Structural characteristics and antioxidative capability of the soluble polysaccharides present in dictyophora indusiata (Vent. Ex Pers.) fish phallaceae

Chiu Lan Hsieh, Yaw Bee Ker, Kuan Chou Chen, Chiung Chi Peng, Robert Y. Peng

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Dictyophora indusiata (Vent. ex Pers.) Fish Phallaceae (Chinese name Zhu-Sn, the bamboo fungi) has been used as a medicinal mushroom to treat many inflammatory, gastric and neural diseases since 618AD in China. We hypothesize that the soluble polysaccharides (SP) present in D. indusiata and their monosaccharide profiles can act as an important role affecting the antioxidative capability, which in turn would influence the biological activity involving anti-inflammatory, immune enhancing and anticancer. We obtained six SP fractions and designated them as D1, a galactoglucan; D2, a galactan; D3, the isoelectrically precipitated riboglucan from 2% NaOH; D4, a myoinositol; D5 and D6, the mannogalactans. The total SP accounted for 37.44% w/w, their molecular weight (MW) ranged within 8014656kDa. D3, having the smallest MW 801kDa, exhibited the most potent scavenging effect against the diphenyl-picrylhydrazyl, OH(), and O 2 radicals, yielding IC50 values 0.11, 1.02 and 0.64mgmL(1), respectively. Thus we have confirmed our hypothesis that the bioactivity of D. indusiata is related in majority, if not entirely, to its soluble polysaccharide type regarding the MW and monosaccharide profiles.

Original languageEnglish
Article number396013
JournalEvidence-based Complementary and Alternative Medicine
Volume2011
DOIs
Publication statusPublished - 2011
Externally publishedYes

Fingerprint

Polysaccharides
Fishes
Monosaccharides
Molecular Weight
Galactans
Stomach Diseases
Agaricales
Inositol
Inhibitory Concentration 50
Names
China
Fungi
Anti-Inflammatory Agents

ASJC Scopus subject areas

  • Complementary and alternative medicine

Cite this

@article{417ce5445150457d82460ffb78229a92,
title = "Structural characteristics and antioxidative capability of the soluble polysaccharides present in dictyophora indusiata (Vent. Ex Pers.) fish phallaceae",
abstract = "Dictyophora indusiata (Vent. ex Pers.) Fish Phallaceae (Chinese name Zhu-Sn, the bamboo fungi) has been used as a medicinal mushroom to treat many inflammatory, gastric and neural diseases since 618AD in China. We hypothesize that the soluble polysaccharides (SP) present in D. indusiata and their monosaccharide profiles can act as an important role affecting the antioxidative capability, which in turn would influence the biological activity involving anti-inflammatory, immune enhancing and anticancer. We obtained six SP fractions and designated them as D1, a galactoglucan; D2, a galactan; D3, the isoelectrically precipitated riboglucan from 2{\%} NaOH; D4, a myoinositol; D5 and D6, the mannogalactans. The total SP accounted for 37.44{\%} w/w, their molecular weight (MW) ranged within 8014656kDa. D3, having the smallest MW 801kDa, exhibited the most potent scavenging effect against the diphenyl-picrylhydrazyl, OH(), and O 2 radicals, yielding IC50 values 0.11, 1.02 and 0.64mgmL(1), respectively. Thus we have confirmed our hypothesis that the bioactivity of D. indusiata is related in majority, if not entirely, to its soluble polysaccharide type regarding the MW and monosaccharide profiles.",
author = "Hsieh, {Chiu Lan} and Ker, {Yaw Bee} and Chen, {Kuan Chou} and Peng, {Chiung Chi} and Peng, {Robert Y.}",
year = "2011",
doi = "10.1093/ecam/neq041",
language = "English",
volume = "2011",
journal = "Evidence-based Complementary and Alternative Medicine",
issn = "1741-427X",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - Structural characteristics and antioxidative capability of the soluble polysaccharides present in dictyophora indusiata (Vent. Ex Pers.) fish phallaceae

AU - Hsieh, Chiu Lan

AU - Ker, Yaw Bee

AU - Chen, Kuan Chou

AU - Peng, Chiung Chi

AU - Peng, Robert Y.

PY - 2011

Y1 - 2011

N2 - Dictyophora indusiata (Vent. ex Pers.) Fish Phallaceae (Chinese name Zhu-Sn, the bamboo fungi) has been used as a medicinal mushroom to treat many inflammatory, gastric and neural diseases since 618AD in China. We hypothesize that the soluble polysaccharides (SP) present in D. indusiata and their monosaccharide profiles can act as an important role affecting the antioxidative capability, which in turn would influence the biological activity involving anti-inflammatory, immune enhancing and anticancer. We obtained six SP fractions and designated them as D1, a galactoglucan; D2, a galactan; D3, the isoelectrically precipitated riboglucan from 2% NaOH; D4, a myoinositol; D5 and D6, the mannogalactans. The total SP accounted for 37.44% w/w, their molecular weight (MW) ranged within 8014656kDa. D3, having the smallest MW 801kDa, exhibited the most potent scavenging effect against the diphenyl-picrylhydrazyl, OH(), and O 2 radicals, yielding IC50 values 0.11, 1.02 and 0.64mgmL(1), respectively. Thus we have confirmed our hypothesis that the bioactivity of D. indusiata is related in majority, if not entirely, to its soluble polysaccharide type regarding the MW and monosaccharide profiles.

AB - Dictyophora indusiata (Vent. ex Pers.) Fish Phallaceae (Chinese name Zhu-Sn, the bamboo fungi) has been used as a medicinal mushroom to treat many inflammatory, gastric and neural diseases since 618AD in China. We hypothesize that the soluble polysaccharides (SP) present in D. indusiata and their monosaccharide profiles can act as an important role affecting the antioxidative capability, which in turn would influence the biological activity involving anti-inflammatory, immune enhancing and anticancer. We obtained six SP fractions and designated them as D1, a galactoglucan; D2, a galactan; D3, the isoelectrically precipitated riboglucan from 2% NaOH; D4, a myoinositol; D5 and D6, the mannogalactans. The total SP accounted for 37.44% w/w, their molecular weight (MW) ranged within 8014656kDa. D3, having the smallest MW 801kDa, exhibited the most potent scavenging effect against the diphenyl-picrylhydrazyl, OH(), and O 2 radicals, yielding IC50 values 0.11, 1.02 and 0.64mgmL(1), respectively. Thus we have confirmed our hypothesis that the bioactivity of D. indusiata is related in majority, if not entirely, to its soluble polysaccharide type regarding the MW and monosaccharide profiles.

UR - http://www.scopus.com/inward/record.url?scp=80052723845&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052723845&partnerID=8YFLogxK

U2 - 10.1093/ecam/neq041

DO - 10.1093/ecam/neq041

M3 - Article

C2 - 21799678

AN - SCOPUS:80052723845

VL - 2011

JO - Evidence-based Complementary and Alternative Medicine

JF - Evidence-based Complementary and Alternative Medicine

SN - 1741-427X

M1 - 396013

ER -