Skull metastasis from hepatocellular carcinoma

Cheng T. Hsieh, J. M. Sun, W. C. Tsai, Tung Han Tsai, Yung-Hsiao Chiang, M. Y. Liu

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Metastasis to the skull frequently occurs in patients with lung, breast and prostate cancer. However, skull metastases from hepatocellular carcinoma (HCC) have been rarely reported. We review the literature on skull metastasis from HCC and report a case of a 46-year-old male, who was diagnosed as HCC and was operated on by trans-arterial embolization and lobectomy in Oct. 2004. He complained of a painless mass over the left frontal region for two months. Radiograph of the skull revealed an osteolytic mass about 4-5 cm in size over the left frontal region. A cranial computerized tomography demonstrated a destructive lesion with soft tissue mass over the left frontal region. A left frontal craniectomy was performed and tumor was totally removed. The histological diagnosis was cranial metastasis from HCC. Postoperative recovery was uneventful without any neurological deficits. Because of improved and advancing treatment for HCC, survival time for HCC has been lengthened and distant metastasese will thus be found to increase. Early diagnosis is essential to treat the primary disease. Skull metastases from HCC should be considered as a differential diagnosis in patients with scalp subcutaneous mass and osteolytic defect on X-ray skull films.

Original languageEnglish
Pages (from-to)185-190
Number of pages6
JournalActa Neurochirurgica
Volume149
Issue number2
DOIs
Publication statusPublished - Feb 2007
Externally publishedYes

Fingerprint

Skull
Hepatocellular Carcinoma
Neoplasm Metastasis
X-Ray Film
Scalp
Early Diagnosis
Lung Neoplasms
Prostatic Neoplasms
Differential Diagnosis
Tomography
Breast Neoplasms
Survival
Neoplasms

Keywords

  • Calvarium metastasis
  • Hepatocellular carcinoma
  • Hepatoma
  • Skull metastasis

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Hsieh, C. T., Sun, J. M., Tsai, W. C., Tsai, T. H., Chiang, Y-H., & Liu, M. Y. (2007). Skull metastasis from hepatocellular carcinoma. Acta Neurochirurgica, 149(2), 185-190. https://doi.org/10.1007/s00701-006-1071-3

Skull metastasis from hepatocellular carcinoma. / Hsieh, Cheng T.; Sun, J. M.; Tsai, W. C.; Tsai, Tung Han; Chiang, Yung-Hsiao; Liu, M. Y.

In: Acta Neurochirurgica, Vol. 149, No. 2, 02.2007, p. 185-190.

Research output: Contribution to journalArticle

Hsieh, CT, Sun, JM, Tsai, WC, Tsai, TH, Chiang, Y-H & Liu, MY 2007, 'Skull metastasis from hepatocellular carcinoma', Acta Neurochirurgica, vol. 149, no. 2, pp. 185-190. https://doi.org/10.1007/s00701-006-1071-3
Hsieh, Cheng T. ; Sun, J. M. ; Tsai, W. C. ; Tsai, Tung Han ; Chiang, Yung-Hsiao ; Liu, M. Y. / Skull metastasis from hepatocellular carcinoma. In: Acta Neurochirurgica. 2007 ; Vol. 149, No. 2. pp. 185-190.
@article{d300c4d7fdf84aed8b50b3850f469ce6,
title = "Skull metastasis from hepatocellular carcinoma",
abstract = "Metastasis to the skull frequently occurs in patients with lung, breast and prostate cancer. However, skull metastases from hepatocellular carcinoma (HCC) have been rarely reported. We review the literature on skull metastasis from HCC and report a case of a 46-year-old male, who was diagnosed as HCC and was operated on by trans-arterial embolization and lobectomy in Oct. 2004. He complained of a painless mass over the left frontal region for two months. Radiograph of the skull revealed an osteolytic mass about 4-5 cm in size over the left frontal region. A cranial computerized tomography demonstrated a destructive lesion with soft tissue mass over the left frontal region. A left frontal craniectomy was performed and tumor was totally removed. The histological diagnosis was cranial metastasis from HCC. Postoperative recovery was uneventful without any neurological deficits. Because of improved and advancing treatment for HCC, survival time for HCC has been lengthened and distant metastasese will thus be found to increase. Early diagnosis is essential to treat the primary disease. Skull metastases from HCC should be considered as a differential diagnosis in patients with scalp subcutaneous mass and osteolytic defect on X-ray skull films.",
keywords = "Calvarium metastasis, Hepatocellular carcinoma, Hepatoma, Skull metastasis",
author = "Hsieh, {Cheng T.} and Sun, {J. M.} and Tsai, {W. C.} and Tsai, {Tung Han} and Yung-Hsiao Chiang and Liu, {M. Y.}",
year = "2007",
month = "2",
doi = "10.1007/s00701-006-1071-3",
language = "English",
volume = "149",
pages = "185--190",
journal = "Acta Neurochirurgica",
issn = "0001-6268",
publisher = "Springer Wien",
number = "2",

}

TY - JOUR

T1 - Skull metastasis from hepatocellular carcinoma

AU - Hsieh, Cheng T.

AU - Sun, J. M.

AU - Tsai, W. C.

AU - Tsai, Tung Han

AU - Chiang, Yung-Hsiao

AU - Liu, M. Y.

PY - 2007/2

Y1 - 2007/2

N2 - Metastasis to the skull frequently occurs in patients with lung, breast and prostate cancer. However, skull metastases from hepatocellular carcinoma (HCC) have been rarely reported. We review the literature on skull metastasis from HCC and report a case of a 46-year-old male, who was diagnosed as HCC and was operated on by trans-arterial embolization and lobectomy in Oct. 2004. He complained of a painless mass over the left frontal region for two months. Radiograph of the skull revealed an osteolytic mass about 4-5 cm in size over the left frontal region. A cranial computerized tomography demonstrated a destructive lesion with soft tissue mass over the left frontal region. A left frontal craniectomy was performed and tumor was totally removed. The histological diagnosis was cranial metastasis from HCC. Postoperative recovery was uneventful without any neurological deficits. Because of improved and advancing treatment for HCC, survival time for HCC has been lengthened and distant metastasese will thus be found to increase. Early diagnosis is essential to treat the primary disease. Skull metastases from HCC should be considered as a differential diagnosis in patients with scalp subcutaneous mass and osteolytic defect on X-ray skull films.

AB - Metastasis to the skull frequently occurs in patients with lung, breast and prostate cancer. However, skull metastases from hepatocellular carcinoma (HCC) have been rarely reported. We review the literature on skull metastasis from HCC and report a case of a 46-year-old male, who was diagnosed as HCC and was operated on by trans-arterial embolization and lobectomy in Oct. 2004. He complained of a painless mass over the left frontal region for two months. Radiograph of the skull revealed an osteolytic mass about 4-5 cm in size over the left frontal region. A cranial computerized tomography demonstrated a destructive lesion with soft tissue mass over the left frontal region. A left frontal craniectomy was performed and tumor was totally removed. The histological diagnosis was cranial metastasis from HCC. Postoperative recovery was uneventful without any neurological deficits. Because of improved and advancing treatment for HCC, survival time for HCC has been lengthened and distant metastasese will thus be found to increase. Early diagnosis is essential to treat the primary disease. Skull metastases from HCC should be considered as a differential diagnosis in patients with scalp subcutaneous mass and osteolytic defect on X-ray skull films.

KW - Calvarium metastasis

KW - Hepatocellular carcinoma

KW - Hepatoma

KW - Skull metastasis

UR - http://www.scopus.com/inward/record.url?scp=33846811208&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846811208&partnerID=8YFLogxK

U2 - 10.1007/s00701-006-1071-3

DO - 10.1007/s00701-006-1071-3

M3 - Article

VL - 149

SP - 185

EP - 190

JO - Acta Neurochirurgica

JF - Acta Neurochirurgica

SN - 0001-6268

IS - 2

ER -