Serial cytogenetic studies of nonendemic Burkitt's lymphoma cell lines

E. C. Douglass, I. T. Magrath, E. C. Lee, J. Whang-Peng

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Cytogenetic study of nonendemic Burkitt's lymphoma (BL) cell lines showed a translocation of chromosomes #8 and #14, t(8;14), present in 16 of the 18 lines examined. Serial cytogenetic studies of nine of these lines showed that t(8;14) to be stable and present in all cells examined. Although many other chromosome aberrations were present, they did not demonstrate the stability or the pervasiveness of the t(8;14). The significance of these results and previously reported cytogenetic studies on the etiology of BL was discussed.

Original languageEnglish
Pages (from-to)891-895
Number of pages5
JournalJournal of the National Cancer Institute
Issue number5
Publication statusPublished - Dec 1 1980
Externally publishedYes


ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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