Seroprevalence of Toxoplasma gondii infection among pre-schoolchildren aged 1-5 years in the Democratic Republic of Sao Tome and Principe, Western Africa

Chia Kwung Fan, Chien Ching Hung, Kua Eyre Su, Fung Chang Sung, Hung Yi Chiou, Vilfrido Gil, Maria da Conceicao dos Reis Ferreira, Jose Manuel de Carvalho, Claudina Cruz, Yu Kuan Lin, Lian Fen Tseng, Ke Yun Sao, Wen Cheun Chang, Hung Shue Lan, Shing Hsien Chou

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The prevalence status of Toxoplasma gondii infection in children of the Democratic Republic of Sao Tome and Principe (DRSTP), Western Africa, is unknown to date. A serologic survey of T. gondii infection among pre-schoolchildren aged <5 years in the DRSTP was assessed by the latex agglutination (LA) test from November 2003 to March 2004. The overall seroprevalence of T. gondii infection was not low, reaching 21.49% (26/121). No significant gender difference in seroprevalence was found between boys (19.30%; 11/57) and girls (23.44%; 15/64) (X2=0.31, P = 0.58). The older age group of 4-5 years had significantly higher seroprevalence (36.67%; 11/30) than the younger age group of <2 years (10.34%; 3/29) (χ2 = 5.64, P = 0.02). It was noteworthy that the majority of seropositive boys (90.91%; 10/11) or older children aged ≥2 years (82.61%; 19/23) had high LA titres of ≥1:1024, indirectly indicating acute Toxoplasma infection. This study is the first report indicating that T. gondii infection is not low in pre-schoolchildren aged <5 years in the DRSTP. Whether the DRSTP pre-schoolchildren acquire T. gondii infection through constant exposure to the parasite from their daily activities owing to poor environmental hygiene should be further evaluated.

Original languageEnglish
Pages (from-to)446-449
Number of pages4
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume100
Issue number5
DOIs
Publication statusPublished - May 2006

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Atlantic Islands
Western Africa
Toxoplasmosis
Seroepidemiologic Studies
Toxoplasma
Age Groups
Latex Fixation Tests
Agglutination
Latex
Hygiene
Parasites
Infection

Keywords

  • Latex agglutination test
  • Pre-schoolchildren
  • Sao Tome and Principe
  • Seroprevalence
  • Toxoplasma gondii

ASJC Scopus subject areas

  • Parasitology
  • Medicine(all)

Cite this

Seroprevalence of Toxoplasma gondii infection among pre-schoolchildren aged 1-5 years in the Democratic Republic of Sao Tome and Principe, Western Africa. / Fan, Chia Kwung; Hung, Chien Ching; Su, Kua Eyre; Sung, Fung Chang; Chiou, Hung Yi; Gil, Vilfrido; dos Reis Ferreira, Maria da Conceicao; de Carvalho, Jose Manuel; Cruz, Claudina; Lin, Yu Kuan; Tseng, Lian Fen; Sao, Ke Yun; Chang, Wen Cheun; Lan, Hung Shue; Chou, Shing Hsien.

In: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 100, No. 5, 05.2006, p. 446-449.

Research output: Contribution to journalArticle

Fan, CK, Hung, CC, Su, KE, Sung, FC, Chiou, HY, Gil, V, dos Reis Ferreira, MDC, de Carvalho, JM, Cruz, C, Lin, YK, Tseng, LF, Sao, KY, Chang, WC, Lan, HS & Chou, SH 2006, 'Seroprevalence of Toxoplasma gondii infection among pre-schoolchildren aged 1-5 years in the Democratic Republic of Sao Tome and Principe, Western Africa', Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 100, no. 5, pp. 446-449. https://doi.org/10.1016/j.trstmh.2005.07.013
Fan, Chia Kwung ; Hung, Chien Ching ; Su, Kua Eyre ; Sung, Fung Chang ; Chiou, Hung Yi ; Gil, Vilfrido ; dos Reis Ferreira, Maria da Conceicao ; de Carvalho, Jose Manuel ; Cruz, Claudina ; Lin, Yu Kuan ; Tseng, Lian Fen ; Sao, Ke Yun ; Chang, Wen Cheun ; Lan, Hung Shue ; Chou, Shing Hsien. / Seroprevalence of Toxoplasma gondii infection among pre-schoolchildren aged 1-5 years in the Democratic Republic of Sao Tome and Principe, Western Africa. In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 2006 ; Vol. 100, No. 5. pp. 446-449.
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abstract = "The prevalence status of Toxoplasma gondii infection in children of the Democratic Republic of Sao Tome and Principe (DRSTP), Western Africa, is unknown to date. A serologic survey of T. gondii infection among pre-schoolchildren aged <5 years in the DRSTP was assessed by the latex agglutination (LA) test from November 2003 to March 2004. The overall seroprevalence of T. gondii infection was not low, reaching 21.49{\%} (26/121). No significant gender difference in seroprevalence was found between boys (19.30{\%}; 11/57) and girls (23.44{\%}; 15/64) (X2=0.31, P = 0.58). The older age group of 4-5 years had significantly higher seroprevalence (36.67{\%}; 11/30) than the younger age group of <2 years (10.34{\%}; 3/29) (χ2 = 5.64, P = 0.02). It was noteworthy that the majority of seropositive boys (90.91{\%}; 10/11) or older children aged ≥2 years (82.61{\%}; 19/23) had high LA titres of ≥1:1024, indirectly indicating acute Toxoplasma infection. This study is the first report indicating that T. gondii infection is not low in pre-schoolchildren aged <5 years in the DRSTP. Whether the DRSTP pre-schoolchildren acquire T. gondii infection through constant exposure to the parasite from their daily activities owing to poor environmental hygiene should be further evaluated.",
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AU - Su, Kua Eyre

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AU - Lin, Yu Kuan

AU - Tseng, Lian Fen

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