Rotavirus Gastroenteritis Associated with Afebrile Convulsion in Children: Clinical Analysis of 40 Cases

Jeng Juh Hung, Hsin Yi Wen, Meng Hsiu Yen, Hui Wen Chen, Dah Chin Yan, Kuang Lin Lin, Syh Jae Lin, Tzou Yien Lin, Chih Yi Hsu

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Background: The purpose of this study was to evaluate the clinical manifestations and outcomes of hospitalized children with afebrile seizures following rotavirus gastroenteritis. Methods: We conducted a retrospective study enrolling patients under 18 years old who were admitted to our hospital during a 10-year period with the diagnosis of rotavirus gastroenteritis. We identified and further analyzed patients who presented with afebrile seizures, without previous seizure disorders, electrolyte imbalances or hypoglycemia. The statistical methods used were the Chi-square test, the Kruskal-Wallis test and the Mann-Whitney test. Results: Of 1937 patients, 40 patients (24 female and 16 male patients) met the inclusion criteria. The incidence of afebrile seizures following rotavirus gastroenteritis was 2.06%. The age of the patients ranged from 6 months old to 6 years old (mean, 1.9 years). The highest incidence of afebrile seizures was 4.67% in children 1 to 2 years of age (p<0.001). Twenty-seven patients (67.5%) had two or more seizures, which usually were in clusters within a 24-hour period. No status epilepticus was observed. More than half of the patients (52.5%) suffered from seizures on the third day of diarrhea. Only five of 35 patients showed abnormal electroencephalogram (EEG) findings, which reverted to normal in four of the patients during the follow-up period. Most patients did not require long-term anticonvulsant treatment. During the follow-up period, all patients displayed normal psychomotor development without the recurrence of seizures, except in one patient who had a febrile convulsion. Conclusion: We found that the course of afebrile seizures following rotavirus gastroenteritis was benign with satisfactory outcomes.

Original languageEnglish
Pages (from-to)654-659
Number of pages6
JournalChang Gung Medical Journal
Volume26
Issue number9
Publication statusPublished - Sep 2003
Externally publishedYes

Fingerprint

Rotavirus
Gastroenteritis
Seizures
Febrile Seizures
Hospitalized Child
Status Epilepticus
Incidence
Chi-Square Distribution
Hypoglycemia
Anticonvulsants
Electrolytes
Electroencephalography
Diarrhea
Epilepsy
Retrospective Studies

Keywords

  • Afebrile seizure
  • Rotavirus gastroenteritis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hung, J. J., Wen, H. Y., Yen, M. H., Chen, H. W., Yan, D. C., Lin, K. L., ... Hsu, C. Y. (2003). Rotavirus Gastroenteritis Associated with Afebrile Convulsion in Children: Clinical Analysis of 40 Cases. Chang Gung Medical Journal, 26(9), 654-659.

Rotavirus Gastroenteritis Associated with Afebrile Convulsion in Children : Clinical Analysis of 40 Cases. / Hung, Jeng Juh; Wen, Hsin Yi; Yen, Meng Hsiu; Chen, Hui Wen; Yan, Dah Chin; Lin, Kuang Lin; Lin, Syh Jae; Lin, Tzou Yien; Hsu, Chih Yi.

In: Chang Gung Medical Journal, Vol. 26, No. 9, 09.2003, p. 654-659.

Research output: Contribution to journalArticle

Hung, JJ, Wen, HY, Yen, MH, Chen, HW, Yan, DC, Lin, KL, Lin, SJ, Lin, TY & Hsu, CY 2003, 'Rotavirus Gastroenteritis Associated with Afebrile Convulsion in Children: Clinical Analysis of 40 Cases', Chang Gung Medical Journal, vol. 26, no. 9, pp. 654-659.
Hung, Jeng Juh ; Wen, Hsin Yi ; Yen, Meng Hsiu ; Chen, Hui Wen ; Yan, Dah Chin ; Lin, Kuang Lin ; Lin, Syh Jae ; Lin, Tzou Yien ; Hsu, Chih Yi. / Rotavirus Gastroenteritis Associated with Afebrile Convulsion in Children : Clinical Analysis of 40 Cases. In: Chang Gung Medical Journal. 2003 ; Vol. 26, No. 9. pp. 654-659.
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AU - Chen, Hui Wen

AU - Yan, Dah Chin

AU - Lin, Kuang Lin

AU - Lin, Syh Jae

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N2 - Background: The purpose of this study was to evaluate the clinical manifestations and outcomes of hospitalized children with afebrile seizures following rotavirus gastroenteritis. Methods: We conducted a retrospective study enrolling patients under 18 years old who were admitted to our hospital during a 10-year period with the diagnosis of rotavirus gastroenteritis. We identified and further analyzed patients who presented with afebrile seizures, without previous seizure disorders, electrolyte imbalances or hypoglycemia. The statistical methods used were the Chi-square test, the Kruskal-Wallis test and the Mann-Whitney test. Results: Of 1937 patients, 40 patients (24 female and 16 male patients) met the inclusion criteria. The incidence of afebrile seizures following rotavirus gastroenteritis was 2.06%. The age of the patients ranged from 6 months old to 6 years old (mean, 1.9 years). The highest incidence of afebrile seizures was 4.67% in children 1 to 2 years of age (p<0.001). Twenty-seven patients (67.5%) had two or more seizures, which usually were in clusters within a 24-hour period. No status epilepticus was observed. More than half of the patients (52.5%) suffered from seizures on the third day of diarrhea. Only five of 35 patients showed abnormal electroencephalogram (EEG) findings, which reverted to normal in four of the patients during the follow-up period. Most patients did not require long-term anticonvulsant treatment. During the follow-up period, all patients displayed normal psychomotor development without the recurrence of seizures, except in one patient who had a febrile convulsion. Conclusion: We found that the course of afebrile seizures following rotavirus gastroenteritis was benign with satisfactory outcomes.

AB - Background: The purpose of this study was to evaluate the clinical manifestations and outcomes of hospitalized children with afebrile seizures following rotavirus gastroenteritis. Methods: We conducted a retrospective study enrolling patients under 18 years old who were admitted to our hospital during a 10-year period with the diagnosis of rotavirus gastroenteritis. We identified and further analyzed patients who presented with afebrile seizures, without previous seizure disorders, electrolyte imbalances or hypoglycemia. The statistical methods used were the Chi-square test, the Kruskal-Wallis test and the Mann-Whitney test. Results: Of 1937 patients, 40 patients (24 female and 16 male patients) met the inclusion criteria. The incidence of afebrile seizures following rotavirus gastroenteritis was 2.06%. The age of the patients ranged from 6 months old to 6 years old (mean, 1.9 years). The highest incidence of afebrile seizures was 4.67% in children 1 to 2 years of age (p<0.001). Twenty-seven patients (67.5%) had two or more seizures, which usually were in clusters within a 24-hour period. No status epilepticus was observed. More than half of the patients (52.5%) suffered from seizures on the third day of diarrhea. Only five of 35 patients showed abnormal electroencephalogram (EEG) findings, which reverted to normal in four of the patients during the follow-up period. Most patients did not require long-term anticonvulsant treatment. During the follow-up period, all patients displayed normal psychomotor development without the recurrence of seizures, except in one patient who had a febrile convulsion. Conclusion: We found that the course of afebrile seizures following rotavirus gastroenteritis was benign with satisfactory outcomes.

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