Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

An Ping Huo, Kang Cheng Su, Hsien Tzung Liao, Chung Tei Chou, Hsiao Ning Chang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

Original languageEnglish
Pages (from-to)296-299
Number of pages4
JournalJournal of Microbiology, Immunology and Infection
Volume38
Issue number4
Publication statusPublished - Aug 2005
Externally publishedYes

Fingerprint

Atrioventricular Block
Systemic Lupus Erythematosus
Electrocardiography
Methylprednisolone
Serologic Tests
Intravenous Infusions
Anti-Idiotypic Antibodies
Steroids
SS-B antibodies
Therapeutics

Keywords

  • Heart block
  • Ribonuclearprotein antigen
  • SS-A antibodies
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology and Allergy
  • Immunology and Microbiology(all)

Cite this

Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus. / Huo, An Ping; Su, Kang Cheng; Liao, Hsien Tzung; Chou, Chung Tei; Chang, Hsiao Ning.

In: Journal of Microbiology, Immunology and Infection, Vol. 38, No. 4, 08.2005, p. 296-299.

Research output: Contribution to journalArticle

Huo, An Ping ; Su, Kang Cheng ; Liao, Hsien Tzung ; Chou, Chung Tei ; Chang, Hsiao Ning. / Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus. In: Journal of Microbiology, Immunology and Infection. 2005 ; Vol. 38, No. 4. pp. 296-299.
@article{f7c3ac956bf443388df8562133b9e088,
title = "Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus",
abstract = "Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sj{\"o}gren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.",
keywords = "Heart block, Ribonuclearprotein antigen, SS-A antibodies, Systemic lupus erythematosus",
author = "Huo, {An Ping} and Su, {Kang Cheng} and Liao, {Hsien Tzung} and Chou, {Chung Tei} and Chang, {Hsiao Ning}",
year = "2005",
month = "8",
language = "English",
volume = "38",
pages = "296--299",
journal = "Journal of Microbiology, Immunology and Infection",
issn = "0253-2662",
publisher = "Elsevier Taiwan LLC",
number = "4",

}

TY - JOUR

T1 - Second-degree atrioventricular block as an early manifestation of adult systemic lupus erythematosus

AU - Huo, An Ping

AU - Su, Kang Cheng

AU - Liao, Hsien Tzung

AU - Chou, Chung Tei

AU - Chang, Hsiao Ning

PY - 2005/8

Y1 - 2005/8

N2 - Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

AB - Second-degree atrioventricular (AV) block had not been reported as an early manifestation of adult systemic lupus erythematosus (SLE). An 18-year-old woman of SLE presented with asymptomatic second-degree AV block with 2:1 conduction block on electrocardiogram (ECG) during admission. Serologic tests were negative for anti-Sjögren's syndrome A (anti-SS-A/Ro) and anti-SS-B/La antibodies, but positive for anti-ribonuclearprotein antibodies. Her abnormal ECG completely resolved soon after high-dose intravenous methylprednisolone infusion, and she was maintained successfully with a low dose of oral steroid. The possible pathogenesis of this complication is discussed. Follow-up with periodical ECG is recommended for adult lupus patients to screen for possible conduction system involvement, and treatment should be started as soon as possible.

KW - Heart block

KW - Ribonuclearprotein antigen

KW - SS-A antibodies

KW - Systemic lupus erythematosus

UR - http://www.scopus.com/inward/record.url?scp=24744453330&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=24744453330&partnerID=8YFLogxK

M3 - Article

VL - 38

SP - 296

EP - 299

JO - Journal of Microbiology, Immunology and Infection

JF - Journal of Microbiology, Immunology and Infection

SN - 0253-2662

IS - 4

ER -