Significance of coronary artery disease and left ventricular afterload in unoperated asymptomatic aortic stenosis

Kentaro Shibayama, Masao Daimon, Hiroyuki Watanabe, Takayuki Kawata, Sakiko Miyazaki, Ryoko Morimoto-Ichikawa, Masaki Maruyama, Shuo Ju Chiang, Katsumi Miyauchi, Hiroyuki Daida

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Because the covariates of cardiovascular events in unoperated patients with asymptomatic aortic stenosis (AS) have not been adequately evaluated, we aimed to identify them. Methods and Results: A total of 230 patients with asymptomatic severe AS were retrospectively enrolled. The patients were divided into 2 groups based on aortic valve replacement (AVR) after enrollment: a non-AVR group (n=112), and an AVR group (n=118). The primary clinical endpoint was cardiovascular events, which were defined as cardiovascular death or hospitalization. Coronary artery disease [hazard ratio (HR): 3.62, 95% confidence interval (CI): 1.585–8.245, P

Original languageEnglish
Pages (from-to)519-525
Number of pages7
JournalCirculation Journal
Volume80
Issue number2
DOIs
Publication statusPublished - Jan 25 2016

    Fingerprint

Keywords

  • Aortic stenosis
  • Coronary artery disease
  • Echocardiography
  • Valve disease surgery
  • Valvular heart disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Shibayama, K., Daimon, M., Watanabe, H., Kawata, T., Miyazaki, S., Morimoto-Ichikawa, R., Maruyama, M., Chiang, S. J., Miyauchi, K., & Daida, H. (2016). Significance of coronary artery disease and left ventricular afterload in unoperated asymptomatic aortic stenosis. Circulation Journal, 80(2), 519-525. https://doi.org/10.1253/circj.CJ-15-0876