Sad faces increase the heartbeat-associated interoceptive information flow within the salience network: a MEG study

Jaejoong Kim, Hyeong Dong Park, Ko Woon Kim, Dong Woo Shin, Sanghyun Lim, Hyukchan Kwon, Min Young Kim, Kiwoong Kim, Bumseok Jeong

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

The somatic marker hypothesis proposes that the cortical representation of visceral signals is a crucial component of emotional processing. No previous study has investigated the information flow among brain regions that process visceral information during emotional perception. In this magnetoencephalography study of 32 healthy subjects of either sex, heartbeat-evoked responses (HERs), which reflect the cortical processing of heartbeats, were modulated by the perception of a sad face. The modulation effect was localized to the prefrontal cortices, the globus pallidus, and an interoceptive network including the right anterior insula (RAI) and dorsal anterior cingulate cortex (RdACC). Importantly, our Granger causality analysis provides the first evidence for the increased flow of heartbeat information from the RAI to the RdACC during sad face perception. Moreover, using a surrogate R-peak analysis, we have shown that this HER modulation effect was time-locked to heartbeats. These findings advance the understanding of brain-body interactions during emotional processing.

Original languageEnglish
Article number430
JournalScientific Reports
Volume9
Issue number1
DOIs
Publication statusPublished - Dec 1 2019
Externally publishedYes

ASJC Scopus subject areas

  • General

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