Seroprevalence, seroconversion, and risk factors for toxoplasmosis among pregnant women in Taipei, Taiwan

Ching Sheng Hung, Hung Wen Su, Yu Luen Lee, Hui Wen Weng, Yin Chin Wang, Toshio Naito, Akiko Tsubouchi, Giueng Chueng Wang, Chia-Kwung Fan

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Herein, we determined the seroprevalence, seroconversion, and risk factors associated with Toxoplasma gondii (T. gondii) infection among pregnant women in Taipei, Taiwan. Pregnant women attending antenatal consultation in a Taipei medical center were invited, and 104 women completed a self-administered structured questionnaire. Venous blood samples were collected during the first and third trimester after consent was obtained. Serum IgG and IgM antibodies (Abs) as well as IgG avidity were analyzed using an enzyme-linked fluorescent assay. Of the samples collected in the first trimester, seven were seropositive for IgG Abs and one was seropositive for IgG + IgM Abs with a borderline avidity index, resulting in an overall seroprevalence of 7.7z. No statistically significant association was found between toxoplasmosis and age, pregnancy history, or any risk factors. Seroconversion was not detected from paired sera between the first and third trimesters. Pregnant women with senior high school education level or those who claimed to knowing Toxoplasma exhibited a significantly higher seroprevalence than those with bachelor degree (P = 0.05) or those who claimed not to have this knowledge (P = 0.05). Therefore, failure to understand the importance of T. gondii infection and the prevention measures resulted in the development of toxoplasmosis among these women.

Original languageEnglish
Pages (from-to)312-317
Number of pages6
JournalJapanese Journal of Infectious Diseases
Volume68
Issue number4
DOIs
Publication statusPublished - Jul 23 2015

Fingerprint

Toxoplasmosis
Seroepidemiologic Studies
Taiwan
Pregnant Women
First Pregnancy Trimester
Immunoglobulin G
Third Pregnancy Trimester
Immunoglobulin M
Antibodies
Reproductive History
Toxoplasma
Serum
Referral and Consultation
Education
Seroconversion
Enzymes

Keywords

  • Pregnant women
  • Risk factors
  • Seroprevalence
  • Taipei
  • Toxoplasma gondii

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Seroprevalence, seroconversion, and risk factors for toxoplasmosis among pregnant women in Taipei, Taiwan. / Hung, Ching Sheng; Su, Hung Wen; Lee, Yu Luen; Weng, Hui Wen; Wang, Yin Chin; Naito, Toshio; Tsubouchi, Akiko; Wang, Giueng Chueng; Fan, Chia-Kwung.

In: Japanese Journal of Infectious Diseases, Vol. 68, No. 4, 23.07.2015, p. 312-317.

Research output: Contribution to journalArticle

Hung, Ching Sheng ; Su, Hung Wen ; Lee, Yu Luen ; Weng, Hui Wen ; Wang, Yin Chin ; Naito, Toshio ; Tsubouchi, Akiko ; Wang, Giueng Chueng ; Fan, Chia-Kwung. / Seroprevalence, seroconversion, and risk factors for toxoplasmosis among pregnant women in Taipei, Taiwan. In: Japanese Journal of Infectious Diseases. 2015 ; Vol. 68, No. 4. pp. 312-317.
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