Serial MRI studies in pathologically verified Balo's concentric sclerosis

Chi Jen Chen, Long Sun Ro, Chen Nen Chang, Yat Sen Ho, Chin Song Lu

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We report serial MRI studies in a patient with Balo's concentric sclerosis, who presented with a progressive weakness in the right limbs of 10 day duration. Serial MR images revealed several concentric lesions characterized by layer by layer of demyelinated and myelinated appearance and multiple plaques in the white matter. Pathological study of a biopsy of a concentric lesion (which was performed to rule out neoplasm) further confirmed this diagnosis. These MR findings resolved in correspondence with clinical improvement. The patient was almost completely normal 1 year later. In conclusion, in this case, we found that MRI could show the striking feature reminiscent of the histopathologic findings of Balo's concentric sclerosis and played an important role in antemortem diagnosis of this rare demyelinating disease.

Original languageEnglish
Pages (from-to)732-735
Number of pages4
JournalJournal of Computer Assisted Tomography
Volume20
Issue number5
DOIs
Publication statusPublished - Sep 1996
Externally publishedYes

Fingerprint

Diffuse Cerebral Sclerosis of Schilder
Demyelinating Diseases
Rare Diseases
Extremities
Biopsy
Neoplasms

Keywords

  • Brain, demyelination
  • Brain, diseases
  • Central nervous system, diseases
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Serial MRI studies in pathologically verified Balo's concentric sclerosis. / Chen, Chi Jen; Ro, Long Sun; Chang, Chen Nen; Ho, Yat Sen; Lu, Chin Song.

In: Journal of Computer Assisted Tomography, Vol. 20, No. 5, 09.1996, p. 732-735.

Research output: Contribution to journalArticle

Chen, Chi Jen ; Ro, Long Sun ; Chang, Chen Nen ; Ho, Yat Sen ; Lu, Chin Song. / Serial MRI studies in pathologically verified Balo's concentric sclerosis. In: Journal of Computer Assisted Tomography. 1996 ; Vol. 20, No. 5. pp. 732-735.
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