Steroid use in sepsis-induced conjugated hyperbilirubinemia

Report of one case

Jinn Li Wang, Tsong Yih Ou, Chun Nan Chen, Ein Yiao Shen

Research output: Contribution to journal › Article

Abstract

We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.

Original languageEnglish
JournalActa Paediatrica Taiwanica
Volume48
Issue number3
Publication statusPublished - May 2007

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Hyperbilirubinemia
Sepsis
Steroids
Bilirubin
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Hydrocortisone
Escherichia coli
Anti-Bacterial Agents
Therapeutics

Keywords

  • Hyperbilirubinemia
  • Sepsis
  • Steroid

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Wang, J. L., Ou, T. Y., Chen, C. N., & Shen, E. Y. (2007). Steroid use in sepsis-induced conjugated hyperbilirubinemia: Report of one case. Acta Paediatrica Taiwanica, 48(3).

Steroid use in sepsis-induced conjugated hyperbilirubinemia : Report of one case. / Wang, Jinn Li; Ou, Tsong Yih; Chen, Chun Nan; Shen, Ein Yiao.

In: Acta Paediatrica Taiwanica, Vol. 48, No. 3, 05.2007.

Research output: Contribution to journal › Article

Wang, JL, Ou, TY, Chen, CN & Shen, EY 2007, 'Steroid use in sepsis-induced conjugated hyperbilirubinemia: Report of one case', Acta Paediatrica Taiwanica, vol. 48, no. 3.
Wang JL, Ou TY, Chen CN, Shen EY. Steroid use in sepsis-induced conjugated hyperbilirubinemia: Report of one case. Acta Paediatrica Taiwanica. 2007 May;48(3).
Wang, Jinn Li ; Ou, Tsong Yih ; Chen, Chun Nan ; Shen, Ein Yiao. / Steroid use in sepsis-induced conjugated hyperbilirubinemia : Report of one case. In: Acta Paediatrica Taiwanica. 2007 ; Vol. 48, No. 3.
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