Serial cytogenetic studies of nonendemic Burkitt's lymphoma cell lines

E. C. Douglass, I. T. Magrath, E. C. Lee, J. Whang-Peng

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Cytogenetic study of nonendemic Burkitt's lymphoma (BL) cell lines showed a translocation of chromosomes #8 and #14, t(8;14), present in 16 of the 18 lines examined. Serial cytogenetic studies of nine of these lines showed that t(8;14) to be stable and present in all cells examined. Although many other chromosome aberrations were present, they did not demonstrate the stability or the pervasiveness of the t(8;14). The significance of these results and previously reported cytogenetic studies on the etiology of BL was discussed.

Original languageEnglish
Pages (from-to)891-895
Number of pages5
JournalJournal of the National Cancer Institute
Volume65
Issue number5
Publication statusPublished - Dec 1 1980
Externally publishedYes

Fingerprint

Burkitt Lymphoma
Cytogenetics
Cell Line
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 8
Chromosome Aberrations

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Serial cytogenetic studies of nonendemic Burkitt's lymphoma cell lines. / Douglass, E. C.; Magrath, I. T.; Lee, E. C.; Whang-Peng, J.

In: Journal of the National Cancer Institute, Vol. 65, No. 5, 01.12.1980, p. 891-895.

Research output: Contribution to journalArticle

Douglass, E. C. ; Magrath, I. T. ; Lee, E. C. ; Whang-Peng, J. / Serial cytogenetic studies of nonendemic Burkitt's lymphoma cell lines. In: Journal of the National Cancer Institute. 1980 ; Vol. 65, No. 5. pp. 891-895.
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