Serum lipid profiles are associated with semen quality

Chin Yu Liu, Yu Ching Chou, Shyh Hsiang Lin, Sheng Tang Wu, Tai Lung Cha, Hong I. Chen, Chih Wei Tsao

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We aimed to explore the associations between different lipid profiles and semen quality in a large-scale general male population. Sperm concentration, total sperm motility, progressive motility, and normal sperm morphology of total 7601 participants were recorded. The association of these semen parameters with the triglyceride, total cholesterol, high-density lipoprotein, low-density lipoprotein, and very low-density lipoprotein of serum lipid profiles was analyzed. Sperm concentration was statistically positively correlated with triglyceride and very low-density lipoprotein (adjusted P = 0.001 and P = 0.005, respectively). Total sperm motility and progressive motility were statistically increased with increasing low-density lipoprotein and cholesterol levels (both adjusted P = 0.008 and P < 0.001, respectively). The similar J-shaped associations (high-low-low-high) were noted between individual lipid profile and normal sperm morphology, especially low-density lipoprotein and cholesterol with statistical significance (adjusted P = 0.017 and P = 0.021, respectively). The prevalence of abnormal total sperm motility and progressive motility was decreased in participants with high levels of cholesterol (P = 0.008 and P = 0.019, respectively), and the reverse J-shaped associations (low-high-high-low) were noted between high-density lipoprotein, triglyceride, very low-density lipoprotein, and the prevalence of abnormal normal sperm morphology (P = 0.010, P = 0.037, and P = 0.025, respectively). A high cholesterol level was associated with better sperm motility. Similar J-shaped associations were noted between all lipid profiles and normal sperm morphology; meanwhile, the reverse J-shaped trends were identified between them and abnormal normal sperm morphology prevalence.

Original languageEnglish
Pages (from-to)633-638
Number of pages6
JournalAsian Journal of Andrology
Volume19
Issue number6
DOIs
Publication statusPublished - Nov 1 2017

Fingerprint

Semen Analysis
Sperm Motility
Spermatozoa
Lipids
Serum
VLDL Lipoproteins
Hypercholesterolemia
LDL Cholesterol
HDL Lipoproteins
Semen
LDL Lipoproteins
HDL Cholesterol
Triglycerides
Population

ASJC Scopus subject areas

  • Urology

Cite this

Liu, C. Y., Chou, Y. C., Lin, S. H., Wu, S. T., Cha, T. L., Chen, H. I., & Tsao, C. W. (2017). Serum lipid profiles are associated with semen quality. Asian Journal of Andrology, 19(6), 633-638. https://doi.org/10.4103/1008-682X.195240

Serum lipid profiles are associated with semen quality. / Liu, Chin Yu; Chou, Yu Ching; Lin, Shyh Hsiang; Wu, Sheng Tang; Cha, Tai Lung; Chen, Hong I.; Tsao, Chih Wei.

In: Asian Journal of Andrology, Vol. 19, No. 6, 01.11.2017, p. 633-638.

Research output: Contribution to journalArticle

Liu, CY, Chou, YC, Lin, SH, Wu, ST, Cha, TL, Chen, HI & Tsao, CW 2017, 'Serum lipid profiles are associated with semen quality', Asian Journal of Andrology, vol. 19, no. 6, pp. 633-638. https://doi.org/10.4103/1008-682X.195240
Liu, Chin Yu ; Chou, Yu Ching ; Lin, Shyh Hsiang ; Wu, Sheng Tang ; Cha, Tai Lung ; Chen, Hong I. ; Tsao, Chih Wei. / Serum lipid profiles are associated with semen quality. In: Asian Journal of Andrology. 2017 ; Vol. 19, No. 6. pp. 633-638.
@article{7981cb560cea4694b76306507fa4266e,
title = "Serum lipid profiles are associated with semen quality",
abstract = "We aimed to explore the associations between different lipid profiles and semen quality in a large-scale general male population. Sperm concentration, total sperm motility, progressive motility, and normal sperm morphology of total 7601 participants were recorded. The association of these semen parameters with the triglyceride, total cholesterol, high-density lipoprotein, low-density lipoprotein, and very low-density lipoprotein of serum lipid profiles was analyzed. Sperm concentration was statistically positively correlated with triglyceride and very low-density lipoprotein (adjusted P = 0.001 and P = 0.005, respectively). Total sperm motility and progressive motility were statistically increased with increasing low-density lipoprotein and cholesterol levels (both adjusted P = 0.008 and P < 0.001, respectively). The similar J-shaped associations (high-low-low-high) were noted between individual lipid profile and normal sperm morphology, especially low-density lipoprotein and cholesterol with statistical significance (adjusted P = 0.017 and P = 0.021, respectively). The prevalence of abnormal total sperm motility and progressive motility was decreased in participants with high levels of cholesterol (P = 0.008 and P = 0.019, respectively), and the reverse J-shaped associations (low-high-high-low) were noted between high-density lipoprotein, triglyceride, very low-density lipoprotein, and the prevalence of abnormal normal sperm morphology (P = 0.010, P = 0.037, and P = 0.025, respectively). A high cholesterol level was associated with better sperm motility. Similar J-shaped associations were noted between all lipid profiles and normal sperm morphology; meanwhile, the reverse J-shaped trends were identified between them and abnormal normal sperm morphology prevalence.",
author = "Liu, {Chin Yu} and Chou, {Yu Ching} and Lin, {Shyh Hsiang} and Wu, {Sheng Tang} and Cha, {Tai Lung} and Chen, {Hong I.} and Tsao, {Chih Wei}",
year = "2017",
month = "11",
day = "1",
doi = "10.4103/1008-682X.195240",
language = "English",
volume = "19",
pages = "633--638",
journal = "Asian Journal of Andrology",
issn = "1008-682X",
publisher = "Nature Publishing Group",
number = "6",

}

TY - JOUR

T1 - Serum lipid profiles are associated with semen quality

AU - Liu, Chin Yu

AU - Chou, Yu Ching

AU - Lin, Shyh Hsiang

AU - Wu, Sheng Tang

AU - Cha, Tai Lung

AU - Chen, Hong I.

AU - Tsao, Chih Wei

PY - 2017/11/1

Y1 - 2017/11/1

N2 - We aimed to explore the associations between different lipid profiles and semen quality in a large-scale general male population. Sperm concentration, total sperm motility, progressive motility, and normal sperm morphology of total 7601 participants were recorded. The association of these semen parameters with the triglyceride, total cholesterol, high-density lipoprotein, low-density lipoprotein, and very low-density lipoprotein of serum lipid profiles was analyzed. Sperm concentration was statistically positively correlated with triglyceride and very low-density lipoprotein (adjusted P = 0.001 and P = 0.005, respectively). Total sperm motility and progressive motility were statistically increased with increasing low-density lipoprotein and cholesterol levels (both adjusted P = 0.008 and P < 0.001, respectively). The similar J-shaped associations (high-low-low-high) were noted between individual lipid profile and normal sperm morphology, especially low-density lipoprotein and cholesterol with statistical significance (adjusted P = 0.017 and P = 0.021, respectively). The prevalence of abnormal total sperm motility and progressive motility was decreased in participants with high levels of cholesterol (P = 0.008 and P = 0.019, respectively), and the reverse J-shaped associations (low-high-high-low) were noted between high-density lipoprotein, triglyceride, very low-density lipoprotein, and the prevalence of abnormal normal sperm morphology (P = 0.010, P = 0.037, and P = 0.025, respectively). A high cholesterol level was associated with better sperm motility. Similar J-shaped associations were noted between all lipid profiles and normal sperm morphology; meanwhile, the reverse J-shaped trends were identified between them and abnormal normal sperm morphology prevalence.

AB - We aimed to explore the associations between different lipid profiles and semen quality in a large-scale general male population. Sperm concentration, total sperm motility, progressive motility, and normal sperm morphology of total 7601 participants were recorded. The association of these semen parameters with the triglyceride, total cholesterol, high-density lipoprotein, low-density lipoprotein, and very low-density lipoprotein of serum lipid profiles was analyzed. Sperm concentration was statistically positively correlated with triglyceride and very low-density lipoprotein (adjusted P = 0.001 and P = 0.005, respectively). Total sperm motility and progressive motility were statistically increased with increasing low-density lipoprotein and cholesterol levels (both adjusted P = 0.008 and P < 0.001, respectively). The similar J-shaped associations (high-low-low-high) were noted between individual lipid profile and normal sperm morphology, especially low-density lipoprotein and cholesterol with statistical significance (adjusted P = 0.017 and P = 0.021, respectively). The prevalence of abnormal total sperm motility and progressive motility was decreased in participants with high levels of cholesterol (P = 0.008 and P = 0.019, respectively), and the reverse J-shaped associations (low-high-high-low) were noted between high-density lipoprotein, triglyceride, very low-density lipoprotein, and the prevalence of abnormal normal sperm morphology (P = 0.010, P = 0.037, and P = 0.025, respectively). A high cholesterol level was associated with better sperm motility. Similar J-shaped associations were noted between all lipid profiles and normal sperm morphology; meanwhile, the reverse J-shaped trends were identified between them and abnormal normal sperm morphology prevalence.

UR - http://www.scopus.com/inward/record.url?scp=85032448393&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85032448393&partnerID=8YFLogxK

U2 - 10.4103/1008-682X.195240

DO - 10.4103/1008-682X.195240

M3 - Article

AN - SCOPUS:85032448393

VL - 19

SP - 633

EP - 638

JO - Asian Journal of Andrology

JF - Asian Journal of Andrology

SN - 1008-682X

IS - 6

ER -