Salivary glands

Echo-planar versus PROPELLER diffusion-weighted MR imaging for assessment of ADCs

Chun Jung Juan, Hing Chiu Chang, Chun Jen Hsueh, Hua Shan Liu, Yin Cheng Huang, Hsiao Wen Chung, Cheng Yu Chen, Hung Wen Kao, Guo Shu Huang

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Purpose: To compare the image distortion and the quantification variation in parotid gland apparent diffusion coefficients (ADCs) on periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) versus echoplanar diffusion-weighted (DW) magnetic resonance (MR) images and to investigate the relationship between parotid gland ADC and parotid gland fat content. Materials and Methods: This prospective study was approved by a local institutional review board. Written informed consent was obtained from all 33 enrolled healthy volunteers (15 men, 18 women; mean age, 36.4 years ± 11.8 [standard deviation]). All participants underwent 1.5-T non - fat-saturated and fat-saturated PROPELLER DW MR imaging as well as 1.5-T nonaccelerated and twofold-accelerated echo-planar DW MR imaging. Image distortion on the DW images was qualitatively scored, and parotid ADC was quantitatively analyzed. The correlation between parotid ADC and parotid fat content was evaluated by using linear regression analysis. Wilcoxon signed rank and t tests were used for statistical analysis, with Bonferroni correction applied for multiple comparisons. Results: Echo-planar DW images showed distortion, which was completely eliminated on the PROPELLER DW images. The mean parotid ADCs measured with non - fat-saturated PROPELLER (0.670 x 10-3 mm2/sec ± 0.149), nonaccelerated echo-planar (0.892 x 10-3 mm2/sec ± 0.128), twofold-accelerated echo-planar (1.088 x 10-3 mm2/sec x 0.124), and fat-saturated PROPELLER (1.307 x 10-3 mm2/sec ± 0.217) DW imaging differed significantly from one another (P <.001 for all comparisons). Parotid ADC had a significant negative correlation with parotid fat content (x) measured at non - fat-saturated PROPELLER DW imaging: ADC = -0.0087x + 1.1173 (r = 0.80, P <.001). Conclusion: PROPELLER DW imaging pulse sequences can yield distortion-free images for parotid ADC measurements and enable quantitative evaluation of the relationship between parotid ADC and parotid fat content.

Original languageEnglish
Pages (from-to)144-152
Number of pages9
JournalRadiology
Volume253
Issue number1
DOIs
Publication statusPublished - Oct 2009
Externally publishedYes

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Diffusion Magnetic Resonance Imaging
Salivary Glands
Fats
Parotid Gland
Echo-Planar Imaging
Research Ethics Committees
Informed Consent

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Juan, C. J., Chang, H. C., Hsueh, C. J., Liu, H. S., Huang, Y. C., Chung, H. W., ... Huang, G. S. (2009). Salivary glands: Echo-planar versus PROPELLER diffusion-weighted MR imaging for assessment of ADCs. Radiology, 253(1), 144-152. https://doi.org/10.1148/radiol.2531082228

Salivary glands : Echo-planar versus PROPELLER diffusion-weighted MR imaging for assessment of ADCs. / Juan, Chun Jung; Chang, Hing Chiu; Hsueh, Chun Jen; Liu, Hua Shan; Huang, Yin Cheng; Chung, Hsiao Wen; Chen, Cheng Yu; Kao, Hung Wen; Huang, Guo Shu.

In: Radiology, Vol. 253, No. 1, 10.2009, p. 144-152.

Research output: Contribution to journalArticle

Juan, CJ, Chang, HC, Hsueh, CJ, Liu, HS, Huang, YC, Chung, HW, Chen, CY, Kao, HW & Huang, GS 2009, 'Salivary glands: Echo-planar versus PROPELLER diffusion-weighted MR imaging for assessment of ADCs', Radiology, vol. 253, no. 1, pp. 144-152. https://doi.org/10.1148/radiol.2531082228
Juan, Chun Jung ; Chang, Hing Chiu ; Hsueh, Chun Jen ; Liu, Hua Shan ; Huang, Yin Cheng ; Chung, Hsiao Wen ; Chen, Cheng Yu ; Kao, Hung Wen ; Huang, Guo Shu. / Salivary glands : Echo-planar versus PROPELLER diffusion-weighted MR imaging for assessment of ADCs. In: Radiology. 2009 ; Vol. 253, No. 1. pp. 144-152.
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abstract = "Purpose: To compare the image distortion and the quantification variation in parotid gland apparent diffusion coefficients (ADCs) on periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) versus echoplanar diffusion-weighted (DW) magnetic resonance (MR) images and to investigate the relationship between parotid gland ADC and parotid gland fat content. Materials and Methods: This prospective study was approved by a local institutional review board. Written informed consent was obtained from all 33 enrolled healthy volunteers (15 men, 18 women; mean age, 36.4 years ± 11.8 [standard deviation]). All participants underwent 1.5-T non - fat-saturated and fat-saturated PROPELLER DW MR imaging as well as 1.5-T nonaccelerated and twofold-accelerated echo-planar DW MR imaging. Image distortion on the DW images was qualitatively scored, and parotid ADC was quantitatively analyzed. The correlation between parotid ADC and parotid fat content was evaluated by using linear regression analysis. Wilcoxon signed rank and t tests were used for statistical analysis, with Bonferroni correction applied for multiple comparisons. Results: Echo-planar DW images showed distortion, which was completely eliminated on the PROPELLER DW images. The mean parotid ADCs measured with non - fat-saturated PROPELLER (0.670 x 10-3 mm2/sec ± 0.149), nonaccelerated echo-planar (0.892 x 10-3 mm2/sec ± 0.128), twofold-accelerated echo-planar (1.088 x 10-3 mm2/sec x 0.124), and fat-saturated PROPELLER (1.307 x 10-3 mm2/sec ± 0.217) DW imaging differed significantly from one another (P <.001 for all comparisons). Parotid ADC had a significant negative correlation with parotid fat content (x) measured at non - fat-saturated PROPELLER DW imaging: ADC = -0.0087x + 1.1173 (r = 0.80, P <.001). Conclusion: PROPELLER DW imaging pulse sequences can yield distortion-free images for parotid ADC measurements and enable quantitative evaluation of the relationship between parotid ADC and parotid fat content.",
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AU - Hsueh, Chun Jen

AU - Liu, Hua Shan

AU - Huang, Yin Cheng

AU - Chung, Hsiao Wen

AU - Chen, Cheng Yu

AU - Kao, Hung Wen

AU - Huang, Guo Shu

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N2 - Purpose: To compare the image distortion and the quantification variation in parotid gland apparent diffusion coefficients (ADCs) on periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) versus echoplanar diffusion-weighted (DW) magnetic resonance (MR) images and to investigate the relationship between parotid gland ADC and parotid gland fat content. Materials and Methods: This prospective study was approved by a local institutional review board. Written informed consent was obtained from all 33 enrolled healthy volunteers (15 men, 18 women; mean age, 36.4 years ± 11.8 [standard deviation]). All participants underwent 1.5-T non - fat-saturated and fat-saturated PROPELLER DW MR imaging as well as 1.5-T nonaccelerated and twofold-accelerated echo-planar DW MR imaging. Image distortion on the DW images was qualitatively scored, and parotid ADC was quantitatively analyzed. The correlation between parotid ADC and parotid fat content was evaluated by using linear regression analysis. Wilcoxon signed rank and t tests were used for statistical analysis, with Bonferroni correction applied for multiple comparisons. Results: Echo-planar DW images showed distortion, which was completely eliminated on the PROPELLER DW images. The mean parotid ADCs measured with non - fat-saturated PROPELLER (0.670 x 10-3 mm2/sec ± 0.149), nonaccelerated echo-planar (0.892 x 10-3 mm2/sec ± 0.128), twofold-accelerated echo-planar (1.088 x 10-3 mm2/sec x 0.124), and fat-saturated PROPELLER (1.307 x 10-3 mm2/sec ± 0.217) DW imaging differed significantly from one another (P <.001 for all comparisons). Parotid ADC had a significant negative correlation with parotid fat content (x) measured at non - fat-saturated PROPELLER DW imaging: ADC = -0.0087x + 1.1173 (r = 0.80, P <.001). Conclusion: PROPELLER DW imaging pulse sequences can yield distortion-free images for parotid ADC measurements and enable quantitative evaluation of the relationship between parotid ADC and parotid fat content.

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