Seroprevalence of Toxocara spp. infection in Southeast Asia and Taiwan

Chia Mei Chou, Chia Kwung Fan

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Human toxocariasis is a worldwide neglected zoonotic parasitic disease and caused mainly by Toxocara canis, and to a lesser event, by T. cati. There are only 16 epidemiological studies and 5 clinical toxocariasis case reports in 11 Southeast Asia countries and Taiwan (SEAT) that were found by searching data from PubMed in the period from January 1992 to August 2019. The overall seroprevalence in SEAT varied from 3.9% to 84.6% chiefly detected by using T. canis larval excretory-secretory antigen (TcES)-based ELISA. Playing with dogs or contacting Toxocara eggs from the contaminated soil or vegetables or eating raw meats/viscera containing encapsulated larvae seem likely the major risk factors leading to human toxocariasis in SEAT. Nevertheless, undertaking comprehensive seroepidemiological studies to establish the baseline data and beware of clinical toxocariasis cases by physicians as well as establishing adequate serodiagnostic methods in detection of Toxocara infection, e.g., TcES-based immunoblotting method in helminth endemic SEA are strongly required.

Original languageEnglish
Title of host publicationAdvances in Parasitology
PublisherAcademic Press Inc.
DOIs
Publication statusAccepted/In press - Jan 1 2020

Publication series

NameAdvances in Parasitology
ISSN (Print)0065-308X

Keywords

  • Contact with dogs
  • Human toxocariasis
  • Seroprevalence
  • Soil contamination
  • Southeast Asia
  • Taiwan
  • Toxocara spp.

ASJC Scopus subject areas

  • Parasitology

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    Chou, C. M., & Fan, C. K. (Accepted/In press). Seroprevalence of Toxocara spp. infection in Southeast Asia and Taiwan. In Advances in Parasitology (Advances in Parasitology). Academic Press Inc.. https://doi.org/10.1016/bs.apar.2020.01.020