Role of the blood vessel and arachnoid as conflicting structures during microvascular decompression for treating typical trigeminal neuralgia

Hsien Ta Hsu, Chun Jen Huang, Kuo Feng Huang, Ming Hsueh Lee, Hsing Hong Chen

Research output: Contribution to journalArticle

Abstract

Background/introduction The predominant cause of typical trigeminal neuralgia (TN) is the compression of the trigeminal nerve by an artery at the root entry zone. Arachnoid adhesion or venous contact with the trigeminal nerve has been infrequently identified during microvascular decompression (MVD). Purpose/aim This study aimed to elucidate the role of different types of vascular compression and arachnoid thickening in MVD for treating typical TN. Methods Patients with typical TN refractory to treatment with medications and scheduled for MVD were enrolled. Arterial compression of the trigeminal nerve was relieved using Teflon, whereas adhesiolysis was performed for arachnoid thickening. For a conflicting vein, a nearby artery was searched instead of coagulation and division of the vein. The postoperative outcomes were rated as excellent (complete resolution of pain), good (> 75% reduction in pain), poor (25–75% reduction in pain), and failure (< 25% reduction in pain). Results Between June 2000 and April 2015, a total of 27 patients undergoing MVD were enrolled in this study; one patient was lost to follow-up. The mean age of the remaining 26 patients was 57.4 ± 11.4 years (38–79 years), whereas the average duration of postoperative symptoms was 5.9 years (0.5–30 years). Significant differences in postoperative outcomes were noted for the arachnoid and artery compared with those for the vein as the conflicting structure, as evidenced by excellent and good outcomes (p = 0.005). Two operative complications were observed: cerebrospinal fluid rhinorrhea and deep wound infection. No mortality or cerebellar hemorrhage was observed during the follow-up period. Conclusion The tightness of the junction between the offending artery and the trigeminal nerve may represent a major factor affecting different postoperative outcomes following MVD. An offending artery may be attached to the arachnoid thickening, resulting in a neurovascular compressive effect, whereas the role of venous contact as a cause of TN remains debatable.

Original languageEnglish
Pages (from-to)142-148
Number of pages7
JournalFormosan Journal of Surgery
Volume49
Issue number4
DOIs
Publication statusPublished - Aug 1 2016
Externally publishedYes

Fingerprint

Microvascular Decompression Surgery
Arachnoid
Trigeminal Neuralgia
Trigeminal Nerve
Blood Vessels
Arteries
Pain
Veins
Cerebrospinal Fluid Rhinorrhea
Lost to Follow-Up
Polytetrafluoroethylene
Wound Infection
Hemorrhage
Mortality

Keywords

  • arachnoid thickening
  • microvascular decompression
  • offending artery
  • typical trigeminal neuralgia
  • vein

ASJC Scopus subject areas

  • Surgery

Cite this

Role of the blood vessel and arachnoid as conflicting structures during microvascular decompression for treating typical trigeminal neuralgia. / Hsu, Hsien Ta; Huang, Chun Jen; Huang, Kuo Feng; Lee, Ming Hsueh; Chen, Hsing Hong.

In: Formosan Journal of Surgery, Vol. 49, No. 4, 01.08.2016, p. 142-148.

Research output: Contribution to journalArticle

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abstract = "Background/introduction The predominant cause of typical trigeminal neuralgia (TN) is the compression of the trigeminal nerve by an artery at the root entry zone. Arachnoid adhesion or venous contact with the trigeminal nerve has been infrequently identified during microvascular decompression (MVD). Purpose/aim This study aimed to elucidate the role of different types of vascular compression and arachnoid thickening in MVD for treating typical TN. Methods Patients with typical TN refractory to treatment with medications and scheduled for MVD were enrolled. Arterial compression of the trigeminal nerve was relieved using Teflon, whereas adhesiolysis was performed for arachnoid thickening. For a conflicting vein, a nearby artery was searched instead of coagulation and division of the vein. The postoperative outcomes were rated as excellent (complete resolution of pain), good (> 75{\%} reduction in pain), poor (25–75{\%} reduction in pain), and failure (< 25{\%} reduction in pain). Results Between June 2000 and April 2015, a total of 27 patients undergoing MVD were enrolled in this study; one patient was lost to follow-up. The mean age of the remaining 26 patients was 57.4 ± 11.4 years (38–79 years), whereas the average duration of postoperative symptoms was 5.9 years (0.5–30 years). Significant differences in postoperative outcomes were noted for the arachnoid and artery compared with those for the vein as the conflicting structure, as evidenced by excellent and good outcomes (p = 0.005). Two operative complications were observed: cerebrospinal fluid rhinorrhea and deep wound infection. No mortality or cerebellar hemorrhage was observed during the follow-up period. Conclusion The tightness of the junction between the offending artery and the trigeminal nerve may represent a major factor affecting different postoperative outcomes following MVD. An offending artery may be attached to the arachnoid thickening, resulting in a neurovascular compressive effect, whereas the role of venous contact as a cause of TN remains debatable.",
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AU - Chen, Hsing Hong

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