Sonographic Evaluation of Lower-limbs Entheses in Subclinical Patients Undergoing Hemodialysis

林 正輝(Cheng-Hui Lin), 項 正川(Jeng-Chuan Shiang), 蔡 明凱(Ming-Kai Tsai), 張 棋楨(Chi-Ching Chang), 張 德明(Deh-Ming Chang)

Research output: Contribution to journalArticle

Abstract

Objective: To survey the prevalence of entheseal abnormality in the lower limbs in subclinical patients undergoing hemodialysis by musculoskeletal ultrasound (MSUS), rate the severity of abnormalities using the Glasgow Ultrasound Enthesitis Scoring system (GUESS), and correlate the score with other clinical factors.Methods: Forty-eight subclinical patients who had undergone hemodialysis for at least 4 months were divided into 2 groups. The groups were compared for the total GUESS score, thickness score, erosion score, enthesophyte score, and bursitis score. We then assessed the correlations between these scores and the duration of dialysis, sex, age, body mass index (BMI), and levels of serum biomarkers.Results: The duration of hemodialysis was found to be significantly correlated with the total GUESS score (p<0.001, r = 0.88) and enthesophyte score (p<0.001, r = 0.71). No significant correlation was detected between the scores and the following variables: age; sex; BMI; calcium-phosphorus product; and serum levels of calcium, phosphorous, parathormone, uric acid, triglycerides, cholesterol, and C-reactive protein. The prevalence of bilateral lower limb enthesopathy, determined on the basis of grayscale musculoskeletal ultrasound examination, was 21.8%.Conclusion: Hemodialysis patients may develop lower limb enthesopathy, which worsens with increase in the duration of hemodialysis, even in the absence of obvious clinical symptoms or signs. MSUS should be more widely employed by clinicians for the early diagnosis of enthesopathy in subclinical hemodialysis patients.
Original languageEnglish
Pages (from-to)41-48
Number of pages8
JournalFormosan Journal of Rheumatology
Volume26
Issue number1&2
Publication statusPublished - 2012

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Renal Dialysis
Lower Extremity
Body Mass Index
Calcium
Bursitis
Uric Acid
Parathyroid Hormone
Serum
C-Reactive Protein
Phosphorus
Signs and Symptoms
Early Diagnosis
Dialysis
Triglycerides
Biomarkers
Cholesterol
Enthesopathy

Keywords

  • 血液透析
  • 接骨點病變
  • Musculoskeletal ultrasound
  • enthesopathy
  • hemodialysis

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林正輝(Cheng-Hui L, 項正川(Jeng-Chuan S, 蔡明凱(Ming-Kai T, 張棋楨(Chi-Ching C, & 張德明(Deh-Ming C (2012). Sonographic Evaluation of Lower-limbs Entheses in Subclinical Patients Undergoing Hemodialysis. Formosan Journal of Rheumatology, 26(1&2), 41-48.

Sonographic Evaluation of Lower-limbs Entheses in Subclinical Patients Undergoing Hemodialysis. / 林正輝(Cheng-Hui Lin); 項正川(Jeng-Chuan Shiang); 蔡明凱(Ming-Kai Tsai); 張棋楨(Chi-Ching Chang); 張德明(Deh-Ming Chang).

In: Formosan Journal of Rheumatology, Vol. 26, No. 1&2, 2012, p. 41-48.

Research output: Contribution to journalArticle

林正輝(Cheng-HuiL, 項正川(Jeng-ChuanS, 蔡明凱(Ming-KaiT, 張棋楨(Chi-ChingC & 張德明(Deh-MingC 2012, 'Sonographic Evaluation of Lower-limbs Entheses in Subclinical Patients Undergoing Hemodialysis', Formosan Journal of Rheumatology, vol. 26, no. 1&2, pp. 41-48.
林正輝(Cheng-HuiL, 項正川(Jeng-ChuanS, 蔡明凱(Ming-KaiT, 張棋楨(Chi-ChingC, 張德明(Deh-MingC. Sonographic Evaluation of Lower-limbs Entheses in Subclinical Patients Undergoing Hemodialysis. Formosan Journal of Rheumatology. 2012;26(1&2):41-48.
林正輝(Cheng-Hui Lin) ; 項正川(Jeng-Chuan Shiang) ; 蔡明凱(Ming-Kai Tsai) ; 張棋楨(Chi-Ching Chang) ; 張德明(Deh-Ming Chang). / Sonographic Evaluation of Lower-limbs Entheses in Subclinical Patients Undergoing Hemodialysis. In: Formosan Journal of Rheumatology. 2012 ; Vol. 26, No. 1&2. pp. 41-48.
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abstract = "Objective: To survey the prevalence of entheseal abnormality in the lower limbs in subclinical patients undergoing hemodialysis by musculoskeletal ultrasound (MSUS), rate the severity of abnormalities using the Glasgow Ultrasound Enthesitis Scoring system (GUESS), and correlate the score with other clinical factors.Methods: Forty-eight subclinical patients who had undergone hemodialysis for at least 4 months were divided into 2 groups. The groups were compared for the total GUESS score, thickness score, erosion score, enthesophyte score, and bursitis score. We then assessed the correlations between these scores and the duration of dialysis, sex, age, body mass index (BMI), and levels of serum biomarkers.Results: The duration of hemodialysis was found to be significantly correlated with the total GUESS score (p<0.001, r = 0.88) and enthesophyte score (p<0.001, r = 0.71). No significant correlation was detected between the scores and the following variables: age; sex; BMI; calcium-phosphorus product; and serum levels of calcium, phosphorous, parathormone, uric acid, triglycerides, cholesterol, and C-reactive protein. The prevalence of bilateral lower limb enthesopathy, determined on the basis of grayscale musculoskeletal ultrasound examination, was 21.8{\%}.Conclusion: Hemodialysis patients may develop lower limb enthesopathy, which worsens with increase in the duration of hemodialysis, even in the absence of obvious clinical symptoms or signs. MSUS should be more widely employed by clinicians for the early diagnosis of enthesopathy in subclinical hemodialysis patients.",
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T1 - Sonographic Evaluation of Lower-limbs Entheses in Subclinical Patients Undergoing Hemodialysis

AU - 林, 正輝(Cheng-Hui Lin)

AU - 項, 正川(Jeng-Chuan Shiang)

AU - 蔡, 明凱(Ming-Kai Tsai)

AU - 張, 棋楨(Chi-Ching Chang)

AU - 張, 德明(Deh-Ming Chang)

PY - 2012

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N2 - Objective: To survey the prevalence of entheseal abnormality in the lower limbs in subclinical patients undergoing hemodialysis by musculoskeletal ultrasound (MSUS), rate the severity of abnormalities using the Glasgow Ultrasound Enthesitis Scoring system (GUESS), and correlate the score with other clinical factors.Methods: Forty-eight subclinical patients who had undergone hemodialysis for at least 4 months were divided into 2 groups. The groups were compared for the total GUESS score, thickness score, erosion score, enthesophyte score, and bursitis score. We then assessed the correlations between these scores and the duration of dialysis, sex, age, body mass index (BMI), and levels of serum biomarkers.Results: The duration of hemodialysis was found to be significantly correlated with the total GUESS score (p<0.001, r = 0.88) and enthesophyte score (p<0.001, r = 0.71). No significant correlation was detected between the scores and the following variables: age; sex; BMI; calcium-phosphorus product; and serum levels of calcium, phosphorous, parathormone, uric acid, triglycerides, cholesterol, and C-reactive protein. The prevalence of bilateral lower limb enthesopathy, determined on the basis of grayscale musculoskeletal ultrasound examination, was 21.8%.Conclusion: Hemodialysis patients may develop lower limb enthesopathy, which worsens with increase in the duration of hemodialysis, even in the absence of obvious clinical symptoms or signs. MSUS should be more widely employed by clinicians for the early diagnosis of enthesopathy in subclinical hemodialysis patients.

AB - Objective: To survey the prevalence of entheseal abnormality in the lower limbs in subclinical patients undergoing hemodialysis by musculoskeletal ultrasound (MSUS), rate the severity of abnormalities using the Glasgow Ultrasound Enthesitis Scoring system (GUESS), and correlate the score with other clinical factors.Methods: Forty-eight subclinical patients who had undergone hemodialysis for at least 4 months were divided into 2 groups. The groups were compared for the total GUESS score, thickness score, erosion score, enthesophyte score, and bursitis score. We then assessed the correlations between these scores and the duration of dialysis, sex, age, body mass index (BMI), and levels of serum biomarkers.Results: The duration of hemodialysis was found to be significantly correlated with the total GUESS score (p<0.001, r = 0.88) and enthesophyte score (p<0.001, r = 0.71). No significant correlation was detected between the scores and the following variables: age; sex; BMI; calcium-phosphorus product; and serum levels of calcium, phosphorous, parathormone, uric acid, triglycerides, cholesterol, and C-reactive protein. The prevalence of bilateral lower limb enthesopathy, determined on the basis of grayscale musculoskeletal ultrasound examination, was 21.8%.Conclusion: Hemodialysis patients may develop lower limb enthesopathy, which worsens with increase in the duration of hemodialysis, even in the absence of obvious clinical symptoms or signs. MSUS should be more widely employed by clinicians for the early diagnosis of enthesopathy in subclinical hemodialysis patients.

KW - 血液透析

KW - 接骨點病變

KW - Musculoskeletal ultrasound

KW - enthesopathy

KW - hemodialysis

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VL - 26

SP - 41

EP - 48

JO - Formosan Journal of Rheumatology

JF - Formosan Journal of Rheumatology

SN - 2075-0374

IS - 1&2

ER -