Single-walled carbon nanotube coated antibacterial paper

Preparation and mechanistic study

Archana R. Deokar, Lih Yuan Lin, Chun Chao Chang, Yong Chien Ling

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Development of carbon nanotubes toward commercial antibacterial applications warrants the understanding of their interaction mechanism with bacterial cells. The antibacterial activity and mechanism of acid-functionalized single-walled carbon nanotube (AFSWCNT) coated paper was assessed for gram-positive Staphylococcus aureus and gram-negative Escherichia coli models of bacteria. Better activity towards gram-positive bacteria was observed, whereas the presence of an outer membrane makes gram-negative bacteria more resistant to cell membrane damage caused by AFSWCNTs. Based on measured cytoplasmic efflux materials of bacteria, X-ray photoelectron spectroscopy, and scanning transmission electron microscopy combined with electron energy-loss spectroscopy imaging studies, we found that the better antibacterial activity of AFSWCNTs toward gram-positive bacteria is attributed to not only direct physical contact and piercing action, but also molecular-scale interaction with surface functional groups of bacteria. The novel antibacterial mechanism of AFSWCNTs might bring a promising strategy to design new antibacterial materials against drug-resistant bacteria species.

Original languageEnglish
Pages (from-to)2639-2646
Number of pages8
JournalJournal of Materials Chemistry B
Volume1
Issue number20
DOIs
Publication statusPublished - May 28 2013

Fingerprint

Carbon Nanotubes
Single-walled carbon nanotubes (SWCN)
Bacteria
Gram-Positive Bacteria
Electron Energy-Loss Spectroscopy
Photoelectron Spectroscopy
Scanning Transmission Electron Microscopy
Gram-Negative Bacteria
Staphylococcus aureus
Cell Membrane
Piercing
Escherichia coli
Electron energy loss spectroscopy
Acids
Cell membranes
Membranes
Functional groups
Carbon nanotubes
Pharmaceutical Preparations
X ray photoelectron spectroscopy

ASJC Scopus subject areas

  • Chemistry(all)
  • Biomedical Engineering
  • Medicine(all)
  • Materials Science(all)

Cite this

Single-walled carbon nanotube coated antibacterial paper : Preparation and mechanistic study. / Deokar, Archana R.; Lin, Lih Yuan; Chang, Chun Chao; Ling, Yong Chien.

In: Journal of Materials Chemistry B, Vol. 1, No. 20, 28.05.2013, p. 2639-2646.

Research output: Contribution to journalArticle

Deokar, Archana R. ; Lin, Lih Yuan ; Chang, Chun Chao ; Ling, Yong Chien. / Single-walled carbon nanotube coated antibacterial paper : Preparation and mechanistic study. In: Journal of Materials Chemistry B. 2013 ; Vol. 1, No. 20. pp. 2639-2646.
@article{838b40b0577943a1910339bd4dd459cc,
title = "Single-walled carbon nanotube coated antibacterial paper: Preparation and mechanistic study",
abstract = "Development of carbon nanotubes toward commercial antibacterial applications warrants the understanding of their interaction mechanism with bacterial cells. The antibacterial activity and mechanism of acid-functionalized single-walled carbon nanotube (AFSWCNT) coated paper was assessed for gram-positive Staphylococcus aureus and gram-negative Escherichia coli models of bacteria. Better activity towards gram-positive bacteria was observed, whereas the presence of an outer membrane makes gram-negative bacteria more resistant to cell membrane damage caused by AFSWCNTs. Based on measured cytoplasmic efflux materials of bacteria, X-ray photoelectron spectroscopy, and scanning transmission electron microscopy combined with electron energy-loss spectroscopy imaging studies, we found that the better antibacterial activity of AFSWCNTs toward gram-positive bacteria is attributed to not only direct physical contact and piercing action, but also molecular-scale interaction with surface functional groups of bacteria. The novel antibacterial mechanism of AFSWCNTs might bring a promising strategy to design new antibacterial materials against drug-resistant bacteria species.",
author = "Deokar, {Archana R.} and Lin, {Lih Yuan} and Chang, {Chun Chao} and Ling, {Yong Chien}",
year = "2013",
month = "5",
day = "28",
doi = "10.1039/c3tb20188k",
language = "English",
volume = "1",
pages = "2639--2646",
journal = "Journal of Materials Chemistry B",
issn = "2050-7518",
publisher = "Royal Society of Chemistry",
number = "20",

}

TY - JOUR

T1 - Single-walled carbon nanotube coated antibacterial paper

T2 - Preparation and mechanistic study

AU - Deokar, Archana R.

AU - Lin, Lih Yuan

AU - Chang, Chun Chao

AU - Ling, Yong Chien

PY - 2013/5/28

Y1 - 2013/5/28

N2 - Development of carbon nanotubes toward commercial antibacterial applications warrants the understanding of their interaction mechanism with bacterial cells. The antibacterial activity and mechanism of acid-functionalized single-walled carbon nanotube (AFSWCNT) coated paper was assessed for gram-positive Staphylococcus aureus and gram-negative Escherichia coli models of bacteria. Better activity towards gram-positive bacteria was observed, whereas the presence of an outer membrane makes gram-negative bacteria more resistant to cell membrane damage caused by AFSWCNTs. Based on measured cytoplasmic efflux materials of bacteria, X-ray photoelectron spectroscopy, and scanning transmission electron microscopy combined with electron energy-loss spectroscopy imaging studies, we found that the better antibacterial activity of AFSWCNTs toward gram-positive bacteria is attributed to not only direct physical contact and piercing action, but also molecular-scale interaction with surface functional groups of bacteria. The novel antibacterial mechanism of AFSWCNTs might bring a promising strategy to design new antibacterial materials against drug-resistant bacteria species.

AB - Development of carbon nanotubes toward commercial antibacterial applications warrants the understanding of their interaction mechanism with bacterial cells. The antibacterial activity and mechanism of acid-functionalized single-walled carbon nanotube (AFSWCNT) coated paper was assessed for gram-positive Staphylococcus aureus and gram-negative Escherichia coli models of bacteria. Better activity towards gram-positive bacteria was observed, whereas the presence of an outer membrane makes gram-negative bacteria more resistant to cell membrane damage caused by AFSWCNTs. Based on measured cytoplasmic efflux materials of bacteria, X-ray photoelectron spectroscopy, and scanning transmission electron microscopy combined with electron energy-loss spectroscopy imaging studies, we found that the better antibacterial activity of AFSWCNTs toward gram-positive bacteria is attributed to not only direct physical contact and piercing action, but also molecular-scale interaction with surface functional groups of bacteria. The novel antibacterial mechanism of AFSWCNTs might bring a promising strategy to design new antibacterial materials against drug-resistant bacteria species.

UR - http://www.scopus.com/inward/record.url?scp=84877280283&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84877280283&partnerID=8YFLogxK

U2 - 10.1039/c3tb20188k

DO - 10.1039/c3tb20188k

M3 - Article

VL - 1

SP - 2639

EP - 2646

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

SN - 2050-7518

IS - 20

ER -