Single-chain antibodies for the conformation-specific blockade of activated platelet integrin αIIbβ3 designed by subtractive selection from naive human phage libraries

Meike Schwarz, Peter Röttgen, Yoshiazuku Takada, Fabrice Le Gall, Stefan Knackmuss, Nicole Bassler, Claudia Büttner, Melvyn Little, Christoph Bode, Karlheinz Peter

Research output: Contribution to journalArticle

62 Citations (Scopus)
Original languageEnglish
Pages (from-to)1704-1706
Number of pages3
JournalFASEB Journal
Volume18
Issue number14
DOIs
Publication statusPublished - Nov 2004
Externally publishedYes

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Cricetinae
Cricetulus
immunoglobulin light chains
peptide libraries
Immunoglobulin Variable Region
Antibody Binding Sites
Immunoglobulin Light Chains
platelet activation
protein conformation
Peptide Library
Single-Chain Antibodies
Protein Conformation
Platelet Glycoprotein GPIIb-IIIa Complex
Bacteriophages
Antibody Affinity
CHO Cells
DNA libraries
Platelet Activation
integrins
fibrinogen

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology

Cite this

Single-chain antibodies for the conformation-specific blockade of activated platelet integrin αIIbβ3 designed by subtractive selection from naive human phage libraries. / Schwarz, Meike; Röttgen, Peter; Takada, Yoshiazuku; Le Gall, Fabrice; Knackmuss, Stefan; Bassler, Nicole; Büttner, Claudia; Little, Melvyn; Bode, Christoph; Peter, Karlheinz.

In: FASEB Journal, Vol. 18, No. 14, 11.2004, p. 1704-1706.

Research output: Contribution to journalArticle

Schwarz, M, Röttgen, P, Takada, Y, Le Gall, F, Knackmuss, S, Bassler, N, Büttner, C, Little, M, Bode, C & Peter, K 2004, 'Single-chain antibodies for the conformation-specific blockade of activated platelet integrin αIIbβ3 designed by subtractive selection from naive human phage libraries', FASEB Journal, vol. 18, no. 14, pp. 1704-1706. https://doi.org/10.1096/fj.04-1513fje
Schwarz, Meike ; Röttgen, Peter ; Takada, Yoshiazuku ; Le Gall, Fabrice ; Knackmuss, Stefan ; Bassler, Nicole ; Büttner, Claudia ; Little, Melvyn ; Bode, Christoph ; Peter, Karlheinz. / Single-chain antibodies for the conformation-specific blockade of activated platelet integrin αIIbβ3 designed by subtractive selection from naive human phage libraries. In: FASEB Journal. 2004 ; Vol. 18, No. 14. pp. 1704-1706.
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