Sarcomatoid carcinoma of the parotid gland with apparent metastasis of epidermoid elements to cervical lymph nodes

Shiang Fu Huang, I. How Chen, Chun Ta Liao, Tsung-Ming Chen, Kam Fai Lee

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A case of sarcomatoid carcinoma of the parotid gland is described in a 47-year-old male. Despite radical surgery and postoperative chemoradiation therapy, a distant metastasis occurred 1 month after treatment. The primary site was composed of well-differentiated squamous cell carcinoma intermingled with spindle-shaped malignant mesenchymal cells. Immunohistochemical studies showed that keratin was present in both epithelial cells and spindle cells, whereas vimentin was present in spindle cells and absent in epithelial cells. Two lymph nodes were metastasized by the epidermoid component. The origin of the sarcomatoid component and the differential diagnosis from malignant mixed tumours are discussed.

Original languageEnglish
Pages (from-to)667-671
Number of pages5
JournalActa Oto-Laryngologica
Volume126
Issue number6
DOIs
Publication statusPublished - Jun 1 2006
Externally publishedYes

Keywords

  • Epithelial cells
  • Metastasis
  • Parotid gland
  • Sarcomatoid carcinoma
  • Spindle cells

ASJC Scopus subject areas

  • Otorhinolaryngology

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