Sleep Mediates the Relationship Between Depression and Cognitive Impairment in Older Men

Chia Rung Wu, Pin Yuan Chen, Shu Hua Hsieh, Hui-Chuan Huang, Yu Ting Chen, Ting Jhen Chen, Hsiao Yean Chiu

Research output: Contribution to journalArticle

Abstract

Sleep and depression are strongly associated with cognitive impairment. The role of sleep disturbances in the adverse effect of depression on cognitive dysfunction in older adults remains unclear. This study explored the mediating effect of self-reported sleep disturbances on the relationship between depression and cognitive impairment in older adults according to sex differences. This study derived data from the 2009 Taiwan National Health Interview Survey and included 2,175 community-dwelling adults aged 65 years and older (men = 991; women = 1,184). Sleep disturbances were measured using self-reported survey questions. The Center for Epidemiological Studies Depression scale was used to assess depression. The Mini-Mental State Examination was used to evaluate cognitive impairment. A higher proportion of female older persons had cognitive impairment and depression than male older persons (cognition: 24.4% vs. 11.5%; depression: 17.0% vs. 10.8%). The meditating effect of sleep was detected in only men. Difficulty in initiating sleep was a complete mediator of the adverse effect of depression on cognitive impairment (Sobel test: p =.03). In summary, difficultly in initiating sleep may be a crucial, treatable mediator of the adverse effect of depression on cognitive impairment in older men.

Original languageEnglish
JournalAmerican Journal of Men's Health
Volume13
DOIs
Publication statusPublished - Jan 1 2019

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sleep
Sleep
Depression
Independent Living
Cognitive Dysfunction
Health Surveys
Taiwan
Sex Characteristics
Cognition
Epidemiologic Studies
cognition
Interviews
examination
interview
health

Keywords

  • cognitive impairment
  • depression
  • older people
  • sleep

ASJC Scopus subject areas

  • Health(social science)
  • Public Health, Environmental and Occupational Health

Cite this

Sleep Mediates the Relationship Between Depression and Cognitive Impairment in Older Men. / Wu, Chia Rung; Chen, Pin Yuan; Hsieh, Shu Hua; Huang, Hui-Chuan; Chen, Yu Ting; Chen, Ting Jhen; Chiu, Hsiao Yean.

In: American Journal of Men's Health, Vol. 13, 01.01.2019.

Research output: Contribution to journalArticle

Wu, Chia Rung ; Chen, Pin Yuan ; Hsieh, Shu Hua ; Huang, Hui-Chuan ; Chen, Yu Ting ; Chen, Ting Jhen ; Chiu, Hsiao Yean. / Sleep Mediates the Relationship Between Depression and Cognitive Impairment in Older Men. In: American Journal of Men's Health. 2019 ; Vol. 13.
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