Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet

Jiun-Rong Chen, Shih Ming Liu, Suh-Ching Yang, Kunio Suetsuna

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.

Original languageEnglish
Pages (from-to)929-933
Number of pages5
JournalNutrition
Volume20
Issue number10
DOIs
Publication statusPublished - Oct 2004

Fingerprint

Sprague Dawley Rats
Cholesterol
Diet
Lipids
Liver
Control Groups
Lipid Metabolism
Feces
Powders
LDL Cholesterol
Weight Gain
Triglycerides
Eating
Body Weight

Keywords

  • cholesterol
  • lipid metabolism
  • rat
  • soybean
  • soymilk

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Surgery
  • Medicine (miscellaneous)

Cite this

Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet. / Chen, Jiun-Rong; Liu, Shih Ming; Yang, Suh-Ching; Suetsuna, Kunio.

In: Nutrition, Vol. 20, No. 10, 10.2004, p. 929-933.

Research output: Contribution to journalArticle

@article{4768ff67a69e4b49b286f19008ae1199,
title = "Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet",
abstract = "Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3{\%}) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15{\%} soymilk powder in the diet), and S2 (22.5{\%}). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.",
keywords = "cholesterol, lipid metabolism, rat, soybean, soymilk",
author = "Jiun-Rong Chen and Liu, {Shih Ming} and Suh-Ching Yang and Kunio Suetsuna",
year = "2004",
month = "10",
doi = "10.1016/j.nut.2004.06.015",
language = "English",
volume = "20",
pages = "929--933",
journal = "Nutrition",
issn = "0899-9007",
publisher = "Elsevier Inc.",
number = "10",

}

TY - JOUR

T1 - Soymilk intake is associated with plasma and liver lipid profiles in rats fed a high-cholesterol diet

AU - Chen, Jiun-Rong

AU - Liu, Shih Ming

AU - Yang, Suh-Ching

AU - Suetsuna, Kunio

PY - 2004/10

Y1 - 2004/10

N2 - Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.

AB - Objective This study investigated the effects of soymilk on lipid metabolism in Sprague-Dawley rats fed a cholesterol-enriched (0.3%) diet. Methods Thirty male Sprague-Dawley rats weighing 230.0 ± 9.8 g were randomly assigned to one of three groups: control, S1 (containing 15% soymilk powder in the diet), and S2 (22.5%). After 8 wk, lipid profiles of the plasma, liver, and feces were determined. Results Body weight gain, daily food intake, and feeding efficiency showed no differences across groups (P > 0.05). The experimental groups had significantly lower plasma levels of cholesterol, triacylglycerol, and low-density lipoprotein cholesterol than the control group (P <0.05) at weeks 4 and 8. However, total fecal excretion of neutral steroid did not significantly differ across groups (P > 0.05). Conclusion Soymilk affects the metabolism of plasma cholesterol in Sprague-Dawley rats.

KW - cholesterol

KW - lipid metabolism

KW - rat

KW - soybean

KW - soymilk

UR - http://www.scopus.com/inward/record.url?scp=4944227131&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4944227131&partnerID=8YFLogxK

U2 - 10.1016/j.nut.2004.06.015

DO - 10.1016/j.nut.2004.06.015

M3 - Article

VL - 20

SP - 929

EP - 933

JO - Nutrition

JF - Nutrition

SN - 0899-9007

IS - 10

ER -