Sonographic Features Predictive of Benign Thyroid Nodules

Important of Avoiding Unnecessary Ultrasound-Guided Fine Needle Aspiration Biopsy

Research output: Contribution to conferencePaper

Abstract

PURPOSE: We aimed to develop a feature-oriented approach to characterize benign thyroid nodules that do not require ultrasound-guided fine needle aspiration (US-guided FNA). MATERIALS AND METHODS: We finally reviewed 374 patients (298 women and 76 men) having complete medical records and US-guided FNA. The nodular content (solid or cystic); echogenicity (hyperechoic, isoechoic, hypoechoic) relative to strap muscle; calcification (micro, coarse, or absent); nodular margin (well-defined or ill-defined); vascularity (increased or decreased) relative to the normal part of the thyroid tissue; and lymphadenopathy (neck node with calcification or short-axis > 10 mm) were evaluated. Finally, all US features were classified into 3 category: 1). Benign nodules that did not require US-guided FNA but follow-up 6 months to 12 months later was required; 2). Indeterminate, which can be follow-up 6 months later or US-guided FNA; 3).Atypical nodules or suspected carcinoma, which required US-guided FNA. RESULTS: Of the 374 nodules, 354 (95%) were benign and 20 (5%) malignant. There were 260 thyroid nodules (69.5%) that proved benign on cytology. The following US features were classified as category 1: without calcification, well-defined margins, without increase vascularity and no lymphadenopathy. There were 60 thyroid nodules (16%) classified as category 2. Indeterminate. The remaining 54 thyroid nodules (14.4%) with US features of calcification, blurred margins, increase vascularity, lymphadenopathy were classified as category 3. CONCLUSION: The US features of no calcification, no increased vascularity, well-defined margin, and no lymph node enlargement are highly predictive of benign nodules, and thereby, aspiration biopsy can be avoided in clinical practice.
Original languageEnglish
Publication statusPublished - Mar 2012
EventTHE 61ST ANNUAL MEETING OF THE RSROC - NTUH International Convention Center, Taipei, Taiwan
Duration: Mar 24 2014Mar 25 2014
https://www.rsroc.org.tw/annual/annualnews_detail.asp?id=42

Conference

ConferenceTHE 61ST ANNUAL MEETING OF THE RSROC
CountryTaiwan
CityTaipei
Period3/24/143/25/14
Internet address

Fingerprint

Thyroid Nodule
Fine Needle Biopsy
Needle Biopsy
Lymph
Cell Biology
Thyroid Gland
Neck
Carcinoma
Muscles

Cite this

Sonographic Features Predictive of Benign Thyroid Nodules : Important of Avoiding Unnecessary Ultrasound-Guided Fine Needle Aspiration Biopsy. / Tay, SheeYen; Chen, Chia-Yuen; Chan, Wing P.

2012. Paper presented at THE 61ST ANNUAL MEETING OF THE RSROC , Taipei, Taiwan.

Research output: Contribution to conferencePaper

@conference{11c407c57a914883ad92eff6345482a9,
title = "Sonographic Features Predictive of Benign Thyroid Nodules: Important of Avoiding Unnecessary Ultrasound-Guided Fine Needle Aspiration Biopsy",
abstract = "PURPOSE: We aimed to develop a feature-oriented approach to characterize benign thyroid nodules that do not require ultrasound-guided fine needle aspiration (US-guided FNA). MATERIALS AND METHODS: We finally reviewed 374 patients (298 women and 76 men) having complete medical records and US-guided FNA. The nodular content (solid or cystic); echogenicity (hyperechoic, isoechoic, hypoechoic) relative to strap muscle; calcification (micro, coarse, or absent); nodular margin (well-defined or ill-defined); vascularity (increased or decreased) relative to the normal part of the thyroid tissue; and lymphadenopathy (neck node with calcification or short-axis > 10 mm) were evaluated. Finally, all US features were classified into 3 category: 1). Benign nodules that did not require US-guided FNA but follow-up 6 months to 12 months later was required; 2). Indeterminate, which can be follow-up 6 months later or US-guided FNA; 3).Atypical nodules or suspected carcinoma, which required US-guided FNA. RESULTS: Of the 374 nodules, 354 (95{\%}) were benign and 20 (5{\%}) malignant. There were 260 thyroid nodules (69.5{\%}) that proved benign on cytology. The following US features were classified as category 1: without calcification, well-defined margins, without increase vascularity and no lymphadenopathy. There were 60 thyroid nodules (16{\%}) classified as category 2. Indeterminate. The remaining 54 thyroid nodules (14.4{\%}) with US features of calcification, blurred margins, increase vascularity, lymphadenopathy were classified as category 3. CONCLUSION: The US features of no calcification, no increased vascularity, well-defined margin, and no lymph node enlargement are highly predictive of benign nodules, and thereby, aspiration biopsy can be avoided in clinical practice.",
author = "SheeYen Tay and Chia-Yuen Chen and Chan, {Wing P.}",
year = "2012",
month = "3",
language = "English",
note = "THE 61ST ANNUAL MEETING OF THE RSROC ; Conference date: 24-03-2014 Through 25-03-2014",
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AU - Chan, Wing P.

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N2 - PURPOSE: We aimed to develop a feature-oriented approach to characterize benign thyroid nodules that do not require ultrasound-guided fine needle aspiration (US-guided FNA). MATERIALS AND METHODS: We finally reviewed 374 patients (298 women and 76 men) having complete medical records and US-guided FNA. The nodular content (solid or cystic); echogenicity (hyperechoic, isoechoic, hypoechoic) relative to strap muscle; calcification (micro, coarse, or absent); nodular margin (well-defined or ill-defined); vascularity (increased or decreased) relative to the normal part of the thyroid tissue; and lymphadenopathy (neck node with calcification or short-axis > 10 mm) were evaluated. Finally, all US features were classified into 3 category: 1). Benign nodules that did not require US-guided FNA but follow-up 6 months to 12 months later was required; 2). Indeterminate, which can be follow-up 6 months later or US-guided FNA; 3).Atypical nodules or suspected carcinoma, which required US-guided FNA. RESULTS: Of the 374 nodules, 354 (95%) were benign and 20 (5%) malignant. There were 260 thyroid nodules (69.5%) that proved benign on cytology. The following US features were classified as category 1: without calcification, well-defined margins, without increase vascularity and no lymphadenopathy. There were 60 thyroid nodules (16%) classified as category 2. Indeterminate. The remaining 54 thyroid nodules (14.4%) with US features of calcification, blurred margins, increase vascularity, lymphadenopathy were classified as category 3. CONCLUSION: The US features of no calcification, no increased vascularity, well-defined margin, and no lymph node enlargement are highly predictive of benign nodules, and thereby, aspiration biopsy can be avoided in clinical practice.

AB - PURPOSE: We aimed to develop a feature-oriented approach to characterize benign thyroid nodules that do not require ultrasound-guided fine needle aspiration (US-guided FNA). MATERIALS AND METHODS: We finally reviewed 374 patients (298 women and 76 men) having complete medical records and US-guided FNA. The nodular content (solid or cystic); echogenicity (hyperechoic, isoechoic, hypoechoic) relative to strap muscle; calcification (micro, coarse, or absent); nodular margin (well-defined or ill-defined); vascularity (increased or decreased) relative to the normal part of the thyroid tissue; and lymphadenopathy (neck node with calcification or short-axis > 10 mm) were evaluated. Finally, all US features were classified into 3 category: 1). Benign nodules that did not require US-guided FNA but follow-up 6 months to 12 months later was required; 2). Indeterminate, which can be follow-up 6 months later or US-guided FNA; 3).Atypical nodules or suspected carcinoma, which required US-guided FNA. RESULTS: Of the 374 nodules, 354 (95%) were benign and 20 (5%) malignant. There were 260 thyroid nodules (69.5%) that proved benign on cytology. The following US features were classified as category 1: without calcification, well-defined margins, without increase vascularity and no lymphadenopathy. There were 60 thyroid nodules (16%) classified as category 2. Indeterminate. The remaining 54 thyroid nodules (14.4%) with US features of calcification, blurred margins, increase vascularity, lymphadenopathy were classified as category 3. CONCLUSION: The US features of no calcification, no increased vascularity, well-defined margin, and no lymph node enlargement are highly predictive of benign nodules, and thereby, aspiration biopsy can be avoided in clinical practice.

M3 - Paper

ER -