Roughness-controlled self-assembly of nanorod-coverd mannitol/LB Agar microparticles by polymorphic transformation for pulmonary drug delivery

F. Zhang, N. Ngoc, B. H. Tay, R. Lau, Yu Hsuan Shao

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Novel roughness-controlled mannitol/LB Agar microcarriers with nanorod-covered surface were synthesized by polymorphic transformation and self-assembly method using hexane as the polymorphic transformation reagent and spray-dried mannitol/LB Agar microparticles as the starting material. With the size and amount of nanorods increasing, the surface roughness of the microparticles increase. An increase in the particle surface roughness can result in a better aerosolisation performance.

Original languageEnglish
Title of host publicationIEEE-NANO 2015 - 15th International Conference on Nanotechnology
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1505-1508
Number of pages4
ISBN (Print)9781467381550
DOIs
Publication statusPublished - 2015
Event15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015 - Rome, Italy
Duration: Jul 27 2015Jul 30 2015

Other

Other15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015
CountryItaly
CityRome
Period7/27/157/30/15

Keywords

  • image analysis
  • mannitol
  • nanorod-covered surface
  • polymorphic transformation
  • self-assembly

ASJC Scopus subject areas

  • Process Chemistry and Technology
  • Electrical and Electronic Engineering
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films

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  • Cite this

    Zhang, F., Ngoc, N., Tay, B. H., Lau, R., & Shao, Y. H. (2015). Roughness-controlled self-assembly of nanorod-coverd mannitol/LB Agar microparticles by polymorphic transformation for pulmonary drug delivery. In IEEE-NANO 2015 - 15th International Conference on Nanotechnology (pp. 1505-1508). [7388928] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NANO.2015.7388928