Salivary gland tumors: A 20-year review of clinical diagnostic accuracy at a single center

Wei Han Lee, Te Ming Tseng, Hsin Te Hsu, Fei Peng Lee, Shih Han Hung, Po Yueh Chen

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Obtaining reliable pre-operative diagnosis is crucial in planning treatment for patients with salivary gland tumors. The purpose of this study was to evaluate the accuracy of pre-operative clinical diagnosis of salivary gland tumors managed at a single tertiary university hospital over a period of 20 years. A retrospective analysis of the period between 1992 and 2011 was carried out to review the cases of patients with salivary gland tumors. A total of 101 patients were enrolled and general data were described. Clinical diagnosis was compared with the final pathological diagnosis to reveal the clinical diagnostic accuracy. Of the parotid and submandibular gland tumors, 86 and 67% were benign, respectively. The clinical diagnostic accuracies for diagnosis of parotid tumors as benign or malignant were 100 and 57%, respectively. The clinical diagnostic accuracies for diagnosis of submandibular tumors as benign or malignant were 67%. Therefore, the overall clinical judgment of benign and malignant tumors in the submandibular gland is unreliable. The accuracy for a parotid tumor to be clinically interpreted as benign was 100%. While it is difficult to draw any conclusion for non-parotid gland tumors, surgical intervention should be recommended in patients with parotid tumors clinically suspected to be malignant, and all submandibular, sublingual and minor salivary gland tumors.

Original languageEnglish
Pages (from-to)583-587
Number of pages5
JournalOncology Letters
Volume7
Issue number2
DOIs
Publication statusPublished - Feb 2014

Fingerprint

Glandular and Epithelial Neoplasms
Neoplasms
Submandibular Gland
Minor Salivary Glands
Parotid Gland
Tertiary Care Centers
Demography

Keywords

  • Diagnostic accuracy
  • Malignancy
  • Salivary gland neoplasm

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Salivary gland tumors : A 20-year review of clinical diagnostic accuracy at a single center. / Lee, Wei Han; Tseng, Te Ming; Hsu, Hsin Te; Lee, Fei Peng; Hung, Shih Han; Chen, Po Yueh.

In: Oncology Letters, Vol. 7, No. 2, 02.2014, p. 583-587.

Research output: Contribution to journalArticle

@article{318361aa87db477591be669b30e8eeb0,
title = "Salivary gland tumors: A 20-year review of clinical diagnostic accuracy at a single center",
abstract = "Obtaining reliable pre-operative diagnosis is crucial in planning treatment for patients with salivary gland tumors. The purpose of this study was to evaluate the accuracy of pre-operative clinical diagnosis of salivary gland tumors managed at a single tertiary university hospital over a period of 20 years. A retrospective analysis of the period between 1992 and 2011 was carried out to review the cases of patients with salivary gland tumors. A total of 101 patients were enrolled and general data were described. Clinical diagnosis was compared with the final pathological diagnosis to reveal the clinical diagnostic accuracy. Of the parotid and submandibular gland tumors, 86 and 67{\%} were benign, respectively. The clinical diagnostic accuracies for diagnosis of parotid tumors as benign or malignant were 100 and 57{\%}, respectively. The clinical diagnostic accuracies for diagnosis of submandibular tumors as benign or malignant were 67{\%}. Therefore, the overall clinical judgment of benign and malignant tumors in the submandibular gland is unreliable. The accuracy for a parotid tumor to be clinically interpreted as benign was 100{\%}. While it is difficult to draw any conclusion for non-parotid gland tumors, surgical intervention should be recommended in patients with parotid tumors clinically suspected to be malignant, and all submandibular, sublingual and minor salivary gland tumors.",
keywords = "Diagnostic accuracy, Malignancy, Salivary gland neoplasm",
author = "Lee, {Wei Han} and Tseng, {Te Ming} and Hsu, {Hsin Te} and Lee, {Fei Peng} and Hung, {Shih Han} and Chen, {Po Yueh}",
year = "2014",
month = "2",
doi = "10.3892/ol.2013.1750",
language = "English",
volume = "7",
pages = "583--587",
journal = "Oncology Letters",
issn = "1792-1074",
publisher = "Spandidos Publications",
number = "2",

}

TY - JOUR

T1 - Salivary gland tumors

T2 - A 20-year review of clinical diagnostic accuracy at a single center

AU - Lee, Wei Han

AU - Tseng, Te Ming

AU - Hsu, Hsin Te

AU - Lee, Fei Peng

AU - Hung, Shih Han

AU - Chen, Po Yueh

PY - 2014/2

Y1 - 2014/2

N2 - Obtaining reliable pre-operative diagnosis is crucial in planning treatment for patients with salivary gland tumors. The purpose of this study was to evaluate the accuracy of pre-operative clinical diagnosis of salivary gland tumors managed at a single tertiary university hospital over a period of 20 years. A retrospective analysis of the period between 1992 and 2011 was carried out to review the cases of patients with salivary gland tumors. A total of 101 patients were enrolled and general data were described. Clinical diagnosis was compared with the final pathological diagnosis to reveal the clinical diagnostic accuracy. Of the parotid and submandibular gland tumors, 86 and 67% were benign, respectively. The clinical diagnostic accuracies for diagnosis of parotid tumors as benign or malignant were 100 and 57%, respectively. The clinical diagnostic accuracies for diagnosis of submandibular tumors as benign or malignant were 67%. Therefore, the overall clinical judgment of benign and malignant tumors in the submandibular gland is unreliable. The accuracy for a parotid tumor to be clinically interpreted as benign was 100%. While it is difficult to draw any conclusion for non-parotid gland tumors, surgical intervention should be recommended in patients with parotid tumors clinically suspected to be malignant, and all submandibular, sublingual and minor salivary gland tumors.

AB - Obtaining reliable pre-operative diagnosis is crucial in planning treatment for patients with salivary gland tumors. The purpose of this study was to evaluate the accuracy of pre-operative clinical diagnosis of salivary gland tumors managed at a single tertiary university hospital over a period of 20 years. A retrospective analysis of the period between 1992 and 2011 was carried out to review the cases of patients with salivary gland tumors. A total of 101 patients were enrolled and general data were described. Clinical diagnosis was compared with the final pathological diagnosis to reveal the clinical diagnostic accuracy. Of the parotid and submandibular gland tumors, 86 and 67% were benign, respectively. The clinical diagnostic accuracies for diagnosis of parotid tumors as benign or malignant were 100 and 57%, respectively. The clinical diagnostic accuracies for diagnosis of submandibular tumors as benign or malignant were 67%. Therefore, the overall clinical judgment of benign and malignant tumors in the submandibular gland is unreliable. The accuracy for a parotid tumor to be clinically interpreted as benign was 100%. While it is difficult to draw any conclusion for non-parotid gland tumors, surgical intervention should be recommended in patients with parotid tumors clinically suspected to be malignant, and all submandibular, sublingual and minor salivary gland tumors.

KW - Diagnostic accuracy

KW - Malignancy

KW - Salivary gland neoplasm

UR - http://www.scopus.com/inward/record.url?scp=84890317852&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84890317852&partnerID=8YFLogxK

U2 - 10.3892/ol.2013.1750

DO - 10.3892/ol.2013.1750

M3 - Article

AN - SCOPUS:84890317852

VL - 7

SP - 583

EP - 587

JO - Oncology Letters

JF - Oncology Letters

SN - 1792-1074

IS - 2

ER -