Abstract
We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.
| Original language | English |
|---|---|
| Journal | Acta Paediatrica Taiwanica |
| Volume | 48 |
| Issue number | 3 |
| Publication status | Published - May 2007 |
Keywords
- Hyperbilirubinemia
- Sepsis
- Steroid
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
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Wang, J. L., Ou, T. Y., Chen, C. N., & Shen, E. Y. (2007). Steroid use in sepsis-induced conjugated hyperbilirubinemia: Report of one case. Acta Paediatrica Taiwanica, 48(3).