Stage migration influences on stage-specific survival comparison between D1 and D3 gastric cancer surgeries

C. W. Wu, C. A. Hsiung, S. S. Lo, M. C. Hsieh, J. H. Chen, A. F. Li, W. Y. Lui, J. Whang-Peng

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Aims. We evaluate the influency stage migration in a randomised trial comparing D1 (N 1 lymphadenectomy) and D3 (N 1, 2 and 3 lymphadenectomy) dissections. Methods. Two hundred and thirteen curatively resected pati ents were analysed, with this TNM data. Results. After applying D3 patients' data according to simulated D1 staging, D3 resections were associated with up-staging to N2-3 levels in 8% of patients according to the N stage. The likelihood of N-status migration increased with increasing depth of invasion into the gastric wall. The increases in the calculated survival rate after stage migration on known 5-year survival rates were: 2% in stage IB, 1% in stage II, 4% in stage IIIA, and 1% in stage IIIB. Conclusions. Stage mi gration secondary to meticulous lymph node dissection affects stage-specific survival rates. True therapeutic survival benefit of D3 resection can only be assessed in this context.

Original languageEnglish
Pages (from-to)153-157
Number of pages5
JournalEuropean Journal of Surgical Oncology
Volume31
Issue number2
DOIs
Publication statusPublished - Mar 1 2005
Externally publishedYes

Fingerprint

Lymph Node Excision
Stomach Neoplasms
Survival Rate
Survival
Dissection
Stomach
Therapeutics

Keywords

  • Gastric cancer
  • Stage migration
  • Surgical randomised trial

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Stage migration influences on stage-specific survival comparison between D1 and D3 gastric cancer surgeries. / Wu, C. W.; Hsiung, C. A.; Lo, S. S.; Hsieh, M. C.; Chen, J. H.; Li, A. F.; Lui, W. Y.; Whang-Peng, J.

In: European Journal of Surgical Oncology, Vol. 31, No. 2, 01.03.2005, p. 153-157.

Research output: Contribution to journalArticle

Wu, C. W. ; Hsiung, C. A. ; Lo, S. S. ; Hsieh, M. C. ; Chen, J. H. ; Li, A. F. ; Lui, W. Y. ; Whang-Peng, J. / Stage migration influences on stage-specific survival comparison between D1 and D3 gastric cancer surgeries. In: European Journal of Surgical Oncology. 2005 ; Vol. 31, No. 2. pp. 153-157.
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