Sentinel node biopsy in early breast cancer in Taiwan

Jyh Cherng Yu, Giu Cheng Hsu, Yao Chi Liu, Lai Fa Sheu, Su Hui Li, Tsu Yi Chao

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The purpose of this study is to report the results of sentinel node (SN) biopsy for assessment of early breast cancer in Taiwan and to compare our results with those in other Asian countries and worldwide. We used methylene blue dye to identify SN in patients with clinically non-palpable breast mass and palpable breast mass smaller than 3 cm. We also explored the role of imprint cytology and immunochemical studies to identify metastatic cancer cells in the lymph nodes. A total of 221 procedures on 218 patients were performed by a single surgeon. The SN was identified in 85.5% of the cases. The overall accuracy of identifying tumors in SN was 97.4%, with a sensitivity of 90.9%, specificity of 100%, positive predictive value of 100%, and negative predictive value of 96.4%. The use of immunochemical techniques helped to identify micrometastasis in SN or non-SN. Our results on SN biopsy with the dye method were similar to those reported from Japan and elsewhere. We concluded that sentinel node biopsy, together with the use of immunochemical techniques to identify micrometastatic foci, has allowed surgeons to decide at the time of surgery whether to perform axillary node dissection.

Original languageEnglish
Pages (from-to)1365-1369
Number of pages5
JournalWorld Journal of Surgery
Volume26
Issue number11
DOIs
Publication statusPublished - Nov 2002
Externally publishedYes

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Taiwan
Breast Neoplasms
Biopsy
Breast
Coloring Agents
Neoplasm Micrometastasis
Methylene Blue
cyhalothrin
Cell Biology
Dissection
Neoplasms
Japan
Lymph Nodes
Sensitivity and Specificity

ASJC Scopus subject areas

  • Surgery

Cite this

Yu, J. C., Hsu, G. C., Liu, Y. C., Sheu, L. F., Li, S. H., & Chao, T. Y. (2002). Sentinel node biopsy in early breast cancer in Taiwan. World Journal of Surgery, 26(11), 1365-1369. https://doi.org/10.1007/s00268-002-6390-9

Sentinel node biopsy in early breast cancer in Taiwan. / Yu, Jyh Cherng; Hsu, Giu Cheng; Liu, Yao Chi; Sheu, Lai Fa; Li, Su Hui; Chao, Tsu Yi.

In: World Journal of Surgery, Vol. 26, No. 11, 11.2002, p. 1365-1369.

Research output: Contribution to journalArticle

Yu, JC, Hsu, GC, Liu, YC, Sheu, LF, Li, SH & Chao, TY 2002, 'Sentinel node biopsy in early breast cancer in Taiwan', World Journal of Surgery, vol. 26, no. 11, pp. 1365-1369. https://doi.org/10.1007/s00268-002-6390-9
Yu, Jyh Cherng ; Hsu, Giu Cheng ; Liu, Yao Chi ; Sheu, Lai Fa ; Li, Su Hui ; Chao, Tsu Yi. / Sentinel node biopsy in early breast cancer in Taiwan. In: World Journal of Surgery. 2002 ; Vol. 26, No. 11. pp. 1365-1369.
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