Seroprevalence of Toxocara canis infection among children in Swaziland, southern Africa

C. W. Liao, H. Sukati, P. D'lamini, C. M. Chou, Y. H. Liu, Y. C. Huang, M. H. Chung, J. S. Mtsetfwa, J. Jonato, W. T. Chiu, P. W S Chang, W. Y. Du, H. C. Chan, T. B. Chu, H. C. Cheng, W. W. Su, C. C. Tu, Cheng C.-Y. Cheng, C. K. Fan

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

As there appeared to be no data available on Toxocara canis infection in the children of Swaziland, a serological survey of T. canis infection was recently conducted among 92 children aged 3-12 years from rural slums in the lowand middle-veld. A child was considered seropositive if, in western blots based on the excretory-secretory antigens of larval T. canis, his or her serum gave a positive result when diluted 1 : 64. Forty-one (44.6%) of the children were found seropositive. There were no statistically significant differences in seroprevalence between the 49 boys and 43 girls investigated (46.9% v. 41.8%) or between the eight subjects aged 12 years and the 47 aged (5 years (62.5% v. 38.3%); the corresponding odds ratios were 0.81 (95% confidence interval50.36-1.86; P50.62) and 2.69 (95% confidence interval50.57-12.62; P50.20), respectively. The 66 subjects from the middleveld were, however, significantly more likely to be seropositive than the 26 subjects from the lowveld (54.5% v. 19.2%; odds ratio55.04, with a 95% confidence interval of 1.70-14.98; P,0.01). It seems likely that T. canis infection is common among the children who live in slums in Swaziland, particularly in the country's middleveld, probably as the result of poor hygiene and poor sanitation.

Original languageEnglish
Pages (from-to)73-80
Number of pages8
JournalAnnals of Tropical Medicine and Parasitology
Volume104
Issue number1
DOIs
Publication statusPublished - Jan 2010

Fingerprint

Swaziland
Toxocara canis
Southern Africa
Seroepidemiologic Studies
Poverty Areas
Infection
Sanitation
Hygiene
Western Blotting
Odds Ratio
Confidence Intervals
Antigens
Serum

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Seroprevalence of Toxocara canis infection among children in Swaziland, southern Africa. / Liao, C. W.; Sukati, H.; D'lamini, P.; Chou, C. M.; Liu, Y. H.; Huang, Y. C.; Chung, M. H.; Mtsetfwa, J. S.; Jonato, J.; Chiu, W. T.; Chang, P. W S; Du, W. Y.; Chan, H. C.; Chu, T. B.; Cheng, H. C.; Su, W. W.; Tu, C. C.; C.-Y. Cheng, Cheng; Fan, C. K.

In: Annals of Tropical Medicine and Parasitology, Vol. 104, No. 1, 01.2010, p. 73-80.

Research output: Contribution to journalArticle

Liao, CW, Sukati, H, D'lamini, P, Chou, CM, Liu, YH, Huang, YC, Chung, MH, Mtsetfwa, JS, Jonato, J, Chiu, WT, Chang, PWS, Du, WY, Chan, HC, Chu, TB, Cheng, HC, Su, WW, Tu, CC, C.-Y. Cheng, C & Fan, CK 2010, 'Seroprevalence of Toxocara canis infection among children in Swaziland, southern Africa', Annals of Tropical Medicine and Parasitology, vol. 104, no. 1, pp. 73-80. https://doi.org/10.1179/136485910X12607012373795
Liao, C. W. ; Sukati, H. ; D'lamini, P. ; Chou, C. M. ; Liu, Y. H. ; Huang, Y. C. ; Chung, M. H. ; Mtsetfwa, J. S. ; Jonato, J. ; Chiu, W. T. ; Chang, P. W S ; Du, W. Y. ; Chan, H. C. ; Chu, T. B. ; Cheng, H. C. ; Su, W. W. ; Tu, C. C. ; C.-Y. Cheng, Cheng ; Fan, C. K. / Seroprevalence of Toxocara canis infection among children in Swaziland, southern Africa. In: Annals of Tropical Medicine and Parasitology. 2010 ; Vol. 104, No. 1. pp. 73-80.
@article{f8bb60a4c4994d988e2e22f44cc69395,
title = "Seroprevalence of Toxocara canis infection among children in Swaziland, southern Africa",
abstract = "As there appeared to be no data available on Toxocara canis infection in the children of Swaziland, a serological survey of T. canis infection was recently conducted among 92 children aged 3-12 years from rural slums in the lowand middle-veld. A child was considered seropositive if, in western blots based on the excretory-secretory antigens of larval T. canis, his or her serum gave a positive result when diluted 1 : 64. Forty-one (44.6{\%}) of the children were found seropositive. There were no statistically significant differences in seroprevalence between the 49 boys and 43 girls investigated (46.9{\%} v. 41.8{\%}) or between the eight subjects aged 12 years and the 47 aged (5 years (62.5{\%} v. 38.3{\%}); the corresponding odds ratios were 0.81 (95{\%} confidence interval50.36-1.86; P50.62) and 2.69 (95{\%} confidence interval50.57-12.62; P50.20), respectively. The 66 subjects from the middleveld were, however, significantly more likely to be seropositive than the 26 subjects from the lowveld (54.5{\%} v. 19.2{\%}; odds ratio55.04, with a 95{\%} confidence interval of 1.70-14.98; P,0.01). It seems likely that T. canis infection is common among the children who live in slums in Swaziland, particularly in the country's middleveld, probably as the result of poor hygiene and poor sanitation.",
author = "Liao, {C. W.} and H. Sukati and P. D'lamini and Chou, {C. M.} and Liu, {Y. H.} and Huang, {Y. C.} and Chung, {M. H.} and Mtsetfwa, {J. S.} and J. Jonato and Chiu, {W. T.} and Chang, {P. W S} and Du, {W. Y.} and Chan, {H. C.} and Chu, {T. B.} and Cheng, {H. C.} and Su, {W. W.} and Tu, {C. C.} and {C.-Y. Cheng}, Cheng and Fan, {C. K.}",
year = "2010",
month = "1",
doi = "10.1179/136485910X12607012373795",
language = "English",
volume = "104",
pages = "73--80",
journal = "Pathogens and Global Health",
issn = "2047-7724",
publisher = "Maney Publishing",
number = "1",

}

TY - JOUR

T1 - Seroprevalence of Toxocara canis infection among children in Swaziland, southern Africa

AU - Liao, C. W.

AU - Sukati, H.

AU - D'lamini, P.

AU - Chou, C. M.

AU - Liu, Y. H.

AU - Huang, Y. C.

AU - Chung, M. H.

AU - Mtsetfwa, J. S.

AU - Jonato, J.

AU - Chiu, W. T.

AU - Chang, P. W S

AU - Du, W. Y.

AU - Chan, H. C.

AU - Chu, T. B.

AU - Cheng, H. C.

AU - Su, W. W.

AU - Tu, C. C.

AU - C.-Y. Cheng, Cheng

AU - Fan, C. K.

PY - 2010/1

Y1 - 2010/1

N2 - As there appeared to be no data available on Toxocara canis infection in the children of Swaziland, a serological survey of T. canis infection was recently conducted among 92 children aged 3-12 years from rural slums in the lowand middle-veld. A child was considered seropositive if, in western blots based on the excretory-secretory antigens of larval T. canis, his or her serum gave a positive result when diluted 1 : 64. Forty-one (44.6%) of the children were found seropositive. There were no statistically significant differences in seroprevalence between the 49 boys and 43 girls investigated (46.9% v. 41.8%) or between the eight subjects aged 12 years and the 47 aged (5 years (62.5% v. 38.3%); the corresponding odds ratios were 0.81 (95% confidence interval50.36-1.86; P50.62) and 2.69 (95% confidence interval50.57-12.62; P50.20), respectively. The 66 subjects from the middleveld were, however, significantly more likely to be seropositive than the 26 subjects from the lowveld (54.5% v. 19.2%; odds ratio55.04, with a 95% confidence interval of 1.70-14.98; P,0.01). It seems likely that T. canis infection is common among the children who live in slums in Swaziland, particularly in the country's middleveld, probably as the result of poor hygiene and poor sanitation.

AB - As there appeared to be no data available on Toxocara canis infection in the children of Swaziland, a serological survey of T. canis infection was recently conducted among 92 children aged 3-12 years from rural slums in the lowand middle-veld. A child was considered seropositive if, in western blots based on the excretory-secretory antigens of larval T. canis, his or her serum gave a positive result when diluted 1 : 64. Forty-one (44.6%) of the children were found seropositive. There were no statistically significant differences in seroprevalence between the 49 boys and 43 girls investigated (46.9% v. 41.8%) or between the eight subjects aged 12 years and the 47 aged (5 years (62.5% v. 38.3%); the corresponding odds ratios were 0.81 (95% confidence interval50.36-1.86; P50.62) and 2.69 (95% confidence interval50.57-12.62; P50.20), respectively. The 66 subjects from the middleveld were, however, significantly more likely to be seropositive than the 26 subjects from the lowveld (54.5% v. 19.2%; odds ratio55.04, with a 95% confidence interval of 1.70-14.98; P,0.01). It seems likely that T. canis infection is common among the children who live in slums in Swaziland, particularly in the country's middleveld, probably as the result of poor hygiene and poor sanitation.

UR - http://www.scopus.com/inward/record.url?scp=77949473240&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77949473240&partnerID=8YFLogxK

U2 - 10.1179/136485910X12607012373795

DO - 10.1179/136485910X12607012373795

M3 - Article

VL - 104

SP - 73

EP - 80

JO - Pathogens and Global Health

JF - Pathogens and Global Health

SN - 2047-7724

IS - 1

ER -