Solitary pleural plasmacytomas manifested as a massive pleural effusion without evidence of monoclonal gammopathy

Po Hao Feng, Chung Chi Huang, Chih Wei Wang, Yao Kuang Wu, Ying Huang Tsai

Research output: Contribution to journalArticle

7 Citations (Scopus)


The majority of extramedullary plasmacytomas involve the upper respiratory tract but only a few are associated with serum monoclonal gammopathy. Most extramedullary plasmacytomas respond to local radiotherapy and have a better prognosis than multiple myeloma. Solitary plasmacytomas, involving the pleura, are very rare. This case report describes a patient with a solitary extramedullary plasmacytoma involving the pleura, and no evidence of serum, urine or pleural fluid paraproteins. Diagnosis was made by strongly positive immunohistochemical stains with CD38, CD138 and MUM-1 of the pleural tumour. The response to both radiotherapy and chemotherapy was poor and the patient died shortly after diagnosis.

Original languageEnglish
Pages (from-to)751-753
Number of pages3
Issue number5
Publication statusPublished - Jul 2008
Externally publishedYes



  • Multiple myeloma
  • Plasma cell tumour
  • Plasmacytoma
  • Pleural monoclonal gammopathy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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