Abstract
We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.
| Original language | English |
|---|---|
| Journal | Acta Paediatrica Taiwanica |
| Volume | 48 |
| Issue number | 3 |
| Publication status | Published - May 2007 |
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Keywords
- Hyperbilirubinemia
- Sepsis
- Steroid
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Steroid use in sepsis-induced conjugated hyperbilirubinemia : Report of one case. / Wang, Jinn Li; Ou, Tsong Yih; Chen, Chun Nan; Shen, Ein Yiao.
In: Acta Paediatrica Taiwanica, Vol. 48, No. 3, 05.2007.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Steroid use in sepsis-induced conjugated hyperbilirubinemia
T2 - Report of one case
AU - Wang, Jinn Li
AU - Ou, Tsong Yih
AU - Chen, Chun Nan
AU - Shen, Ein Yiao
PY - 2007/5
Y1 - 2007/5
N2 - We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.
AB - We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.
KW - Hyperbilirubinemia
KW - Sepsis
KW - Steroid
UR - http://www.scopus.com/inward/record.url?scp=34548811919&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548811919&partnerID=8YFLogxK
M3 - Article
C2 - 17912987
AN - SCOPUS:34548811919
VL - 48
JO - Pediatrics and Neonatology
JF - Pediatrics and Neonatology
SN - 1875-9572
IS - 3
ER -