Role of left main coronary artery stenosis on intraoperative conversion and mortality in off-pump coronary artery bypass

Jeng Wei Chen, Cheng Hsin Lin, Ron Bin Hsu

Research output: Contribution to journalArticle

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Abstract

Background: Intraoperative conversion is a major threat in off-pump coronary artery bypass (OPCAB). The conversion rate depends on patient selection and surgeon experience. Previous studies have demonstrated the feasibility of OPCAB for patients with left main coronary artery stenosis (LMCAS)≥50%. However, no studies have focused on the role of LMCAS≥90%.We sought to assess the impact of LMCAS≥90% on the conversion rate and mortality in OPCAB. Methods: We conducted a retrospective review of 1055 consecutive unselected patients undergoing OPCAB between 2000 and 2012. The patients in our study were divided into 3 groups by the severity of LMCAS. Results: LMCAS was <50% in 704, 50-90% in 266, and≥90% in 85 patients. LMCAS was not associated with major postoperative complications and hospitalmortality, although preoperative cardiogenic shock was present in 6.3%. Overall, the conversion rate was 10.1%:11.4% in LMCAS <50%, 5.6% in LMCAS 50-90%, and 14.1% in LMCAS≥90%. Operation status, cardiogenic shock, left ventricular ejection fraction <30% and operation before 2007were noted as independent predictors of conversion. The overall hospitalmortality rate was 5.1%: 4.8% in LMCAS <50%, 4.5% in LMCAS 50-90%, and 9.4% in LMCAS≥90%. Operation status, cardiogenic shock, left ventricular ejection fraction <30% and intraoperative conversion were observed to be independent predictors of mortality. However, LMCAS did not predict either conversion or hospital mortality. Conclusions: LMCAS≥90% was not an independent predictor of intraoperative conversion or hospital mortality in OPCAB.

Original languageEnglish
Pages (from-to)522-528
Number of pages7
JournalActa Cardiologica Sinica
Volume30
Issue number6
DOIs
Publication statusPublished - Nov 9 2014
Externally publishedYes

Fingerprint

Off-Pump Coronary Artery Bypass
Coronary Stenosis
Mortality
Cardiogenic Shock
Hospital Mortality
Stroke Volume
Patient Selection

Keywords

  • Conversion
  • Left main coronary artery stenosis
  • Off-pump coronary artery bypass

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Role of left main coronary artery stenosis on intraoperative conversion and mortality in off-pump coronary artery bypass. / Chen, Jeng Wei; Lin, Cheng Hsin; Hsu, Ron Bin.

In: Acta Cardiologica Sinica, Vol. 30, No. 6, 09.11.2014, p. 522-528.

Research output: Contribution to journalArticle

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abstract = "Background: Intraoperative conversion is a major threat in off-pump coronary artery bypass (OPCAB). The conversion rate depends on patient selection and surgeon experience. Previous studies have demonstrated the feasibility of OPCAB for patients with left main coronary artery stenosis (LMCAS)≥50{\%}. However, no studies have focused on the role of LMCAS≥90{\%}.We sought to assess the impact of LMCAS≥90{\%} on the conversion rate and mortality in OPCAB. Methods: We conducted a retrospective review of 1055 consecutive unselected patients undergoing OPCAB between 2000 and 2012. The patients in our study were divided into 3 groups by the severity of LMCAS. Results: LMCAS was <50{\%} in 704, 50-90{\%} in 266, and≥90{\%} in 85 patients. LMCAS was not associated with major postoperative complications and hospitalmortality, although preoperative cardiogenic shock was present in 6.3{\%}. Overall, the conversion rate was 10.1{\%}:11.4{\%} in LMCAS <50{\%}, 5.6{\%} in LMCAS 50-90{\%}, and 14.1{\%} in LMCAS≥90{\%}. Operation status, cardiogenic shock, left ventricular ejection fraction <30{\%} and operation before 2007were noted as independent predictors of conversion. The overall hospitalmortality rate was 5.1{\%}: 4.8{\%} in LMCAS <50{\%}, 4.5{\%} in LMCAS 50-90{\%}, and 9.4{\%} in LMCAS≥90{\%}. Operation status, cardiogenic shock, left ventricular ejection fraction <30{\%} and intraoperative conversion were observed to be independent predictors of mortality. However, LMCAS did not predict either conversion or hospital mortality. Conclusions: LMCAS≥90{\%} was not an independent predictor of intraoperative conversion or hospital mortality in OPCAB.",
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