Steroid use in sepsis-induced conjugated hyperbilirubinemia: Report of one case

Jinn Li Wang, Tsong Yih Ou, Chun Nan Chen, Ein Yiao Shen

Research output: Contribution to journalArticle

Abstract

We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.

Original languageEnglish
JournalActa Paediatrica Taiwanica
Volume48
Issue number3
Publication statusPublished - May 2007

Keywords

  • Hyperbilirubinemia
  • Sepsis
  • Steroid

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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