A method for obtaining localized spectra from arbitrarily shaped regions of interest is described. When a sample consists of homogeneous compartments or domains, spectra localized in each compartment can be obtained from signals of single voxels with regular shapes by solving a set of simultaneous linear equations. Experimental demonstrations on a phantom and on human brain in vivo for a two compartment, two voxel case are presented. The issue of signal-to-noise ratio is also discussed.
- Arbitrary shape
- Magnetic resonance spectroscopy
ASJC Scopus subject areas
- Clinical Biochemistry
- Structural Biology
- Radiology Nuclear Medicine and imaging
- Condensed Matter Physics