Squamous cell carcinoma arising from a recurrent ischial pressure ulcer: A case report

Chang-Yi Chou, Zheng-Yi Huang, Hao-Yu Chiao, Chi-Yu Wang, Yu-Shan Sun, Shyi-Gen Chen, Tim-Mon Chen, Shun-Cheng Chang

Research output: Contribution to journalArticle

Abstract

Marjolin's ulcer is the malignant transformation of long-standing chronic pressure ulcers and requires prompt diagnosis and treatment. A 46-year-old man with an 8-year history of traumatic spinal injury with paraplegia presented with a recurrent ischial pressure ulcer. The initial ulcer, which developed 6 years earlier, was a Stage IV sacral ulcer. The wound was debrided and pathology showed epithelial hyperplasia, acanthosis, hyperkatosis accompanied by mild inflammation, and fibrosis without any malignant transformation. The lesion was covered with a fasciocutaneous bipedicled flap. Four years later, the patient presented with a similar ulcer in the same location. Histology showed the presence of a well-differentiated squamous cell carcinoma (SCC). Following a wide excision, the lesion was covered with a gluteal maximal V-Y musculocutaneous advancement flap. At last follow-up 14 months postoperatively, there was no evidence of recurrence or metastatic disease. Clinicians must be aware of known risk factors for the development of SCC.
Original languageEnglish
Pages (from-to)48-50
Number of pages3
JournalOstomy Wound Management
Volume61
Issue number2
Publication statusPublished - 2015
Externally publishedYes

Fingerprint

Pressure Ulcer
Ulcer
Squamous Cell Carcinoma
Spinal Injuries
Myocutaneous Flap
Paraplegia
Hyperplasia
Histology
Fibrosis
Pathology
Inflammation
Recurrence
Wounds and Injuries
Therapeutics

Keywords

  • case study
  • Marjolin's ulcer
  • pressure ulcer
  • squamous cell carcinoma

Cite this

Chou, C-Y., Huang, Z-Y., Chiao, H-Y., Wang, C-Y., Sun, Y-S., Chen, S-G., ... Chang, S-C. (2015). Squamous cell carcinoma arising from a recurrent ischial pressure ulcer: A case report. Ostomy Wound Management, 61(2), 48-50.

Squamous cell carcinoma arising from a recurrent ischial pressure ulcer: A case report. / Chou, Chang-Yi; Huang, Zheng-Yi; Chiao, Hao-Yu; Wang, Chi-Yu; Sun, Yu-Shan; Chen, Shyi-Gen; Chen, Tim-Mon; Chang, Shun-Cheng.

In: Ostomy Wound Management, Vol. 61, No. 2, 2015, p. 48-50.

Research output: Contribution to journalArticle

Chou, C-Y, Huang, Z-Y, Chiao, H-Y, Wang, C-Y, Sun, Y-S, Chen, S-G, Chen, T-M & Chang, S-C 2015, 'Squamous cell carcinoma arising from a recurrent ischial pressure ulcer: A case report', Ostomy Wound Management, vol. 61, no. 2, pp. 48-50.
Chou C-Y, Huang Z-Y, Chiao H-Y, Wang C-Y, Sun Y-S, Chen S-G et al. Squamous cell carcinoma arising from a recurrent ischial pressure ulcer: A case report. Ostomy Wound Management. 2015;61(2):48-50.
Chou, Chang-Yi ; Huang, Zheng-Yi ; Chiao, Hao-Yu ; Wang, Chi-Yu ; Sun, Yu-Shan ; Chen, Shyi-Gen ; Chen, Tim-Mon ; Chang, Shun-Cheng. / Squamous cell carcinoma arising from a recurrent ischial pressure ulcer: A case report. In: Ostomy Wound Management. 2015 ; Vol. 61, No. 2. pp. 48-50.
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abstract = "Marjolin's ulcer is the malignant transformation of long-standing chronic pressure ulcers and requires prompt diagnosis and treatment. A 46-year-old man with an 8-year history of traumatic spinal injury with paraplegia presented with a recurrent ischial pressure ulcer. The initial ulcer, which developed 6 years earlier, was a Stage IV sacral ulcer. The wound was debrided and pathology showed epithelial hyperplasia, acanthosis, hyperkatosis accompanied by mild inflammation, and fibrosis without any malignant transformation. The lesion was covered with a fasciocutaneous bipedicled flap. Four years later, the patient presented with a similar ulcer in the same location. Histology showed the presence of a well-differentiated squamous cell carcinoma (SCC). Following a wide excision, the lesion was covered with a gluteal maximal V-Y musculocutaneous advancement flap. At last follow-up 14 months postoperatively, there was no evidence of recurrence or metastatic disease. Clinicians must be aware of known risk factors for the development of SCC.",
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note = "被引用次數:1 Export Date: 21 March 2016 通訊地址: Chou, C.-Y.resident, No. 325, Sec.2, Chenggong Road, Taiwan 參考文獻: Jellouli-Elloumi, A., Kochbati, L., Dhraief, S., Ben Romdhane, K., Maalej, M., Cancers arising from burn scars: 62 cases (2003) Ann Dermatol Venereol., 130 (4), pp. 413-416; Standkard, C.E., Cruse, C.W., Wells, K.E., Karl, R., Chronic pressure ulcer carcinomas (1993) Ann Plast Surg., 30 (3), pp. 274-277; Daya, M., Balakrishan, T., Advanced Marjolin's ulcer of the scalp in a 13-year-old boy treated by excision and free tissue transfer: Case report and review of literature (2009) Indian J Plast Surg., 42 (1), pp. 106-111; Alam, M., Ratner, D., Cutaneous squamous-cell carcinoma (2001) N Engl J Med., 344 (13), pp. 975-983; Kerr-Valentic, M.A., Samimi, K., Rohlen, B.H., Agarwal, J.P., Rockwell, W.B., Marjolin's ulcer: Modern analysis of an ancient problem (2009) Plast Reconstr Surg., 123 (1), pp. 184-191; Mustoe, T., Upton, J., Marcellino, V., Tun, C.J., Rossier, A.B., Hachend, H.J., Carcinoma in chronic pressure sores: A fulminant disease process (1986) Plast Reconstr Surg., 77 (1), pp. 116-121; Knudsen, M.A., Biering-S{\o}rensen, F., Development of Marjolin's ulcer following successful surgical treatment of chronic sacral pressure sore (2008) Spinal Cord., 46 (3), pp. 239-240; Fairbairn, N.G., Hamilton, S.A., Management of marjolin's ulcer in a chronic pressure sore secondary to paraplegia: A radical surgical solution (2011) Int Wound J., 8 (5), pp. 533-536; Tobin, C., Sanger, J.R., Marjolin's ulcers: A case series and literature review (2014) WOUNDS, 26 (9), pp. 248-254; Bozkurt, M., Kapi, E., Kuvat, S.V., Ozekinci, S., Current concepts in the management of Marjolin's ulcers: Outcomes from a standardized treatment protocol in 16 cases (2010) J Burn Care Res., 31 (5), pp. 776-780; Eltorai, I.M., Montroy, R.E., Kobayashi, M., Jakowatz, J., Guttierez, P., Marjolin's ulcer in patients with spinal cord injury (2002) J Spinal Cord Med., 25 (3), pp. 191-196; Grotting, J.C., Bunkis, J., Vasconez, L.O., Pressure sore carcinoma (1987) Ann Plast Surg., 18 (6), pp. 527-532",
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