Roles of Resveratrol as Signaling Sensor and Gatekeeper

Ya-Jung Shih, Yi Ru Chen, Kuan Wang, Jacqueline Whang-Peng, Heng Yuan Tang, Hung-Yun Lin, Paul J. Davis

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Abstract

Resveratrol (trans-3,4′,5-trihydroxystilbene) is a natural phytoalexin that has pharmacological effects on several human diseases: cancer, coronary artery disease and neurodegenerative diseases. Many studies have reported the application of resveratrol as a preventive drug for these important conditions. In addition, recent reports indicate that resveratrol may also increase the lifespan of yeast and fruit flies. The positive effects of resveratrol have largely been demonstrated in vitro or in animal studies, with only limited and inconsistent effects reported in clinical studies. In addition, roles of resveratrol as signaling sensor and gatekeeper are still not clear. In this chapter, we will summarize a group of potentially important roles for resveratrol in diverse biological systems, particularly in metabolism and in cancer.
Original languageEnglish
Title of host publicationResveratrol: State-of-the-Art Science and Health Applications
PublisherWorld Scientific Publishing Co.
Pages115-144
Publication statusPublished - 2018

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Diptera
Neurodegenerative Diseases
resveratrol
Coronary Artery Disease
Fruit
Neoplasms
Yeasts
Pharmacology
Pharmaceutical Preparations
In Vitro Techniques
Clinical Studies
phytoalexins

Cite this

Shih, Y-J., Chen, Y. R., Wang, K., Whang-Peng, J., Tang, H. Y., Lin, H-Y., & Davis, P. J. (2018). Roles of Resveratrol as Signaling Sensor and Gatekeeper. In Resveratrol: State-of-the-Art Science and Health Applications (pp. 115-144). World Scientific Publishing Co..

Roles of Resveratrol as Signaling Sensor and Gatekeeper. / Shih, Ya-Jung; Chen, Yi Ru; Wang, Kuan; Whang-Peng, Jacqueline; Tang, Heng Yuan; Lin, Hung-Yun; Davis, Paul J.

Resveratrol: State-of-the-Art Science and Health Applications. World Scientific Publishing Co., 2018. p. 115-144.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Shih, Y-J, Chen, YR, Wang, K, Whang-Peng, J, Tang, HY, Lin, H-Y & Davis, PJ 2018, Roles of Resveratrol as Signaling Sensor and Gatekeeper. in Resveratrol: State-of-the-Art Science and Health Applications. World Scientific Publishing Co., pp. 115-144.
Shih Y-J, Chen YR, Wang K, Whang-Peng J, Tang HY, Lin H-Y et al. Roles of Resveratrol as Signaling Sensor and Gatekeeper. In Resveratrol: State-of-the-Art Science and Health Applications. World Scientific Publishing Co. 2018. p. 115-144
Shih, Ya-Jung ; Chen, Yi Ru ; Wang, Kuan ; Whang-Peng, Jacqueline ; Tang, Heng Yuan ; Lin, Hung-Yun ; Davis, Paul J. / Roles of Resveratrol as Signaling Sensor and Gatekeeper. Resveratrol: State-of-the-Art Science and Health Applications. World Scientific Publishing Co., 2018. pp. 115-144
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AU - Shih, Ya-Jung

AU - Chen, Yi Ru

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AU - Whang-Peng, Jacqueline

AU - Tang, Heng Yuan

AU - Lin, Hung-Yun

AU - Davis, Paul J.

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BT - Resveratrol: State-of-the-Art Science and Health Applications

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