Single and multiple pyogenic liver abscesses: Clinical course, etiology, and results of treatment

Fong Fu Chou, Shyr Ming Sheen-Chen, Yaw Sen Chen, Mao Chan Chen

Research output: Contribution to journalArticle

120 Citations (Scopus)

Abstract

A total of 483 patients with pyogenic liver abscess during the years 1986 to June 1995 were studied at Chang Gung Memorial Hospital in Kaohsiung: 343 were a single abscess and 140 were multiple abscesses. Males were predominantly affected by this disease. Abdominal pain was more frequent with the single abscess than with multiple abscesses, and jaundice was more frequent with multiple abscesses. Blood levels of alkaline phosphatase, bilirubin, and creatinine and the while blood cell count were significantly higher in patients with multiple abscesses than in those with a single abscess; and the hemoglobin level was higher with single abscesses. The single abscess was usually larger than 5 cm, and the multiple abscesses were usually smaller than 5 cm. The single abscess was always located on the right side (72%) and the multiple abscesses always on the right or both sides. Single abscesses mainly had a cryptogenic origin (58.9%) and multiple abscesses a biliary origin (45.0%). Liver aspirates revealed Klebsiella pneumoniae, Escherichia coli, Streptococcus, Bacteroides, Enterococcus, among others. K. pneumoniae was more often found in a single abscess and E. coli more often in multiple abscesses. Percutaneous catheter drainage and aspiration comprised the main treatment initially, and the failure rate with multiple abscesses was higher than that with single abscesses. Surgical intervention should be considered for multiple abscesses because of the underlying disease. The overall mortality with multiple abscesses (22.1%) was higher than that with a single abscess (12.8%). Partial hepatectomy produced a low mortality rate for both single and multiple abscesses and should be considered in the presence of severe hepatic destruction by an abscess or a stone.

Original languageEnglish
Pages (from-to)384-389
Number of pages6
JournalWorld Journal of Surgery
Volume21
Issue number4
DOIs
Publication statusPublished - Jan 1 1997

Fingerprint

Pyogenic Liver Abscess
Abscess
Therapeutics
Klebsiella pneumoniae

ASJC Scopus subject areas

  • Surgery

Cite this

Single and multiple pyogenic liver abscesses : Clinical course, etiology, and results of treatment. / Chou, Fong Fu; Sheen-Chen, Shyr Ming; Chen, Yaw Sen; Chen, Mao Chan.

In: World Journal of Surgery, Vol. 21, No. 4, 01.01.1997, p. 384-389.

Research output: Contribution to journalArticle

@article{f9ea90e704ee43b497520444bc1e1f49,
title = "Single and multiple pyogenic liver abscesses: Clinical course, etiology, and results of treatment",
abstract = "A total of 483 patients with pyogenic liver abscess during the years 1986 to June 1995 were studied at Chang Gung Memorial Hospital in Kaohsiung: 343 were a single abscess and 140 were multiple abscesses. Males were predominantly affected by this disease. Abdominal pain was more frequent with the single abscess than with multiple abscesses, and jaundice was more frequent with multiple abscesses. Blood levels of alkaline phosphatase, bilirubin, and creatinine and the while blood cell count were significantly higher in patients with multiple abscesses than in those with a single abscess; and the hemoglobin level was higher with single abscesses. The single abscess was usually larger than 5 cm, and the multiple abscesses were usually smaller than 5 cm. The single abscess was always located on the right side (72{\%}) and the multiple abscesses always on the right or both sides. Single abscesses mainly had a cryptogenic origin (58.9{\%}) and multiple abscesses a biliary origin (45.0{\%}). Liver aspirates revealed Klebsiella pneumoniae, Escherichia coli, Streptococcus, Bacteroides, Enterococcus, among others. K. pneumoniae was more often found in a single abscess and E. coli more often in multiple abscesses. Percutaneous catheter drainage and aspiration comprised the main treatment initially, and the failure rate with multiple abscesses was higher than that with single abscesses. Surgical intervention should be considered for multiple abscesses because of the underlying disease. The overall mortality with multiple abscesses (22.1{\%}) was higher than that with a single abscess (12.8{\%}). Partial hepatectomy produced a low mortality rate for both single and multiple abscesses and should be considered in the presence of severe hepatic destruction by an abscess or a stone.",
author = "Chou, {Fong Fu} and Sheen-Chen, {Shyr Ming} and Chen, {Yaw Sen} and Chen, {Mao Chan}",
year = "1997",
month = "1",
day = "1",
doi = "10.1007/PL00012258",
language = "English",
volume = "21",
pages = "384--389",
journal = "World Journal of Surgery",
issn = "0364-2313",
publisher = "Springer New York LLC",
number = "4",

}

TY - JOUR

T1 - Single and multiple pyogenic liver abscesses

T2 - Clinical course, etiology, and results of treatment

AU - Chou, Fong Fu

AU - Sheen-Chen, Shyr Ming

AU - Chen, Yaw Sen

AU - Chen, Mao Chan

PY - 1997/1/1

Y1 - 1997/1/1

N2 - A total of 483 patients with pyogenic liver abscess during the years 1986 to June 1995 were studied at Chang Gung Memorial Hospital in Kaohsiung: 343 were a single abscess and 140 were multiple abscesses. Males were predominantly affected by this disease. Abdominal pain was more frequent with the single abscess than with multiple abscesses, and jaundice was more frequent with multiple abscesses. Blood levels of alkaline phosphatase, bilirubin, and creatinine and the while blood cell count were significantly higher in patients with multiple abscesses than in those with a single abscess; and the hemoglobin level was higher with single abscesses. The single abscess was usually larger than 5 cm, and the multiple abscesses were usually smaller than 5 cm. The single abscess was always located on the right side (72%) and the multiple abscesses always on the right or both sides. Single abscesses mainly had a cryptogenic origin (58.9%) and multiple abscesses a biliary origin (45.0%). Liver aspirates revealed Klebsiella pneumoniae, Escherichia coli, Streptococcus, Bacteroides, Enterococcus, among others. K. pneumoniae was more often found in a single abscess and E. coli more often in multiple abscesses. Percutaneous catheter drainage and aspiration comprised the main treatment initially, and the failure rate with multiple abscesses was higher than that with single abscesses. Surgical intervention should be considered for multiple abscesses because of the underlying disease. The overall mortality with multiple abscesses (22.1%) was higher than that with a single abscess (12.8%). Partial hepatectomy produced a low mortality rate for both single and multiple abscesses and should be considered in the presence of severe hepatic destruction by an abscess or a stone.

AB - A total of 483 patients with pyogenic liver abscess during the years 1986 to June 1995 were studied at Chang Gung Memorial Hospital in Kaohsiung: 343 were a single abscess and 140 were multiple abscesses. Males were predominantly affected by this disease. Abdominal pain was more frequent with the single abscess than with multiple abscesses, and jaundice was more frequent with multiple abscesses. Blood levels of alkaline phosphatase, bilirubin, and creatinine and the while blood cell count were significantly higher in patients with multiple abscesses than in those with a single abscess; and the hemoglobin level was higher with single abscesses. The single abscess was usually larger than 5 cm, and the multiple abscesses were usually smaller than 5 cm. The single abscess was always located on the right side (72%) and the multiple abscesses always on the right or both sides. Single abscesses mainly had a cryptogenic origin (58.9%) and multiple abscesses a biliary origin (45.0%). Liver aspirates revealed Klebsiella pneumoniae, Escherichia coli, Streptococcus, Bacteroides, Enterococcus, among others. K. pneumoniae was more often found in a single abscess and E. coli more often in multiple abscesses. Percutaneous catheter drainage and aspiration comprised the main treatment initially, and the failure rate with multiple abscesses was higher than that with single abscesses. Surgical intervention should be considered for multiple abscesses because of the underlying disease. The overall mortality with multiple abscesses (22.1%) was higher than that with a single abscess (12.8%). Partial hepatectomy produced a low mortality rate for both single and multiple abscesses and should be considered in the presence of severe hepatic destruction by an abscess or a stone.

UR - http://www.scopus.com/inward/record.url?scp=0030887903&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030887903&partnerID=8YFLogxK

U2 - 10.1007/PL00012258

DO - 10.1007/PL00012258

M3 - Article

C2 - 9143569

AN - SCOPUS:0030887903

VL - 21

SP - 384

EP - 389

JO - World Journal of Surgery

JF - World Journal of Surgery

SN - 0364-2313

IS - 4

ER -