Serum uric acid, hyperuricemia and body mass index in children and adolescents with intellectual disabilities

Jin Ding Lin, Pei Ying Lin, Lan Ping Lin, Shang Wei Hsu, Chia Feng Yen, Wen Hui Fang, Sheng Ru Wu, Wu Chien Chien, Ching Hui Loh, Cordia M. Chu

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The aims of the preset study were to describe the profile of serum uric acid, the prevalence of hyperuricemia and its risk factors among children and adolescents with intellectual disabilities. We conducted a cross-sectional study of 941 children and adolescents with intellectual disabilities (aged 4-18 years) who participated in annual health examinations in three special schools in Taiwan. This study indicated 30.6% boys and 17.9% girls with intellectual disabilities were with hyperuricemia in Taiwan. The factors of gender, age and BMI were variables that can significantly predict the hyperuricemia occurrence in this vulnerable population. Those children and adolescents with intellectual disabilities were boys (OR = 2.93, 95% CI = 2.02-4.26) and older age (OR = 6.49, 95% CI = 2.19-19.21) were more likely to be hyperuricemia. With regard to BMI to hyperuricemia occurrence, those children and adolescents with intellectual disabilities were overweight (OR = 1.16-3.21, 95% CI = 1.16-3.21) and being obese (OR = 4.95-11.58, 95% CI = 4.95-11.58) was more likely to have a hyperuricemia than the normal weight group. This study provides the general profile of serum uric acid, hyperuricemia and its risk factors of children and adolescents with intellectual disabilities. Medical professionals should be highly alert to the possible consequences of hyperuricemia and provide useful information about the clinical manifestation of this condition for caregivers of children and adolescents with intellectual disabilities.

Original languageEnglish
Pages (from-to)1481-1489
Number of pages9
JournalResearch in Developmental Disabilities
Volume30
Issue number6
DOIs
Publication statusPublished - Nov 1 2009
Externally publishedYes

Fingerprint

Hyperuricemia
Uric Acid
Intellectual Disability
Body Mass Index
Serum
Taiwan
Age Factors
Vulnerable Populations
Caregivers
Cross-Sectional Studies
Weights and Measures
Health

Keywords

  • BMI
  • Gout
  • Hyperuricemia
  • Intellectual disabilities
  • Uric acid

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Clinical Psychology

Cite this

Serum uric acid, hyperuricemia and body mass index in children and adolescents with intellectual disabilities. / Lin, Jin Ding; Lin, Pei Ying; Lin, Lan Ping; Hsu, Shang Wei; Yen, Chia Feng; Fang, Wen Hui; Wu, Sheng Ru; Chien, Wu Chien; Loh, Ching Hui; Chu, Cordia M.

In: Research in Developmental Disabilities, Vol. 30, No. 6, 01.11.2009, p. 1481-1489.

Research output: Contribution to journalArticle

Lin, JD, Lin, PY, Lin, LP, Hsu, SW, Yen, CF, Fang, WH, Wu, SR, Chien, WC, Loh, CH & Chu, CM 2009, 'Serum uric acid, hyperuricemia and body mass index in children and adolescents with intellectual disabilities', Research in Developmental Disabilities, vol. 30, no. 6, pp. 1481-1489. https://doi.org/10.1016/j.ridd.2009.07.008
Lin, Jin Ding ; Lin, Pei Ying ; Lin, Lan Ping ; Hsu, Shang Wei ; Yen, Chia Feng ; Fang, Wen Hui ; Wu, Sheng Ru ; Chien, Wu Chien ; Loh, Ching Hui ; Chu, Cordia M. / Serum uric acid, hyperuricemia and body mass index in children and adolescents with intellectual disabilities. In: Research in Developmental Disabilities. 2009 ; Vol. 30, No. 6. pp. 1481-1489.
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