Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature

Tsung Wei Liu, Shih Han Hung, Po Yueh Chen

Research output: Contribution to journalArticle


Spindle cell carcinoma (SpCC) is a rare variant of squamous cell carcinoma (SCC). SpCC of sinonasal origin is relatively rare and more aggressive than normal SCC. It most commonly involves the maxillary sinus, and rarely the sphenoid sinus. The present study reports a case of sphenoid sinus SpCC presenting with bilateral visual loss. Following endoscopic sinus decompression surgery, the patient was referred to the Oncology Department for a staging workup, and subsequently received concurrent chemoradiotherapy; however, the vision of the patient was not recovered, despite treatment. To the best of our knowledge, this is the first reported case of synchronous inverted papilloma of the sphenoid sinus and SpCC presenting with optic nerve compression.

Original languageEnglish
Pages (from-to)401-404
Number of pages4
JournalOncology Letters
Issue number1
Publication statusPublished - Jul 1 2016



  • Head and neck
  • Sinonasal
  • Spindle cell carcinoma
  • Squamous cell carcinoma

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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