Sodium trimethylsilanethiolate in novel cyclizations for synthesis of aromatic heterotricyclic compounds

Long Li Lai, Pen Yuan Lin, Wen Hong Huang, Min Jen Shiao, Jih Ru Hwu

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A new method was developed for synthesis of aromatic heterotricyclic compounds in 50-64% yields from diaryls bearing a functionality including OMe, COOMe, and CN, and a leaving group (i.e., F and OMe) by use of Me3SiSNa in 1,3-dimethyl-2-imidazolidinone at 120-150 °C.

Original languageEnglish
Pages (from-to)3545-3546
Number of pages2
JournalTetrahedron Letters
Volume35
Issue number21
DOIs
Publication statusPublished - May 23 1994
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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