Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy

Yu-Ching Wen; Wei Yu Chen; Wei Jiunn Lee; Shun Fa Yang; Liang Ming Lee; Ming Hsien Chien

doi:10.1016/j.cca.2014.01.036

Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy

Yu-Ching Wen, Wei Yu Chen, Wei Jiunn Lee, Shun Fa Yang, Liang Ming Lee, Ming Hsien Chien

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Background: We retrospectively investigated the relationship between immunohistochemical staining of radical prostatectomy (RP) specimens for snail and cancer recurrence. Methods: Seventy-six patients with prostate cancer who underwent RP were enrolled, and 53 patients were ultimately collected whose cancer was pathologically defined as T2. We detected the expression of snail using tissue microarrays. The snail image score was determined by the intensity. ×. tumor percentage, and a high score was defined as 8 (1-12 points). Results: The snail image scores and Gleason score sums were correlated with recurrence-free survival according to a log-rank test (p

Original language	English
Pages (from-to)	169-173
Number of pages	5
Journal	Clinica Chimica Acta
Volume	431
DOIs	https://doi.org/10.1016/j.cca.2014.01.036
Publication status	Published - Apr 20 2014

Keywords

Prostate cancer
Radical prostatectomy
Recurrence
Snail
Stage T2

ASJC Scopus subject areas

Biochemistry
Clinical Biochemistry
Biochemistry, medical
Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.cca.2014.01.036

Cite this

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title = "Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy",

abstract = "Background: We retrospectively investigated the relationship between immunohistochemical staining of radical prostatectomy (RP) specimens for snail and cancer recurrence. Methods: Seventy-six patients with prostate cancer who underwent RP were enrolled, and 53 patients were ultimately collected whose cancer was pathologically defined as T2. We detected the expression of snail using tissue microarrays. The snail image score was determined by the intensity. ×. tumor percentage, and a high score was defined as 8 (1-12 points). Results: The snail image scores and Gleason score sums were correlated with recurrence-free survival according to a log-rank test (p",

keywords = "Prostate cancer, Radical prostatectomy, Recurrence, Snail, Stage T2",

author = "Yu-Ching Wen and Chen, {Wei Yu} and Lee, {Wei Jiunn} and Yang, {Shun Fa} and Lee, {Liang Ming} and Chien, {Ming Hsien}",

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doi = "10.1016/j.cca.2014.01.036",

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pages = "169--173",

journal = "Clinica Chimica Acta",

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T1 - Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy

AU - Wen, Yu-Ching

AU - Chen, Wei Yu

AU - Lee, Wei Jiunn

AU - Yang, Shun Fa

AU - Lee, Liang Ming

AU - Chien, Ming Hsien

PY - 2014/4/20

Y1 - 2014/4/20

N2 - Background: We retrospectively investigated the relationship between immunohistochemical staining of radical prostatectomy (RP) specimens for snail and cancer recurrence. Methods: Seventy-six patients with prostate cancer who underwent RP were enrolled, and 53 patients were ultimately collected whose cancer was pathologically defined as T2. We detected the expression of snail using tissue microarrays. The snail image score was determined by the intensity. ×. tumor percentage, and a high score was defined as 8 (1-12 points). Results: The snail image scores and Gleason score sums were correlated with recurrence-free survival according to a log-rank test (p

AB - Background: We retrospectively investigated the relationship between immunohistochemical staining of radical prostatectomy (RP) specimens for snail and cancer recurrence. Methods: Seventy-six patients with prostate cancer who underwent RP were enrolled, and 53 patients were ultimately collected whose cancer was pathologically defined as T2. We detected the expression of snail using tissue microarrays. The snail image score was determined by the intensity. ×. tumor percentage, and a high score was defined as 8 (1-12 points). Results: The snail image scores and Gleason score sums were correlated with recurrence-free survival according to a log-rank test (p

KW - Prostate cancer

KW - Radical prostatectomy

KW - Recurrence

KW - Snail

KW - Stage T2

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Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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