Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

An Ping Huo, Kang Cheng Su, Hsien Tzung Liao, Chung Tei Chou, Hsiao Ning Chang

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

Original languageEnglish
Pages (from-to)296-299
Number of pages4
JournalJournal of Microbiology, Immunology and Infection
Volume38
Issue number4
Publication statusPublished - Aug 2005
Externally publishedYes

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Keywords

  • Heart block
  • Ribonuclearprotein antigen
  • SS-A antibodies
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology and Allergy
  • Immunology and Microbiology(all)

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