Streptococcal toxic shock syndrome in southern Taiwan

S. R. Wann, M. Y. Yen, Y. S. Chen, J. H. Wang, W. K. Huang, T. S. Huang, J. H. Wang, Y. C. Liu, D. L. Cheng

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This report outlies our experience with streptococcal toxic shock syndrome (STSS) at the Veterans General Hospital-Kaohsiung during the period October 1990 to November 1993. Group A streptococci were isolated from blood or normally sterile tissue in association with hypotension and multi-organ failure in the eight cases studied. A primary focus of infection was identified in seven cases, including pneumonia (1), septic arthritis (1) and soft-tissue infections (5). The remaining patient suffered from hyperglycemic hyperosmolar non-ketotic coma and Group A streptococcal bacteremia, without an obvious focus of infection. There were four cases of bacteremia. Clinical complications included acute renal failure in all eight cases, disseminated intravascular coagulation in five cases, liver involvement in two cases, adult respiratory distress syndrome in one case and soft-tissue necrosis in five cases. All isolates were sensitive to penicillin, and most patients were treated with intravenous penicillin G, with or without other antibiotics (gentamicin or clindamycin). Of the six patients with soft-tissue infection, two underwent amputation of the infected limb, and one patient underwent sono-guided pigtail drainage of psoas muscle abscess. Three of the patients died. STSS may be uncommon in Taiwan, but it is not rare. Early recognition of STSS (facilitated by Gram stain and culture), prompt debridement and drainage, and adequate antibiotic treatment with penicillin or clindamycin, or both, are necessary for control of such lethal infections.

Original languageEnglish
Pages (from-to)172-177
Number of pages6
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume94
Issue number4
Publication statusPublished - 1995
Externally publishedYes

Fingerprint

Septic Shock
Taiwan
Soft Tissue Infections
Clindamycin
Bacteremia
Penicillins
Drainage
Infection
Psoas Abscess
Psoas Muscles
Anti-Bacterial Agents
Veterans Hospitals
Infectious Arthritis
Penicillin G
Disseminated Intravascular Coagulation
Adult Respiratory Distress Syndrome
Debridement
Coma
Gentamicins
Streptococcus

Keywords

  • group A streptococcus
  • streptococcal toxic shock syndrome
  • Streptococcus pyogenes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Wann, S. R., Yen, M. Y., Chen, Y. S., Wang, J. H., Huang, W. K., Huang, T. S., ... Cheng, D. L. (1995). Streptococcal toxic shock syndrome in southern Taiwan. Journal of the Formosan Medical Association = Taiwan yi zhi, 94(4), 172-177.

Streptococcal toxic shock syndrome in southern Taiwan. / Wann, S. R.; Yen, M. Y.; Chen, Y. S.; Wang, J. H.; Huang, W. K.; Huang, T. S.; Wang, J. H.; Liu, Y. C.; Cheng, D. L.

In: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 94, No. 4, 1995, p. 172-177.

Research output: Contribution to journalArticle

Wann, SR, Yen, MY, Chen, YS, Wang, JH, Huang, WK, Huang, TS, Wang, JH, Liu, YC & Cheng, DL 1995, 'Streptococcal toxic shock syndrome in southern Taiwan', Journal of the Formosan Medical Association = Taiwan yi zhi, vol. 94, no. 4, pp. 172-177.
Wann SR, Yen MY, Chen YS, Wang JH, Huang WK, Huang TS et al. Streptococcal toxic shock syndrome in southern Taiwan. Journal of the Formosan Medical Association = Taiwan yi zhi. 1995;94(4):172-177.
Wann, S. R. ; Yen, M. Y. ; Chen, Y. S. ; Wang, J. H. ; Huang, W. K. ; Huang, T. S. ; Wang, J. H. ; Liu, Y. C. ; Cheng, D. L. / Streptococcal toxic shock syndrome in southern Taiwan. In: Journal of the Formosan Medical Association = Taiwan yi zhi. 1995 ; Vol. 94, No. 4. pp. 172-177.
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