, 50(1), 55-66.