Seroprevalence of chlamydia pneumoniae in taiwan

Jen Hsien Wang, Yung Ching Liu, Deh Lin Cheng, Muh Yon Yeng, Yao Shen Chen, Bao Chen Chen

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Chlamydia pneumoniae (TWAR) is a relatively newly discovered respiratory tract pathogen which was first isolated in Taiwan. In order to describe the seroepidemiology of C. pneumoniae in Taiwan, we evaluated 1,085 stored serum samples: 904 from patients, 97 from umbilical cord blood samples, and 84 from medical personnel at the Veterans General Hospital-Kaohsiung, between January 1 and April 30, 1991. Antibodies were determined by the use of a microimmunofluorescence test using elementary bodies of C. pneumoniae AR-39 as antigen. Sera were tested with screening titres of 16 and 512 for immunoglobulin G antibody. The antibody prevalence was found to be 23.1% in young children (6 months to 10 years old), rising to 66.7% in teenagers, and to 96.2% in older age groups. These rates were higher than any reported earlier. The progressively increasing rates of seropositivity found in older individuals indicated a surge of reinfection in these age groups. Only 5 cases were found with micro-IF IgG titres equal to or greater than 512. All were asymptomatic according to the hospital records. In addition to a high prevalence rate in Taiwan, UK data also showed high infection rates in teenagers and elderly people.

Original languageEnglish
Pages (from-to)565-568
Number of pages4
JournalScandinavian Journal of Infectious Diseases
Volume25
Issue number5
DOIs
Publication statusPublished - 1993
Externally publishedYes

Fingerprint

Chlamydophila pneumoniae
Seroepidemiologic Studies
Taiwan
Antibodies
Age Groups
Immunoglobulin G
Veterans Hospitals
Hospital Records
Serum
Fetal Blood
General Hospitals
Respiratory System
Antigens
Infection

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology and Microbiology(all)
  • Infectious Diseases
  • Immunology

Cite this

Seroprevalence of chlamydia pneumoniae in taiwan. / Wang, Jen Hsien; Liu, Yung Ching; Cheng, Deh Lin; Yeng, Muh Yon; Chen, Yao Shen; Chen, Bao Chen.

In: Scandinavian Journal of Infectious Diseases, Vol. 25, No. 5, 1993, p. 565-568.

Research output: Contribution to journalArticle

Wang, Jen Hsien ; Liu, Yung Ching ; Cheng, Deh Lin ; Yeng, Muh Yon ; Chen, Yao Shen ; Chen, Bao Chen. / Seroprevalence of chlamydia pneumoniae in taiwan. In: Scandinavian Journal of Infectious Diseases. 1993 ; Vol. 25, No. 5. pp. 565-568.
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